| NMR in drug discovery M Pellecchia, DS Sem, K Wüthrich Nature Reviews Drug Discovery 1 (3), 211-219, 2002 | 610 | 2002 |
| Fluorescence-based detection of thiols in vitro and in vivo using dithiol probes PK Pullela, T Chiku, MJ Carvan III, DS Sem Analytical biochemistry 352 (2), 265-273, 2006 | 186 | 2006 |
| NMR-based structural characterization of large protein-ligand interactions M Pellecchia, D Meininger, Q Dong, E Chang, R Jack, DS Sem Journal of biomolecular NMR 22, 165-173, 2002 | 151 | 2002 |
| Inhibition of ribonucleotide reductase by gallium in murine leukemic L1210 cells CR Chitambar, J Narasimhan, J Guy, DS Sem, WJ O'Brien Cancer research 51 (22), 6199-6201, 1991 | 135 | 1991 |
| An in vitro spectroscopic analysis to determine whether para-chloroaniline is produced from mixing sodium hypochlorite and chlorhexidine JE Thomas, DS Sem Journal of endodontics 36 (2), 315-317, 2010 | 123 | 2010 |
| An in vitro spectroscopic analysis to determine the chemical composition of the precipitate formed by mixing sodium hypochlorite and chlorhexidine JB Nowicki, DS Sem Journal of endodontics 37 (7), 983-988, 2011 | 112 | 2011 |
| Intracellular DNA strand scission and growth inhibition of Ehrlich ascites tumor cells by bleomycins RW Byrnes, J Templin, D Sem, S Lyman, DH Petering Cancer Research 50 (17), 5275-5286, 1990 | 92 | 1990 |
| High-resolution solution structure of the retinoid X receptor DNA-binding domain SMA Holmbeck, MP Foster, DR Casimiro, DS Sem, HJ Dyson, PE Wright Journal of molecular biology 281 (2), 271-284, 1998 | 82 | 1998 |
| Mechanistic studies on the reductive half-reaction of NADPH-cytochrome P450 oxidoreductase AL Shen, DS Sem, CB Kasper Journal of Biological Chemistry 274 (9), 5391-5398, 1999 | 80 | 1999 |
| Interaction with arginine 597 of NADPH-cytochrome P-450 oxidoreductase is a primary source of the uniform binding energy used to discriminate between NADPH and NADH DS Sem, CB Kasper Biochemistry 32 (43), 11548-11558, 1993 | 65 | 1993 |
| Systems-based design of bi-ligand inhibitors of oxidoreductases: Filling the chemical proteomic toolbox DS Sem, B Bertolaet, B Baker, E Chang, AD Costache, S Coutts, Q Dong, ... Chemistry & biology 11 (2), 185-194, 2004 | 63 | 2004 |
| SEA-TROSY (solvent exposed amides with TROSY): a method to resolve the problem of spectral overlap in very large proteins M Pellecchia, D Meininger, AL Shen, R Jack, CB Kasper, DS Sem Journal of the American Chemical Society 123 (19), 4633-4634, 2001 | 63 | 2001 |
| Chemical proteomics-based analysis of off-target binding profiles for rosiglitazone and pioglitazone: clues for assessing potential for cardiotoxicity BR Hoffmann, MF El-Mansy, DS Sem, AS Greene Journal of medicinal chemistry 55 (19), 8260-8271, 2012 | 49 | 2012 |
| Sterol carrier protein-2: binding protein for endocannabinoids ES Liedhegner, CD Vogt, DS Sem, CW Cunningham, CJ Hillard Molecular neurobiology 50, 149-158, 2014 | 47 | 2014 |
| Synergistic use of compound properties and docking scores in neural network modeling of CYP2D6 binding: predicting affinity and conformational sampling PS Bazeley, S Prithivi, CA Struble, RJ Povinelli, DS Sem Journal of chemical information and modeling 46 (6), 2698-2708, 2006 | 46 | 2006 |
| Chemical proteomics-based drug design: target and antitarget fishing with a catechol− rhodanine privileged scaffold for NAD (P)(H) binding proteins X Ge, B Wakim, DS Sem Journal of medicinal chemistry 51 (15), 4571-4580, 2008 | 45 | 2008 |
| Effect of ionic strength on the kinetic mechanism and relative rate limitation of steps in the model NADPH-cytochrome P450 oxidoreductase reaction with cytochrome c DS Sem, CB Kasper Biochemistry 34 (39), 12768-12774, 1995 | 44 | 1995 |
| Structural evidence for a functionally relevant second camphor binding site in P450cam: Model for substrate entry into a P450 active site H Yao, CR McCullough, AD Costache, PK Pullela, DS Sem Proteins: Structure, Function, and Bioinformatics 69 (1), 125-138, 2007 | 43 | 2007 |
| Geometric relationship between the nicotinamide and isoalloxazine rings in NADPH-cytochrome P-450 oxidoreductase: implications for the classification of evolutionarily and … DS Sem, CB Kasper Biochemistry 31 (13), 3391-3398, 1992 | 43 | 1992 |
| Conserved amino acids in each subunit of the heteroligomeric tRNA m 1 A58 Mtase from Saccharomyces cerevisiae contribute to tRNA … SG Ozanick, JM Bujnicki, DS Sem, JT Anderson Nucleic acids research 35 (20), 6808-6819, 2007 | 42 | 2007 |
Maurizio PellecchiaUniversity of California RiversideZweryfikowany adres z ucr.edu