| Somatic mutations and cell identity linked by Genotyping of Transcriptomes AS Nam, KT Kim, R Chaligne, F Izzo, C Ang, J Taylor, RM Myers, ... Nature 571 (7765), 355-360, 2019 | 289 | 2019 |
| DNA methylation disruption reshapes the hematopoietic differentiation landscape F Izzo, SC Lee, A Poran, R Chaligne, F Gaiti, B Gross, RR Murali, ... Nature genetics 52 (4), 378-387, 2020 | 231 | 2020 |
| Epigenetic encoding, heritability and plasticity of glioma transcriptional cell states R Chaligne, F Gaiti, D Silverbush, JS Schiffman, HR Weisman, L Kluegel, ... Nature genetics 53 (10), 1469-1479, 2021 | 177 | 2021 |
| m6A RNA methylation maintains hematopoietic stem cell identity and symmetric commitment Y Cheng, H Luo, F Izzo, BF Pickering, D Nguyen, R Myers, A Schurer, ... Cell reports 28 (7), 1703-1716. e6, 2019 | 159 | 2019 |
| Inhibition of EZH2 catalytic activity selectively targets a metastatic subpopulation in triple-negative breast cancer S Yomtoubian, SB Lee, A Verma, F Izzo, G Markowitz, H Choi, L Cerchietti, ... Cell reports 30 (3), 755-770. e6, 2020 | 93 | 2020 |
| MiR-16 mediates trastuzumab and lapatinib response in ErbB-2-positive breast and gastric cancer via its novel targets CCNJ and FUBP1 L Venturutti, RI Cordo Russo, MA Rivas, MF Mercogliano, F Izzo, ... Oncogene 35 (48), 6189-6202, 2016 | 92 | 2016 |
| Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation AS Nam, N Dusaj, F Izzo, R Murali, RM Myers, TH Mouhieddine, J Sotelo, ... Nature genetics 54 (10), 1514-1526, 2022 | 91 | 2022 |
| Stat3 regulates ErbB-2 expression and co-opts ErbB-2 nuclear function to induce miR-21 expression, PDCD4 downregulation and breast cancer metastasis L Venturutti, LV Romero, AJ Urtreger, MF Chervo, RI Cordo Russo, ... Oncogene 35 (17), 2208-2222, 2016 | 78 | 2016 |
| Specification of fetal liver endothelial progenitors to functional zonated adult sinusoids requires c-Maf induction JM Gómez-Salinero, F Izzo, Y Lin, S Houghton, T Itkin, F Geng, Y Bram, ... Cell Stem Cell 29 (4), 593-609. e7, 2022 | 52 | 2022 |
| Acute myeloid leukemia iPSCs reveal a role for RUNX1 in the maintenance of human leukemia stem cells J Wesely, AG Kotini, F Izzo, H Luo, H Yuan, J Sun, M Georgomanoli, ... Cell reports 31 (9), 2020 | 45 | 2020 |
| Progesterone receptor activation downregulates GATA3 by transcriptional repression and increased protein turnover promoting breast tumor growth F Izzo, F Mercogliano, L Venturutti, M Tkach, G Inurrigarro, R Schillaci, ... Breast Cancer Research 16, 1-17, 2014 | 44 | 2014 |
| EpiMethylTag: simultaneous detection of ATAC-seq or ChIP-seq signals with DNA methylation P Lhoumaud, G Sethia, F Izzo, T Sakellaropoulos, V Snetkova, S Vidal, ... Genome biology 20, 1-12, 2019 | 36 | 2019 |
| Progestin drives breast cancer growth by inducing p21CIP1 expression through the assembly of a transcriptional complex among Stat3, progesterone receptor and ErbB-2 MCD Flaqué, R Vicario, CJ Proietti, F Izzo, R Schillaci, PV Elizalde Steroids 78 (6), 559-567, 2013 | 33 | 2013 |
| Influence of conformationally restricted pyrimidines on the activity of 10–23 DNAzymes L Robaldo, F Izzo, M Dellafiore, C Proietti, PV Elizalde, JM Montserrat, ... Bioorganic & medicinal chemistry 20 (8), 2581-2586, 2012 | 27 | 2012 |
| Mapping genotypes to chromatin accessibility profiles in single cells F Izzo, RM Myers, S Ganesan, L Mekerishvili, S Kottapalli, T Prieto, ... Nature, 1-9, 2024 | 21 | 2024 |
| Integrated Single-Cell Genotyping and Chromatin Accessibility Charts JAK2V617F Human Hematopoietic Differentiation RM Myers, F Izzo, S Kottapalli, T Prieto, A Dunbar, RL Bowman, ... BioRxiv, 2022.05. 11.491515, 2022 | 15 | 2022 |
| Jak2V617F Reversible Activation Shows Its Essential Requirement in Myeloproliferative Neoplasms AJ Dunbar, RL Bowman, YC Park, K O'Connor, F Izzo, RM Myers, ... Cancer discovery 14 (5), 737-751, 2024 | 14 | 2024 |
| Heregulin co-opts PR transcriptional action via Stat3 role as a coregulator to drive cancer growth CJ Proietti, F Izzo, MC Díaz Flaqué, R Cordo Russo, L Venturutti, ... Molecular Endocrinology 29 (10), 1468-1485, 2015 | 14 | 2015 |
| Halting ErbB-2 isoforms retrograde transport to the nucleus as a new theragnostic approach for triple-negative breast cancer S Madera, F Izzo, MF Chervo, A Dupont, VA Chiauzzi, S Bruni, E Petrillo, ... Cell Death & Disease 13 (5), 447, 2022 | 12 | 2022 |
| Canonical ErbB-2 isoform and ErbB-2 variant c located in the nucleus drive triple negative breast cancer growth MF Chervo, RI Cordo Russo, E Petrillo, F Izzo, M De Martino, N Bellora, ... Oncogene 39 (39), 6245-6262, 2020 | 12 | 2020 |
