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Douglas Micalizzi
Douglas Micalizzi
Massachusetts General Hospital
Zweryfikowany adres z partners.org
Tytuł
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Cytowane przez
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Epithelial-mesenchymal transition in cancer: parallels between normal development and tumor progression
DS Micalizzi, SM Farabaugh, HL Ford
Journal of mammary gland biology and neoplasia 15, 117-134, 2010
13972010
A conduit to metastasis: circulating tumor cell biology
DS Micalizzi, S Maheswaran, DA Haber
Genes & development 31 (18), 1827-1840, 2017
4792017
The miR-106b-25 cluster targets Smad7, activates TGF-β signaling, and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast cancer
AL Smith, R Iwanaga, DJ Drasin, DS Micalizzi, RL Vartuli, AC Tan, ...
Oncogene 31 (50), 5162-5171, 2012
3692012
Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis
RY Ebright, S Lee, BS Wittner, KL Niederhoffer, BT Nicholson, A Bardia, ...
Science 367 (6485), 1468-1473, 2020
3162020
The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-β signaling
DS Micalizzi, KL Christensen, P Jedlicka, RD Coletta, AE Barón, ...
The Journal of clinical investigation 119 (9), 2678-2690, 2009
2862009
Epithelial–mesenchymal transition in development and cancer
DS Micalizzi, HL Ford
Future oncology 5 (8), 1129-1143, 2009
1832009
Eya2 is required to mediate the pro-metastatic functions of Six1 via the induction of TGF-β signaling, epithelial–mesenchymal transition, and cancer stem cell properties
SM Farabaugh, DS Micalizzi, P Jedlicka, R Zhao, HL Ford
Oncogene 31 (5), 552-562, 2012
1612012
SIX1 induces lymphangiogenesis and metastasis via upregulation of VEGF-C in mouse models of breast cancer
CA Wang, P Jedlicka, AN Patrick, DS Micalizzi, KC Lemmer, E Deitsch, ...
The Journal of clinical investigation 122 (5), 1895-1906, 2012
1552012
Six1 overexpression in mammary cells induces genomic instability and is sufficient for malignant transformation
RD Coletta, KL Christensen, DS Micalizzi, P Jedlicka, M Varella-Garcia, ...
Cancer research 68 (7), 2204-2213, 2008
1302008
Homeoprotein Six1 increases TGF-β type I receptor and converts TGF-β signaling from suppressive to supportive for tumor growth
DS Micalizzi, CA Wang, SM Farabaugh, WP Schiemann, HL Ford
Cancer research 70 (24), 10371-10380, 2010
1292010
Expression of Six1 in luminal breast cancers predicts poor prognosis and promotes increases in tumor initiating cells by activation of extracellular signal-regulated kinase and …
R Iwanaga, CA Wang, DS Micalizzi, JC Harrell, P Jedlicka, CA Sartorius, ...
Breast Cancer Research 14, 1-14, 2012
1132012
HIF1A signaling selectively supports proliferation of breast cancer in the brain
RY Ebright, MA Zachariah, DS Micalizzi, BS Wittner, KL Niederhoffer, ...
Nature communications 11 (1), 6311, 2020
822020
Cancer metastasis through the prism of epithelial‐to‐mesenchymal transition in circulating tumor cells
DS Micalizzi, DA Haber, S Maheswaran
Molecular oncology 11 (7), 770-780, 2017
802017
Translational regulation of cancer metastasis
DS Micalizzi, RY Ebright, DA Haber, S Maheswaran
Cancer research 81 (3), 517-524, 2021
352021
A post-transcriptional program of chemoresistance by AU-rich elements and TTP in quiescent leukemic cells
S Lee, D Micalizzi, SS Truesdell, SIA Bukhari, M Boukhali, ...
Genome biology 21, 1-23, 2020
282020
Phase Ib trial to evaluate safety and anti-tumor activity of the AKT inhibitor, ipatasertib, in combination with endocrine therapy and a CDK4/6 inhibitor for patients with …
SA Wander, D Juric, JG Supko, DS Micalizzi, L Spring, N Vidula, M Beeler, ...
Journal of Clinical Oncology 38 (15_suppl), 1066-1066, 2020
202020
Identification of Somatically Acquired BRCA1/2 Mutations by cfDNA Analysis in Patients with Metastatic Breast Cancer
N Vidula, T Dubash, MS Lawrence, A Simoneau, A Niemierko, E Blouch, ...
Clinical Cancer Research 26 (18), 4852-4862, 2020
172020
A Gene Panel Associated With Abemaciclib Utility in ESR1-Mutated Breast Cancer After Prior Cyclin-Dependent Kinase 4/6-Inhibitor Progression
JO Brett, TD Dubash, GN Johnson, A Niemierko, V Mariotti, LSL Kim, J Xi, ...
JCO Precision Oncology 7, e2200532, 2023
122023
Targeting breast and pancreatic cancer metastasis using a dual-cadherin antibody
DS Micalizzi, D Che, BT Nicholson, JF Edd, N Desai, ER Lang, M Toner, ...
Proceedings of the National Academy of Sciences 119 (43), e2209563119, 2022
112022
On the trail of invasive cells in breast cancer
DS Micalizzi, S Maheswaran
Nature 554 (7692), 308-309, 2018
102018
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