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Ashot Sargsyan
Ashot Sargsyan
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Tytuł
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Liver retinol transporter and receptor for serum retinol-binding protein (RBP4)
P Alapatt, F Guo, SM Komanetsky, S Wang, J Cai, A Sargsyan, ER Díaz, ...
Journal of Biological Chemistry 288 (2), 1250-1265, 2013
1702013
Impairment of autophagy in endothelial cells prevents shear-stress-induced increases in nitric oxide bioavailability
LP Bharath, R Mueller, Y Li, T Ruan, D Kunz, R Goodrich, T Mills, ...
Canadian journal of physiology and pharmacology 92 (7), 605-612, 2014
1322014
Intestinal, but not hepatic, ChREBP is required for fructose tolerance
MS Kim, II Astapova, SN Flier, SA Hannou, L Doridot, A Sargsyan, ...
JCI insight 2 (24), e96703, 2017
1002017
Autophagy ablation in adipocytes induces insulin resistance and reveals roles for lipid peroxide and Nrf2 signaling in adipose-liver crosstalk
J Cai, KM Pires, M Ferhat, B Chaurasia, MA Buffolo, R Smalling, ...
Cell reports 25 (7), 1708-1717. e5, 2018
992018
Endothelial cell autophagy maintains shear stress–induced nitric oxide generation via glycolysis-dependent purinergic signaling to endothelial nitric oxide synthase
LP Bharath, JM Cho, SK Park, T Ruan, Y Li, R Mueller, T Bean, V Reese, ...
Arteriosclerosis, thrombosis, and vascular biology 37 (9), 1646-1656, 2017
982017
Hepatocytes are the principal source of circulating RBP4 in mice
SJ Thompson*, A Sargsyan*, SA Lee, JJ Yuen, J Cai, R Smalling, ...
Diabetes 66 (1), 58-63, 2017
872017
The incretin co-agonist tirzepatide requires GIPR for hormone secretion from human islets
K El, JD Douros, FS Willard, A Novikoff, A Sargsyan, D Perez-Tilve, ...
Nature Metabolism 5 (6), 945-954, 2023
692023
Rapid parallel measurements of macroautophagy and mitophagy in mammalian cells using a single fluorescent biosensor
A Sargsyan, J Cai, LB Fandino, ME Labasky, T Forostyan, LK Colosimo, ...
Scientific reports 5 (1), 12397, 2015
492015
Regulation of glucose production in the pathogenesis of type 2 diabetes
A Sargsyan, MA Herman
Current diabetes reports 19, 1-11, 2019
422019
HGFAC is a ChREBP-regulated hepatokine that enhances glucose and lipid homeostasis
A Sargsyan, L Doridot, SA Hannou, W Tong, H Srinivasan, R Ivison, ...
JCI insight 8 (1), e153740, 2023
202023
The intestine is a major contributor to circulating succinate in mice
W Tong, SA Hannou, Y Wang, I Astapova, A Sargsyan, R Monn, ...
The FASEB Journal 36 (10), e22546, 2022
112022
296-OR: Glucagon and Insulin Cross Talk Regulates Hepatic Glycogen Metabolism
M CAPOZZI, D BOUSLOV, A SARGSYAN, J CAMPBELL
Diabetes 73 (Supplement_1), 2024
2024
1562-P: Hepatic ChREBP-ß Overexpression Enhances Peripheral Glucose and Lipid Homeostasis Independently of FGF21
S HANNOU, A SARGSYAN, W TONG, JIE AN, CB NEWGARD, ...
Diabetes 72 (Supplement_1), 2023
2023
Metformin Impairs Intestinal Fructose Metabolism
W Tong, SA Hannou, A Sargsyan, GF Zhang, PA Grimsrud, I Astapova, ...
bioRxiv, 2023
2023
The Intestine is a Major Contributor to Circulating TCA Cycle Intermediates in Mice
W Tong, SA Hannou, Y Wang, I Astapova, A Sargsyan, R Monn, ...
bioRxiv, 2022.01. 20.477123, 2022
2022
The Intestine is a Major Contributor to Circulating Succinate in Mice
M Herman, W Tong, S Hannou, Y Wang, I Astapova, A Sargsyan, R Monn, ...
(No Title), 2022
2022
Mitochondrial Pyruvate Metabolism Induces Pseudohypoxia and Mitophagy
A Sargsyan
The University of Utah, 2017
2017
Iron Chelation Induces Hif1-alpha and Bnip3l/Nix-dependent Mitophagy
A Sargsyan, M Labasky, L Fandino, TE Graham
DIABETES 64, A488-A488, 2015
2015
Serum Retinol Binding Protein (RBP4) Is Absent from Circulation of Mice with Hepatocyte-specific Genetic Deletion of RBP4
SJ Thompson, J Cai, A Sargsyan, WS Blaner, TE Graham
DIABETES 64, A480-A481, 2015
2015
Insulin Inhibits Autophagy Independently of mTORC1 Signaling in 3T3L1 Adipocytes
J Cai, A Sargsyan, SJ Thompson, TE Graham
DIABETES 64, A481-A481, 2015
2015
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