Extracellular nicotinamide phosphoribosyltransferase (NAMPT) promotes M2 macrophage polarization in chronic lymphocytic leukemia V Audrito, S Serra, D Brusa, F Mazzola, F Arruga, T Vaisitti, M Coscia, ... Blood, The Journal of the American Society of Hematology 125 (1), 111-123, 2015 | 198 | 2015 |
Identification of a novel human nicotinamide mononucleotide adenylyltransferase N Raffaelli, L Sorci, A Amici, M Emanuelli, F Mazzola, G Magni Biochemical and biophysical research communications 297 (4), 835-840, 2002 | 186 | 2002 |
Metabolic profiling of alternative NAD biosynthetic routes in mouse tissues V Mori, A Amici, F Mazzola, M Di Stefano, L Conforti, G Magni, S Ruggieri, ... PloS one 9 (11), e113939, 2014 | 166 | 2014 |
WldS protein requires Nmnat activity and a short N-terminal sequence to protect axons in mice L Conforti, A Wilbrey, G Morreale, L Janeckova, B Beirowski, R Adalbert, ... Journal of Cell Biology 184 (4), 491-500, 2009 | 135 | 2009 |
Non-nuclear WldS determines its neuroprotective efficacy for axons and synapses in vivo B Beirowski, E Babetto, J Gilley, F Mazzola, L Conforti, L Janeckova, ... Journal of Neuroscience 29 (3), 653-668, 2009 | 122 | 2009 |
Reducing expression of NAD+ synthesizing enzyme NMNAT1 does not affect the rate of Wallerian degeneration L Conforti, L Janeckova, D Wagner, F Mazzola, L Cialabrini, M Di Stefano, ... The FEBS journal 278 (15), 2666-2679, 2011 | 102 | 2011 |
Characterization of Mycobacterium tuberculosis NAD Kinase: Functional Analysis of the Full-Length Enzyme by Site-Directed Mutagenesis N Raffaelli, L Finaurini, F Mazzola, L Pucci, L Sorci, A Amici, G Magni Biochemistry 43 (23), 7610-7617, 2004 | 73 | 2004 |
Identification of the nicotinamide salvage pathway as a new toxification route for antimetabolites D Buonvicino, F Mazzola, F Zamporlini, F Resta, G Ranieri, E Camaioni, ... Cell chemical biology 25 (4), 471-482. e7, 2018 | 71 | 2018 |
Extracellular nicotinate phosphoribosyltransferase binds Toll like receptor 4 and mediates inflammation A Managò, V Audrito, F Mazzola, L Sorci, F Gaudino, K Gizzi, N Vitale, ... Nature Communications 10 (1), 4116, 2019 | 69 | 2019 |
SIRT6 deacetylase activity regulates NAMPT activity and NAD (P)(H) pools in cancer cells G Sociali, A Grozio, I Caffa, S Schuster, P Becherini, P Damonte, L Sturla, ... The FASEB Journal 33 (3), 3704, 2018 | 68 | 2018 |
Novel assay for simultaneous measurement of pyridine mononucleotides synthesizing activities allows dissection of the NAD+ biosynthetic machinery in … F Zamporlini, S Ruggieri, F Mazzola, A Amici, G Orsomando, N Raffaelli The FEBS journal 281 (22), 5104-5119, 2014 | 61 | 2014 |
Host-Specific Modulation of the Selective Constraints Driving Human Immunodeficiency Virus Type 1env Gene Evolution P Bagnarelli, F Mazzola, S Menzo, M Montroni, L Butini, M Clementi Journal of virology 73 (5), 3764-3777, 1999 | 60 | 1999 |
Simultaneous quantitation of nicotinamide riboside, nicotinamide mononucleotide and nicotinamide adenine dinucleotide in milk by a novel enzyme-coupled assay S Ummarino, M Mozzon, F Zamporlini, A Amici, F Mazzola, G Orsomando, ... Food chemistry 221, 161-168, 2017 | 55 | 2017 |
Simultaneous single-sample determination of NMNAT isozyme activities in mouse tissues G Orsomando, L Cialabrini, A Amici, F Mazzola, S Ruggieri, L Conforti, ... PloS one 7 (12), e53271, 2012 | 42 | 2012 |
A nicotinamide phosphoribosyltransferase–GAPDH interaction sustains the stress-induced NMN/NAD+ salvage pathway in the nucleus AA Grolla, R Miggiano, D Di Marino, M Bianchi, A Gori, G Orsomando, ... Journal of Biological Chemistry 295 (11), 3635-3651, 2020 | 31 | 2020 |
Probing binding requirements of NAD kinase with modified substrate (NAD) analogues L Bonnac, L Chen, R Pathak, G Gao, Q Ming, E Bennett, K Felczak, ... Bioorganic & medicinal chemistry letters 17 (6), 1512-1515, 2007 | 30 | 2007 |
Selective inhibition of nicotinamide adenine dinucleotide kinases by dinucleoside disulfide mimics of nicotinamide adenine dinucleotide analogues R Petrelli, YY Sham, L Chen, K Felczak, E Bennett, D Wilson, C Aldrich, ... Bioorganic & medicinal chemistry 17 (15), 5656-5664, 2009 | 28 | 2009 |
The key role of the NAD biosynthetic enzyme nicotinamide mononucleotide adenylyltransferase in regulating cell functions C Fortunato, F Mazzola, N Raffaelli IUBMB life 74 (7), 562-572, 2022 | 22 | 2022 |
Molecular insights into the interaction between human nicotinamide phosphoribosyltransferase and Toll-like receptor 4 M Gasparrini, F Mazzola, M Cuccioloni, L Sorci, V Audrito, F Zamporlini, ... Journal of Biological Chemistry 298 (3), 2022 | 20 | 2022 |
Functional characterization of COG1713 (YqeK) as a novel diadenosine tetraphosphate hydrolase family G Minazzato, M Gasparrini, A Amici, M Cianci, F Mazzola, G Orsomando, ... Journal of Bacteriology 202 (10), 10.1128/jb. 00053-20, 2020 | 19 | 2020 |