Single-cell transcriptome atlas of murine endothelial cells J Kalucka, LPMH de Rooij, J Goveia, K Rohlenova, SJ Dumas, E Meta, ... Cell 180 (4), 764-779. e20, 2020 | 1039 | 2020 |
Fatty acid carbon is essential for dNTP synthesis in endothelial cells S Schoors, U Bruning, R Missiaen, KCS Queiroz, G Borgers, I Elia, ... Nature 520 (7546), 192-197, 2015 | 622 | 2015 |
Inhibition of the glycolytic activator PFKFB3 in endothelium induces tumor vessel normalization, impairs metastasis, and improves chemotherapy AR Cantelmo, LC Conradi, A Brajic, J Goveia, J Kalucka, A Pircher, ... Cancer cell 30 (6), 968-985, 2016 | 618 | 2016 |
Partial and transient reduction of glycolysis by PFKFB3 blockade reduces pathological angiogenesis S Schoors, K De Bock, AR Cantelmo, M Georgiadou, B Ghesquière, ... Cell metabolism 19 (1), 37-48, 2014 | 565 | 2014 |
Macrophage metabolism controls tumor blood vessel morphogenesis and metastasis M Wenes, M Shang, M Di Matteo, J Goveia, R Martín-Pérez, J Serneels, ... Cell metabolism 24 (5), 701-715, 2016 | 461 | 2016 |
An integrated gene expression landscape profiling approach to identify lung tumor endothelial cell heterogeneity and angiogenic candidates J Goveia, K Rohlenova, F Taverna, L Treps, LC Conradi, A Pircher, ... Cancer cell 37 (1), 21-36. e13, 2020 | 407 | 2020 |
The role of fatty acid β-oxidation in lymphangiogenesis BW Wong, X Wang, A Zecchin, B Thienpont, I Cornelissen, J Kalucka, ... Nature 542 (7639), 49-54, 2017 | 316 | 2017 |
Dual inhibition of Ang-2 and VEGF receptors normalizes tumor vasculature and prolongs survival in glioblastoma by altering macrophages TE Peterson, ND Kirkpatrick, Y Huang, CT Farrar, KA Marijt, J Kloepper, ... Proceedings of the National Academy of Sciences 113 (16), 4470-4475, 2016 | 308 | 2016 |
Role of glutamine and interlinked asparagine metabolism in vessel formation H Huang, S Vandekeere, J Kalucka, L Bierhansl, A Zecchin, U Brüning, ... The EMBO journal 36 (16), 2334-2352, 2017 | 278 | 2017 |
Quiescent endothelial cells upregulate fatty acid β-oxidation for vasculoprotection via redox homeostasis J Kalucka, L Bierhansl, NV Conchinha, R Missiaen, I Elia, U Brüning, ... Cell metabolism 28 (6), 881-894. e13, 2018 | 262 | 2018 |
Increase in tumor-associated macrophages after antiangiogenic therapy is associated with poor survival among patients with recurrent glioblastoma C Lu-Emerson, M Snuderl, ND Kirkpatrick, J Goveia, C Davidson, ... Neuro-oncology 15 (8), 1079-1087, 2013 | 248 | 2013 |
Single-cell RNA sequencing maps endothelial metabolic plasticity in pathological angiogenesis K Rohlenova, J Goveia, M García-Caballero, A Subramanian, J Kalucka, ... Cell metabolism 31 (4), 862-877. e14, 2020 | 243 | 2020 |
Principles of targeting endothelial cell metabolism to treat angiogenesis and endothelial cell dysfunction in disease J Goveia, P Stapor, P Carmeliet EMBO molecular medicine 6 (9), 1105-1120, 2014 | 223 | 2014 |
Impairment of angiogenesis by fatty acid synthase inhibition involves mTOR malonylation U Bruning, F Morales-Rodriguez, J Kalucka, J Goveia, F Taverna, ... Cell metabolism 28 (6), 866-880. e15, 2018 | 219 | 2018 |
Role of glutamine synthetase in angiogenesis beyond glutamine synthesis G Eelen, C Dubois, AR Cantelmo, J Goveia, U Brüning, M DeRan, ... Nature 561 (7721), 63-69, 2018 | 199 | 2018 |
HIF-1α promotes glutamine-mediated redox homeostasis and glycogen-dependent bioenergetics to support postimplantation bone cell survival S Stegen, N van Gastel, G Eelen, B Ghesquière, F D’Anna, B Thienpont, ... Cell metabolism 23 (2), 265-279, 2016 | 181 | 2016 |
The multifaceted activity of VEGF in angiogenesis–Implications for therapy responses S Moens, J Goveia, PC Stapor, AR Cantelmo, P Carmeliet Cytokine & growth factor reviews 25 (4), 473-482, 2014 | 172 | 2014 |
Single-cell RNA sequencing reveals renal endothelium heterogeneity and metabolic adaptation to water deprivation SJ Dumas, E Meta, M Borri, J Goveia, K Rohlenova, NV Conchinha, ... Journal of the American Society of Nephrology 31 (1), 118-138, 2020 | 167 | 2020 |
Serine synthesis via PHGDH is essential for heme production in endothelial cells S Vandekeere, C Dubois, J Kalucka, MR Sullivan, M García-Caballero, ... Cell metabolism 28 (4), 573-587. e13, 2018 | 166 | 2018 |
Angiogenesis revisited–role and therapeutic potential of targeting endothelial metabolism P Stapor, X Wang, J Goveia, S Moens, P Carmeliet Journal of cell science 127 (20), 4331-4341, 2014 | 124 | 2014 |