Direct asymmetric hydrosilylation of indoles: Combined Lewis base and brønsted acid activation YC Xiao, C Wang, Y Yao, J Sun, YC Chen Angewandte Chemie 45 (123), 10849-10852, 2011 | 141 | 2011 |
Lewis acid catalyzed intramolecular direct ene reaction of indoles B Han, YC Xiao, Y Yao, YC Chen Angewandte Chemie International Edition 52 (49), 10189-10191, 2010 | 132 | 2010 |
Asymmetric Michael addition of γ, γ-disubstituted α, β-unsaturated aldehydes to nitroolefins via dienamine catalysis B Han, YC Xiao, ZQ He, YC Chen Organic Letters 11 (20), 4660-4663, 2009 | 111 | 2009 |
Asymmetric dearomatic Diels–Alder reactions of diverse heteroarenes via π-system activation YC Xiao, CZ Yue, PQ Chen, YC Chen Organic letters 16 (12), 3208-3211, 2014 | 76 | 2014 |
Selective inhibition of Ph-positive ALL cell growth through kinase-dependent and-independent effects by CDK6-specific PROTACs M De Dominici, P Porazzi, Y Xiao, A Chao, HY Tang, G Kumar, P Fortina, ... Blood, The Journal of the American Society of Hematology 135 (18), 1560-1573, 2020 | 71 | 2020 |
Remote Enantioselective Friedel–Crafts Alkylations of Furans through HOMO Activation JL Li, CZ Yue, PQ Chen, YC Xiao, YC Chen Angewandte Chemie 126 (21), 5553-5556, 2014 | 69 | 2014 |
Asymmetric Diels–Alder Reaction of 2-Methyl-3-indolylmethanols via in Situ Generation of o-Quinodimethanes YC Xiao, QQ Zhou, L Dong, TY Liu, YC Chen Organic letters 14 (23), 5940-5943, 2012 | 69 | 2012 |
Targeted MDM2 degradation reveals a new vulnerability for p53-inactivated triple-negative breast cancer CM Adams, R Mitra, Y Xiao, P Michener, J Palazzo, A Chao, J Gour, ... Cancer discovery 13 (5), 1210-1229, 2023 | 61 | 2023 |
Enantioselective Formal [3+ 3] Cycloadditions of Ketones and Cyclic 1‐Azadienes by Cascade Enamine–Enamine Catalysis XL He, YC Xiao, W Du, YC Chen Chemistry–A European Journal 21 (8), 3443-3448, 2015 | 48 | 2015 |
Thiourea-Catalyzed Asymmetric Mannich-Type Reactions B Han, JL Li, YC Xiao, SL Zhou, YC Chen Current Organic Chemistry 15 (24), 4128-4143, 2011 | 46 | 2011 |
Exploring structural determinants of inhibitor affinity and selectivity in complexes with histone deacetylase 6 JD Osko, NJ Porter, PA Narayana Reddy, YC Xiao, J Rokka, M Jung, ... Journal of medicinal chemistry 63 (1), 295-308, 2019 | 42 | 2019 |
Trienamine catalysis with linear deconjugated 3, 5-dienones PQ Chen, YC Xiao, CZ Yue, YC Chen Organic Chemistry Frontiers 1 (5), 490-493, 2014 | 41 | 2014 |
Silaborative carbocyclizations of 1, 7-enynes. Diastereoselective preparation of chromane derivatives YC Xiao, C Moberg Organic letters 18 (2), 308-311, 2016 | 37 | 2016 |
Asymmetric Diels–Alder reactions of 2, 4, 6‐trienals via tetraenamine catalysis QQ Zhou, YC Xiao, X Yuan, YC Chen Asian Journal of Organic Chemistry 3 (4), 545-549, 2014 | 37 | 2014 |
Identification of a novel allosteric modulator of the human dopamine transporter S Aggarwal, X Liu, C Rice, P Menell, PJ Clark, N Paparoidamis, Y Xiao, ... ACS chemical neuroscience 10 (8), 3718-3730, 2019 | 31 | 2019 |
Aminocatalytic asymmetric Diels–Alder reaction of phosphorus dienophiles and 2, 4-dienals QQ Zhou, X Yuan, YC Xiao, L Dong, YC Chen Tetrahedron 69 (48), 10369-10374, 2013 | 27 | 2013 |
Discovery of 3-aryl substituted benzoxaboroles as broad-spectrum inhibitors of serine-and metallo-β-lactamases YH Yan, ZF Li, XL Ning, J Deng, JL Yu, Y Luo, Z Wang, G Li, GB Li, ... Bioorganic & Medicinal Chemistry Letters 41, 127956, 2021 | 20 | 2021 |
Unified strategy to amphenicol antibiotics: asymmetric synthesis of (−)-chloramphenicol,(−)-azidamphenicol, and (+)-thiamphenicol and its (+)-3-floride J Liu, Y Li, M Ke, M Liu, P Zhan, YC Xiao, F Chen The Journal of Organic Chemistry 85 (23), 15360-15367, 2020 | 20 | 2020 |
Hydroxyapatite nanoparticles promote TLR4 agonist-mediated anti-tumor immunity through synergically enhanced macrophage polarization R Wang, Y Hua, H Wu, J Wang, Y Xiao, X Chen, Q Ao, Q Zeng, X Zhu, ... Acta Biomaterialia 164, 626-640, 2023 | 18 | 2023 |
Targeting metalloenzymes by boron-containing metal-binding pharmacophores YC Xiao, JL Yu, QQ Dai, G Li, GB Li Journal of Medicinal Chemistry 64 (24), 17706-17727, 2021 | 16 | 2021 |