Tumor cell-intrinsic factors underlie heterogeneity of immune cell infiltration and response to immunotherapy J Li, KT Byrne, F Yan, T Yamazoe, Z Chen, T Baslan, LP Richman, JH Lin, ... Immunity 49 (1), 178-193. e7, 2018 | 651 | 2018 |
Hypoxia-dependent modification of collagen networks promotes sarcoma metastasis TSK Eisinger-Mathason, M Zhang, Q Qiu, N Skuli, MS Nakazawa, ... Cancer discovery 3 (10), 1190-1205, 2013 | 291 | 2013 |
Tumor-derived retinoic acid regulates intratumoral monocyte differentiation to promote immune suppression S Devalaraja, TKJ To, IW Folkert, R Natesan, MZ Alam, M Li, Y Tada, ... Cell 180 (6), 1098-1114. e16, 2020 | 218 | 2020 |
Codependent functions of RSK2 and the apoptosis-promoting factor TIA-1 in stress granule assembly and cell survival TSK Eisinger-Mathason, J Andrade, AL Groehler, DE Clark, ... Molecular cell 31 (5), 722-736, 2008 | 185 | 2008 |
Intratumoral oxygen gradients mediate sarcoma cell invasion DM Lewis, KM Park, V Tang, Y Xu, K Pak, TSK Eisinger-Mathason, ... Proceedings of the National Academy of Sciences 113 (33), 9292-9297, 2016 | 124 | 2016 |
Deregulation of the Hippo pathway in soft-tissue sarcoma promotes FOXM1 expression and tumorigenesis TSK Eisinger-Mathason, V Mucaj, KM Biju, MS Nakazawa, M Gohil, ... Proceedings of the National Academy of Sciences 112 (26), E3402-E3411, 2015 | 115 | 2015 |
Sustained activation of the HER1–ERK1/2–RSK signaling pathway controls myoepithelial cell fate in human mammary tissue L Pasic, TSK Eisinger-Mathason, BT Velayudhan, CA Moskaluk, ... Genes & Development 25 (15), 1641-1653, 2011 | 86 | 2011 |
Inhibition of hypoxia-inducible factors limits tumor progression in a mouse model of colorectal cancer JES Shay, HZ Imtiyaz, S Sivanand, AC Durham, N Skuli, S Hsu, V Mucaj, ... Carcinogenesis 35 (5), 1067-1077, 2014 | 82 | 2014 |
Epigenetic re-expression of HIF-2α suppresses soft tissue sarcoma growth MS Nakazawa, TSK Eisinger-Mathason, N Sadri, JD Ochocki, TPF Gade, ... Nature communications 7 (1), 10539, 2016 | 81 | 2016 |
RSK in tumorigenesis: connections to steroid signaling TSK Eisinger-Mathason, J Andrade, DA Lannigan Steroids 75 (3), 191-202, 2010 | 70 | 2010 |
MicroRNA-124 expression counteracts pro-survival stress responses in glioblastoma V Mucaj, SS Lee, N Skuli, DN Giannoukos, B Qiu, TSK Eisinger-Mathason, ... Oncogene 34 (17), 2204-2214, 2015 | 68 | 2015 |
Use of an anti-viral drug, Ribavirin, as an anti-glioblastoma therapeutic F Volpin, J Casaos, J Sesen, A Mangraviti, J Choi, N Gorelick, J Frikeche, ... Oncogene 36 (21), 3037-3047, 2017 | 57 | 2017 |
YAP1-mediated suppression of USP31 enhances NFκB activity to promote sarcomagenesis S Ye, MA Lawlor, A Rivera-Reyes, S Egolf, S Chor, K Pak, GE Ciotti, ... Cancer research 78 (10), 2705-2720, 2018 | 56 | 2018 |
Overcoming evasive resistance from vascular endothelial growth factor a inhibition in sarcomas by genetic or pharmacologic targeting of hypoxia‐inducible factor 1α YJ Kim, HJ Lee, TM Kim, TSK Eisinger‐Mathason, AY Zhang, B Schmidt, ... International journal of cancer 132 (1), 29-41, 2013 | 51 | 2013 |
The aryl hydrocarbon receptor nuclear translocator is an essential regulator of murine hematopoietic stem cell viability BL Krock, TS Eisinger-Mathason, DN Giannoukos, JE Shay, M Gohil, ... Blood, The Journal of the American Society of Hematology 125 (21), 3263-3272, 2015 | 49 | 2015 |
TGFβ and hippo pathways cooperate to enhance sarcomagenesis and metastasis through the hyaluronan-mediated motility receptor (HMMR) S Ye, Y Liu, AM Fuller, R Katti, GE Ciotti, S Chor, MZ Alam, S Devalaraja, ... Molecular Cancer Research 18 (4), 560-573, 2020 | 44 | 2020 |
YAP1 enhances NF-κB-dependent and independent effects on clock-mediated unfolded protein responses and autophagy in sarcoma A Rivera-Reyes, S Ye, G E. Marino, S Egolf, G E. Ciotti, S Chor, Y Liu, ... Cell death & disease 9 (11), 1108, 2018 | 43 | 2018 |
Targeting the Hippo pathway: Clinical implications and therapeutics S Ye, TSK Eisinger-Mathason Pharmacological research 103, 270-278, 2016 | 43 | 2016 |
Hypoxia-activated chemotherapeutic TH-302 enhances the effects of VEGF-A inhibition and radiation on sarcomas C Yoon, HJ Lee, DJ Park, YJ Lee, WD Tap, TSK Eisinger-Mathason, ... British Journal of Cancer 113 (1), 46-56, 2015 | 36 | 2015 |
A feedback loop between hypoxia and matrix stress relaxation increases oxygen-axis migration and metastasis in sarcoma DM Lewis, H Pruitt, N Jain, M Ciccaglione, JM McCaffery, Z Xia, K Weber, ... Cancer research 79 (8), 1981-1995, 2019 | 31 | 2019 |