| Aromatic Spiroketal Bisphosphine Ligands: Palladium‐Catalyzed Asymmetric Allylic Amination of Racemic Morita–Baylis–Hillman Adducts X Wang, F Meng, Y Wang, Z Han, YJ Chen, L Liu, Z Wang, K Ding Angewandte Chemie International Edition 37 (51), 9276-9282, 2012 | 223 | 2012 |
| Cancer selective target degradation by folate-caged PROTACs J Liu, H Chen, Y Liu, Y Shen, F Meng, HU Kaniskan, J Jin, W Wei Journal of the American Chemical Society 143 (19), 7380-7387, 2021 | 195 | 2021 |
| Discovery of potent and selective epidermal growth factor receptor (EGFR) bifunctional small-molecule degraders M Cheng, X Yu, K Lu, L Xie, L Wang, F Meng, X Han, X Chen, J Liu, ... Journal of medicinal chemistry 63 (3), 1216-1232, 2020 | 149 | 2020 |
| Harnessing the E3 ligase KEAP1 for targeted protein degradation J Wei, F Meng, KS Park, H Yim, J Velez, P Kumar, L Wang, L Xie, H Chen, ... Journal of the American Chemical Society 143 (37), 15073-15083, 2021 | 98 | 2021 |
| Palladium‐Catalyzed Asymmetric Construction of Vicinal Tertiary and All‐Carbon Quaternary Stereocenters by Allylation of β‐Ketocarbonyls with Morita–Baylis–Hillman Adducts J Liu, Z Han, X Wang, F Meng, Z Wang, K Ding Angewandte Chemie International Edition 56 (18), 5050-5054, 2017 | 81 | 2017 |
| A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells C Xu, F Meng, KS Park, AJ Storey, W Gong, YH Tsai, E Gibson, SD Byrum, ... Cell chemical biology 29 (3), 386-397. e9, 2022 | 46 | 2022 |
| Discovery of a first-in-class protein arginine methyltransferase 6 (PRMT6) covalent inhibitor Y Shen, F Li, MM Szewczyk, L Halabelian, KS Park, I Chau, A Dong, ... Journal of medicinal chemistry 63 (10), 5477-5487, 2020 | 40 | 2020 |
| Discovery of a first-in-class degrader for nuclear receptor binding SET domain protein 2 (NSD2) and Ikaros/Aiolos F Meng, C Xu, KS Park, HU Kaniskan, GG Wang, J Jin Journal of medicinal chemistry 65 (15), 10611-10625, 2022 | 35 | 2022 |
| A first-in-class, highly selective and cell-active allosteric inhibitor of protein arginine methyltransferase 6 Y Shen, F Li, MM Szewczyk, L Halabelian, I Chau, MS Eram, C Dela Sena, ... Journal of medicinal chemistry 64 (7), 3697-3706, 2021 | 25 | 2021 |
| Quantum computing-enhanced algorithm unveils novel inhibitors for KRAS MG Vakili, C Gorgulla, AK Nigam, D Bezrukov, D Varoli, A Aliper, ... arXiv preprint arXiv:2402.08210, 2024 | 10 | 2024 |
| Generation of host-directed and virus-specific antivirals using targeted protein degradation promoted by small molecules and viral RNA mimics N Zhao, JSY Ho, F Meng, S Zheng, AP Kurland, L Tian, M Rea-Moreno, ... Cell Host & Microbe 31 (7), 1154-1169. e10, 2023 | 10 | 2023 |
| SOX11 inhibitors are cytotoxic in mantle cell lymphoma SS Jatiani, S Christie, VV Leshchenko, R Jain, A Kapoor, P Bisignano, ... Clinical Cancer Research 27 (16), 4652-4663, 2021 | 10 | 2021 |
| Discovery of macrocyclic CDK2/4/6 inhibitors with improved potency and DMPK properties through a highly efficient macrocyclic drug design platform F Meng, J Liu, Z Cao, J Yu, B Steurer, Y Yang, Y Wang, X Cai, M Zhang, ... Bioorganic Chemistry 146, 107285, 2024 | 5 | 2024 |
| Discovery of 3-hydroxymethyl-azetidine derivatives as potent polymerase theta inhibitors Y Wang, C Wang, J Liu, D Sun, F Meng, M Zhang, A Aliper, F Ren, ... Bioorganic & Medicinal Chemistry 103, 117662, 2024 | 5 | 2024 |
| A first-in-class, highly selective and cell-active allosteric inhibitor of protein arginine methyltransferase 6 (PRMT6) Y Shen, F Li, MM Szewczyk, L Halebelian, I Chau, MS Eram, CD Seña, ... bioRxiv, 2020.12. 04.412569, 2020 | 2 | 2020 |
| Discovery of Pyrrolopyrazine Carboxamide Derivatives as Potent and Selective FGFR2/3 Inhibitors that Overcome Mutant Resistance Y Wang, Y Zhang, J Liu, J Zhao, C Wang, F Meng, X Cai, M Zhang, ... Journal of Medicinal Chemistry, 2025 | | 2025 |
| Quantum-computing-enhanced algorithm unveils potential KRAS inhibitors M Ghazi Vakili, C Gorgulla, J Snider, AK Nigam, D Bezrukov, D Varoli, ... Nature Biotechnology, 1-6, 2025 | | 2025 |
| Discovery of pyrrolopyrimidinone derivatives as potent PKMYT1 inhibitors for the treatment of cancer C Wang, Y Wang, F Meng, T Liu, X Wang, X Cai, M Zhang, A Aliper, F Ren, ... European Journal of Medicinal Chemistry 281, 117025, 2025 | | 2025 |
| Novel Insights into SOX11 Modulation of BCR Signaling and Targeting of BTK Resistance RP Dutta, HH Lee, RP Shukla, VV Leshchenko, F Meng, F Yan, Y Liu, ... Blood 144, 1402, 2024 | | 2024 |
| CBL-B inhibitors and methods of uses thereof X Ding, J Liu, F Meng, F Ren, Y Wang WO Patent WO2024131939A1, 2024 | | 2024 |