NF-κB restricts inflammasome activation via elimination of damaged mitochondria Z Zhong, A Umemura, E Sanchez-Lopez, S Liang, S Shalapour, J Wong, ... Cell 164 (5), 896-910, 2016 | 1115 | 2016 |
New mitochondrial DNA synthesis enables NLRP3 inflammasome activation Z Zhong, S Liang, E Sanchez-Lopez, F He, S Shalapour, X Lin, J Wong, ... Nature 560 (7717), 198-203, 2018 | 998 | 2018 |
TGF-β signaling in vascular fibrosis M Ruiz-Ortega, J Rodríguez-Vita, E Sanchez-Lopez, G Carvajal, J Egido Cardiovascular research 74 (2), 196-206, 2007 | 708 | 2007 |
Autophagy, inflammation, and immunity: a troika governing cancer and its treatment Z Zhong, E Sanchez-Lopez, M Karin Cell 166 (2), 288-298, 2016 | 604 | 2016 |
Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy S Shalapour, J Font-Burgada, G Di Caro, Z Zhong, E Sanchez-Lopez, ... Nature 521 (7550), 94-98, 2015 | 582 | 2015 |
Synovial inflammation in osteoarthritis progression E Sanchez-Lopez, R Coras, A Torres, NE Lane, M Guma Nature Reviews Rheumatology 18 (5), 258-275, 2022 | 567 | 2022 |
Angiotensin II: a key factor in the inflammatory and fibrotic response in kidney diseases M Ruiz-Ortega, M Rupérez, V Esteban, J Rodríguez-Vita, ... Nephrology Dialysis Transplantation 21 (1), 16-20, 2006 | 471 | 2006 |
Angiotensin II activates the Smad pathway in vascular smooth muscle cells by a transforming growth factor-β–independent mechanism J Rodríguez-Vita, E Sánchez-López, V Esteban, M Rupérez, J Egido, ... Circulation 111 (19), 2509-2517, 2005 | 428 | 2005 |
Interleukin-17 receptor a signaling in transformed enterocytes promotes early colorectal tumorigenesis K Wang, MK Kim, G Di Caro, J Wong, S Shalapour, J Wan, W Zhang, ... Immunity 41 (6), 1052-1063, 2014 | 367 | 2014 |
Oxidized DNA fragments exit mitochondria via mPTP-and VDAC-dependent channels to activate NLRP3 inflammasome and interferon signaling H Xian, K Watari, E Sanchez-Lopez, J Offenberger, J Onyuru, H Sampath, ... Immunity 55 (8), 1370-1385. e8, 2022 | 359 | 2022 |
Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation H Xian, Y Liu, AR Nilsson, R Gatchalian, TR Crother, WG Tourtellotte, ... Immunity 54 (7), 1463-1477. e11, 2021 | 281 | 2021 |
Renal and vascular hypertension-induced inflammation: role of angiotensin II M Ruiz-Ortega, V Esteban, M Rupérez, E Sánchez-López, ... Current Opinion in Nephrology and Hypertension 15 (2), 159-166, 2006 | 217 | 2006 |
Choline uptake and metabolism modulate macrophage IL-1β and IL-18 production E Sanchez-Lopez, Z Zhong, A Stubelius, SR Sweeney, LM Booshehri, ... Cell metabolism 29 (6), 1350-1362. e7, 2019 | 199 | 2019 |
Autophagy, NLRP3 inflammasome and auto-inflammatory/immune diseases. Z Zhong, E Sanchez-Lopez, M Karin Clinical and experimental rheumatology 34 (4 Suppl 98), 12-16, 2016 | 187 | 2016 |
Endothelin-1, via ETA Receptor and Independently of Transforming Growth Factor-β, Increases the Connective Tissue Growth Factor in Vascular Smooth Muscle … J Rodriguez-Vita, M Ruiz-Ortega, M Rupérez, V Esteban, ... Circulation research 97 (2), 125-134, 2005 | 177 | 2005 |
Targeting colorectal cancer via its microenvironment by inhibiting IGF-1 receptor-insulin receptor substrate and STAT3 signaling. E Sanchez-Lopez, E Flashner-Abramson, S Shalapour, Z Zhong, ... Oncogene. 35 (20), 2634-44, 2016 | 176 | 2016 |
HMG-CoA reductase inhibitors decrease angiotensin II–induced vascular fibrosis: role of RhoA/ROCK and MAPK pathways M Rupérez, R Rodrigues-Díez, LM Blanco-Colio, E Sánchez-López, ... Hypertension 50 (2), 377-383, 2007 | 170 | 2007 |
Angiotensin II activates the Smad pathway during epithelial mesenchymal transdifferentiation G Carvajal, J Rodriguez-Vita, R Rodrigues-Diez, E Sanchez-Lopez, ... Kidney international 74 (5), 585-595, 2008 | 169 | 2008 |
Hexokinase 2 as a novel selective metabolic target for rheumatoid arthritis MF Bustamante, PG Oliveira, R Garcia-Carbonell, AP Croft, JM Smith, ... Annals of the rheumatic diseases 77 (11), 1636-1643, 2018 | 163 | 2018 |
CTGF promotes inflammatory cell infiltration of the renal interstitium by activating NF-κB E Sanchez-Lopez, S Rayego, R Rodrigues-Diez, JS Rodriguez, ... Journal of the American Society of Nephrology 20 (7), 1513-1526, 2009 | 147 | 2009 |