Identification of novel inhibitors for TNFα, TNFR1 and TNFα-TNFR1 complex using pharmacophore-based approaches MS Saddala, H Huang Journal of translational medicine 17, 1-16, 2019 | 57 | 2019 |
2-Amino-2,3-dihydro-1H-2λ5-[1,3,2]diazaphospholo[4,5-b]pyridin-2-one-based urea and thiourea derivatives: synthesis, molecular docking study and evaluation … SR Devineni, M Golla, NR Chamarthi, B Meriga, MS Saddala, ... Medicinal Chemistry Research 25, 751-768, 2016 | 50 | 2016 |
Molecular docking studies of angiogenesis target protein HIF-1α and genistein in breast cancer V Mukund, MS Saddala, B Farran, M Mannavarapu, A Alam, GP Nagaraju Gene 701, 169-172, 2019 | 49 | 2019 |
Novel 1, 4-dihydropyridines for L-type calcium channel as antagonists for cadmium toxicity MS Saddala, R Kandimalla, PJ Adi, SS Bhashyam, UR Asupatri Scientific reports 7 (1), 45211, 2017 | 36 | 2017 |
Discovery of novel L-type voltage-gated calcium channel blockers and application for the prevention of inflammation and angiogenesis MS Saddala, A Lennikov, A Mukwaya, Y Yang, MA Hill, N Lagali, ... Journal of neuroinflammation 17, 1-23, 2020 | 35 | 2020 |
Transcriptome-wide analysis of differentially expressed chemokine receptors, SNPs, and SSRs in the age-related macular degeneration MS Saddala, A Lennikov, A Mukwaya, L Fan, Z Hu, H Huang Human genomics 13, 1-14, 2019 | 33 | 2019 |
Molecular docking based screening of a simulated HIF-1 protein model for potential inhibitors MS Latha, MS Saddala Bioinformation 13 (11), 388, 2017 | 31 | 2017 |
Small molecule tyrosine kinase inhibitors and pancreatic cancer—Trials and troubles BVKS Lakkakula, B Farran, S Lakkakula, S Peela, NS Yarla, ... Seminars in cancer biology 56, 149-167, 2019 | 30 | 2019 |
Discovery of small molecules through pharmacophore modeling, docking and molecular dynamics simulation against Plasmodium vivax Vivapain-3 (VP-3) MS Saddala, PJ Adi Heliyon 4 (5), 2018 | 26 | 2018 |
Sulfonamides and carbamates of 3-fluoro-4-morpholinoaniline (linezolid intermediate): synthesis, antimicrobial activity and molecular docking study DB Janakiramudu, DS Rao, C Srikanth, MS Saddala, PS Murthy, ... Research on Chemical Intermediates, 1-21, 2017 | 25 | 2017 |
Autoimmune-mediated retinopathy in CXCR5-deficient mice as the result of age-related macular degeneration associated proteins accumulation A Lennikov, MS Saddala, A Mukwaya, S Tang, H Huang Frontiers in immunology 10, 1903, 2019 | 24 | 2019 |
Placental growth factor negatively regulates retinal endothelial cell barrier function through suppression of glucose-6-phosphate dehydrogenase and antioxidant defense systems H Huang, A Lennikov, MS Saddala, D Gozal, DJ Grab, A Khalyfa, L Fan The FASEB Journal 33 (12), 13695, 2019 | 22 | 2019 |
Proteomics reveals ablation of PlGF increases antioxidant and neuroprotective proteins in the diabetic mouse retina MS Saddala, A Lennikov, DJ Grab, GS Liu, S Tang, H Huang Scientific reports 8 (1), 16728, 2018 | 22 | 2018 |
Targeting STAT proteins via computational analysis in colorectal cancer B Dariya, S Muppala, G Srivani, S Momin, A Alam, MS Saddala Molecular and Cellular Biochemistry 476, 165-174, 2021 | 21 | 2021 |
Discovery of small-molecule activators for glucose-6-phosphate dehydrogenase (G6PD) using machine learning approaches MS Saddala, A Lennikov, H Huang International journal of molecular sciences 21 (4), 1523, 2020 | 18 | 2020 |
Transcriptome-wide analysis reveals core sets of transcriptional regulators of sensome and inflammation genes in retinal microglia MS Saddala, X Yang, S Tang, H Huang Genomics 113 (5), 3058-3071, 2021 | 16 | 2021 |
Synergistic interactions of PlGF and VEGF contribute to blood-retinal barrier breakdown through canonical NFκB activation A Lennikov, A Mukwaya, L Fan, MS Saddala, S De Falco, H Huang Experimental cell research 397 (2), 112347, 2020 | 16 | 2020 |
In Silico drug design and molecular docking studies of potent Inhibitors against Cathepsin-L (Ctsl) for SARS disease MS Saddala, JAP Kiran, UA Rani J Res Development 4 (145), 2, 2016 | 16 | 2016 |
Aryl/heteroaryl substituted celecoxib derivatives as COX-2 inhibitors: Synthesis, anti-inflammatory activity and molecular docking studies G Madhava, K V Ramana, S M Sudhana, D S Rao, K H Kumar, ... Medicinal Chemistry 13 (5), 484-497, 2017 | 15 | 2017 |
Synthesis and evaluation of urea and thiourea derivatives of lopinavir intermediate as potent antimicrobial, antioxidant agents and molecular docking studies against Staphopain H Sudhamani, SK Thaslim Basha, S Adam, S Madhusudhana, ... Research on Chemical Intermediates 43, 103-120, 2017 | 15 | 2017 |