Alkyl 4-chlorobenzoyloxycarbamates as highly effective nitrogen source reagents for the base-free, intermolecular aminohydroxylation reaction L Harris, SPH Mee, RH Furneaux, GJ Gainsford, A Luxenburger The Journal of organic chemistry 76 (2), 358-372, 2011 | 57 | 2011 |
Optimized 4, 5-diarylimidazoles as potent/selective inhibitors of protein kinase CK1δ and their structural relation to p38α MAPK J Halekotte, L Witt, C Ianes, M Krüger, M Bührmann, D Rauh, C Pichlo, ... molecules 22 (4), 522, 2017 | 47 | 2017 |
Steady-State and Pre-steady-State Kinetic Analysis of Mycobacterium smegmatis Cysteine Ligase (MshC) Fan, A Luxenburger, GF Painter, JS Blanchard Biochemistry 46 (40), 11421-11429, 2007 | 34 | 2007 |
A novel class of potent nonglycosidic and nonpeptidic pan-selectin inhibitors HK Ulbrich, A Luxenburger, P Prech, EE Eriksson, O Soehnlein, P Rotzius, ... Journal of medicinal chemistry 49 (20), 5988-5999, 2006 | 34 | 2006 |
Studies toward the total synthesis of dumsin. 2. A second generation approach resulting in enantioselective construction of a functionalized ABC subunit of the … LA Paquette, Y Hu, A Luxenburger, RL Bishop The Journal of Organic Chemistry 72 (1), 209-222, 2007 | 25 | 2007 |
Alkali metal counterion control of enolate protonation stereoselectivity Y Hu, RL Bishop, A Luxenburger, S Dong, LA Paquette Organic Letters 8 (13), 2735-2737, 2006 | 20 | 2006 |
Tight binding enantiomers of pre-clinical drug candidates GB Evans, SA Cameron, A Luxenburger, R Guan, J Suarez, K Thomas, ... Bioorganic & medicinal chemistry 23 (17), 5326-5333, 2015 | 18 | 2015 |
Design, synthesis and biological evaluation of isoxazole-based CK1 inhibitors modified with chiral pyrrolidine scaffolds A Luxenburger, D Schmidt, C Ianes, C Pichlo, M Krüger, T von Drathen, ... Molecules 24 (5), 873, 2019 | 17 | 2019 |
A high-throughput screen to identify novel synthetic lethal compounds for the treatment of E-cadherin-deficient cells H Beetham, A Chen, BJ Telford, A Single, KE Jarman, K Lackovic, ... Scientific reports 9 (1), 12511, 2019 | 15 | 2019 |
The synthesis of carnosol derivatives A Luxenburger Tetrahedron 59 (18), 3297-3305, 2003 | 14 | 2003 |
Synthesis of 12β-methyl-18-nor-avicholic acid analogues as potential TGR5 agonists EM Ure, LD Harris, SA Cameron, A Weymouth-Wilson, RH Furneaux, ... Organic & Biomolecular Chemistry 20 (17), 3511-3527, 2022 | 8 | 2022 |
Enantioselective Stereodivergent Synthesis of Jaspine B and 4-epi-Jaspine B from Axially Chiral Allenols H Alnazer, T Castellan, Y Salma, Y Génisson, S Ballereau Synlett 30 (02), 185-188, 2019 | 8 | 2019 |
Synthesis and characterization of transition-state analogue inhibitors against human DNA methyltransferase 1 F Lamiable-Oulaidi, RK Harijan, KJ Shaffer, DR Crump, Y Sun, Q Du, ... Journal of medicinal chemistry 65 (7), 5462-5494, 2022 | 7 | 2022 |
Characterization of a computerized assay for rapid and easy determination of leukocyte adhesion to endothelial cells H Ulbrich, P Prech, A Luxenburger, G Dannhardt Biological and Pharmaceutical Bulletin 28 (4), 718-724, 2005 | 7 | 2005 |
Synthesis of 12β-Methyl-18-nor-bile Acids A Luxenburger, LD Harris, EM Ure, RA Landaeta Aponte, AD Woolhouse, ... ACS omega 6 (38), 25019-25039, 2021 | 6 | 2021 |
Synthesis of novel C/D ring modified bile acids RA Landaeta Aponte, A Luxenburger, SA Cameron, A Weymouth-Wilson, ... Molecules 27 (7), 2364, 2022 | 5 | 2022 |
3α,7-Dihydroxy-14(13→12)abeo-5β,12α(H),13β(H)-cholan-24-oic Acids Display Neuroprotective Properties in Common Forms of Parkinson’s Disease A Luxenburger, H Clemmens, C Hastings, LD Harris, EM Ure, ... Biomolecules 13 (1), 76, 2022 | 4 | 2022 |
Discovery of AL-GDa62 as a potential synthetic lethal lead for the treatment of gastric cancer A Luxenburger, N Bougen-Zhukov, MG Fraser, H Beetham, LD Harris, ... Journal of medicinal chemistry 64 (24), 18114-18142, 2021 | 4 | 2021 |
The discovery of 12β-methyl-17-epi-18-nor-bile acids as potent and selective TGR5 agonists A Luxenburger, LD Harris, EM Ure, W Jiao, AD Woolhouse, SA Cameron, ... European Journal of Medicinal Chemistry 250, 115143, 2023 | 3 | 2023 |
C5‐Iminosugar modification of casein kinase 1δ lead 3‐(4‐fluorophenyl)‐5‐isopropyl‐4‐(pyridin‐4‐yl) isoxazole promotes enhanced inhibitor affinity and selectivity T von Drathen, EM Ure, S Kirschner, A Roth, L Meier, AD Woolhouse, ... Archiv der Pharmazie 355 (5), 2100497, 2022 | 3 | 2022 |