PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability A Silva, JA Yunes, BA Cardoso, LR Martins, PY Jotta, M Abecasis, ... The Journal of clinical investigation 118 (11), 3762-3774, 2008 | 503 | 2008 |
Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia PP Zenatti, D Ribeiro, W Li, L Zuurbier, MC Silva, M Paganin, J Tritapoe, ... Nature genetics 43 (10), 932-939, 2011 | 499 | 2011 |
Activation of PI3K is indispensable for interleukin 7–mediated viability, proliferation, glucose use, and growth of T cell acute lymphoblastic leukemia cells JT Barata, A Silva, JG Brandao, LM Nadler, AA Cardoso, VA Boussiotis Journal of Experimental Medicine 200 (5), 659-669, 2004 | 345 | 2004 |
Flip the coin: IL-7 and IL-7R in health and disease JT Barata, SK Durum, B Seddon Nature immunology 20 (12), 1584-1593, 2019 | 326 | 2019 |
Low doses of ionizing radiation promote tumor growth and metastasis by enhancing angiogenesis I Sofia Vala, LR Martins, N Imaizumi, RJ Nunes, J Rino, F Kuonen, ... PloS one 5 (6), e11222, 2010 | 247 | 2010 |
Interleukin-7 promotes survival and cell cycle progression of T-cell acute lymphoblastic leukemia cells by down-regulating the cyclin-dependent kinase inhibitor p27kip1 JT Barata, AA Cardoso, LM Nadler, VA Boussiotis Blood, The Journal of the American Society of Hematology 98 (5), 1524-1531, 2001 | 247 | 2001 |
The MHC class Ib protein ULBP1 is a nonredundant determinant of leukemia/lymphoma susceptibility to γδ T-cell cytotoxicity T Lanca, DV Correia, CF Moita, H Raquel, A Neves-Costa, C Ferreira, ... Blood, The Journal of the American Society of Hematology 115 (12), 2407-2411, 2010 | 204 | 2010 |
IL-7 contributes to the progression of human T-cell acute lymphoblastic leukemias A Silva, ABA Laranjeira, LR Martins, BA Cardoso, J Demengeot, ... Cancer research 71 (14), 4780-4789, 2011 | 164 | 2011 |
IL-7 induces rapid clathrin-mediated internalization and JAK3-dependent degradation of IL-7Rα in T cells CM Henriques, J Rino, RJ Nibbs, GJ Graham, JT Barata Blood, The Journal of the American Society of Hematology 115 (16), 3269-3277, 2010 | 160 | 2010 |
Industry 5.0–past, present, and near future J Barata, I Kayser Procedia Computer Science 219, 778-788, 2023 | 141 | 2023 |
Intracellular reactive oxygen species are essential for PI3K/Akt/mTOR-dependent IL-7-mediated viability of T-cell acute lymphoblastic leukemia cells A Silva, A Girio, I Cebola, CI Santos, F Antunes, JT Barata Leukemia 25 (6), 960-967, 2011 | 134 | 2011 |
Negative prognostic impact of PTEN mutation in pediatric T-cell acute lymphoblastic leukemia PY Jotta, MA Ganazza, A Silva, MB Viana, MJ Da Silva, LJG Zambaldi, ... Leukemia 24 (1), 239-242, 2010 | 113 | 2010 |
AMP-dependent kinase/mammalian target of rapamycin complex 1 signaling in T-cell acute lymphoblastic leukemia: therapeutic implications C Grimaldi, F Chiarini, G Tabellini, F Ricci, PL Tazzari, M Battistelli, ... Leukemia 26 (1), 91-100, 2012 | 112 | 2012 |
IL-7R-mediated signaling in T-cell acute lymphoblastic leukemia: an update ML Oliveira, P Akkapeddi, D Ribeiro, A Melão, JT Barata Advances in biological regulation 71, 88-96, 2019 | 104 | 2019 |
Adult B-cell acute lymphoblastic leukemia cells display decreased PTEN activity and constitutive hyperactivation of PI3K/Akt pathway despite high PTEN protein levels AM Gomes, MVD Soares, P Ribeiro, J Caldas, V Póvoa, LR Martins, ... Haematologica 99 (6), 1062, 2014 | 101 | 2014 |
IL-7 sustains CD31 expression in human naive CD4+ T cells and preferentially expands the CD31+ subset in a PI3K-dependent manner RI Azevedo, MVD Soares, JT Barata, R Tendeiro, A Serra-Caetano, ... Blood, The Journal of the American Society of Hematology 113 (13), 2999-3007, 2009 | 100 | 2009 |
Towards sustainable digital twins for vertical farming J Monteiro, J Barata, M Veloso, L Veloso, J Nunes 2018 Thirteenth International Conference on Digital Information Management …, 2018 | 98 | 2018 |
Apoptotic human neutrophil peptide-1 anti-tumor activity revealed by cellular biomechanics D Gaspar, JM Freire, TR Pacheco, JT Barata, MARB Castanho Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (2), 308-316, 2015 | 96 | 2015 |
The multiple layers of non-genetic regulation of PTEN tumour suppressor activity NC Correia, A Gírio, I Antunes, LR Martins, JT Barata European journal of cancer 50 (1), 216-225, 2014 | 96 | 2014 |
PTEN microdeletions in T-cell acute lymphoblastic leukemia are caused by illegitimate RAG-mediated recombination events RD Mendes, LM Sarmento, K Canté-Barrett, L Zuurbier, ... Blood, The Journal of the American Society of Hematology 124 (4), 567-578, 2014 | 95 | 2014 |