DNMT3A Mutations in Acute Myeloid Leukemia TJ Ley, L Ding, MJ Walter, MD McLellan, T Lamprecht, DE Larson, ... New England Journal of Medicine 363 (25), 2424-2433, 2010 | 2494 | 2010 |
Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens MM Gubin, X Zhang, H Schuster, E Caron, JP Ward, T Noguchi, Y Ivanova, ... Nature 515 (7528), 577-581, 2014 | 2234 | 2014 |
The origin and evolution of mutations in acute myeloid leukemia JS Welch, TJ Ley, DC Link, CA Miller, DE Larson, DC Koboldt, ... Cell 150 (2), 264-278, 2012 | 1908 | 2012 |
Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting H Matsushita, MD Vesely, DC Koboldt, CG Rickert, R Uppaluri, VJ Magrini, ... Nature 482 (7385), 400-404, 2012 | 1482 | 2012 |
A dendritic cell vaccine increases the breadth and diversity of melanoma neoantigen-specific T cells BM Carreno, V Magrini, M Becker-Hapak, S Kaabinejadian, J Hundal, ... Science 348 (6236), 803-808, 2015 | 1466 | 2015 |
Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia TN Wong, G Ramsingh, AL Young, CA Miller, W Touma, JS Welch, ... Nature 518 (7540), 552-555, 2015 | 889 | 2015 |
Quantum circuits with many photons on a programmable nanophotonic chip JM Arrazola, V Bergholm, K Brádler, TR Bromley, MJ Collins, I Dhand, ... Nature 591 (7848), 54-60, 2021 | 599 | 2021 |
Key parameters of tumor epitope immunogenicity revealed through a consortium approach improve neoantigen prediction DK Wells, MM van Buuren, KK Dang, VM Hubbard-Lucey, KCF Sheehan, ... Cell 183 (3), 818-834. e13, 2020 | 426 | 2020 |
pVAC-Seq: A genome-guided in silico approach to identifying tumor neoantigens J Hundal, BM Carreno, AA Petti, GP Linette, OL Griffith, ER Mardis, ... Genome medicine 8, 1-11, 2016 | 418 | 2016 |
Association between mutation clearance after induction therapy and outcomes in acute myeloid leukemia JM Klco, CA Miller, M Griffith, A Petti, DH Spencer, S Ketkar-Kulkarni, ... Jama 314 (8), 811-822, 2015 | 403 | 2015 |
Temporally distinct PD-L1 expression by tumor and host cells contributes to immune escape T Noguchi, JP Ward, MM Gubin, CD Arthur, SH Lee, J Hundal, MJ Selby, ... Cancer immunology research 5 (2), 106-117, 2017 | 305 | 2017 |
pVACtools: a computational toolkit to identify and visualize cancer neoantigens J Hundal, S Kiwala, J McMichael, CA Miller, H Xia, AT Wollam, CJ Liu, ... Cancer immunology research 8 (3), 409-420, 2020 | 194 | 2020 |
Genomic impact of transient low-dose decitabine treatment on primary AML cells JM Klco, DH Spencer, TL Lamprecht, SM Sarkaria, T Wylie, V Magrini, ... Blood, The Journal of the American Society of Hematology 121 (9), 1633-1643, 2013 | 179 | 2013 |
U2AF1 mutations alter sequence specificity of pre-mRNA binding and splicing T Okeyo-Owuor, BS White, R Chatrikhi, DR Mohan, S Kim, M Griffith, ... Leukemia 29 (4), 909-917, 2015 | 153 | 2015 |
The prognostic effects of somatic mutations in ER-positive breast cancer OL Griffith, NC Spies, M Anurag, M Griffith, J Luo, D Tu, B Yeo, J Kunisaki, ... Nature communications 9 (1), 3476, 2018 | 140 | 2018 |
Neoantigen prediction and computational perspectives towards clinical benefit: recommendations from the ESMO Precision Medicine Working Group L De Mattos-Arruda, M Vazquez, F Finotello, R Lepore, E Porta, J Hundal, ... Annals of oncology 31 (8), 978-990, 2020 | 120 | 2020 |
Enforced differentiation of Dnmt3a-null bone marrow leads to failure with c-Kit mutations driving leukemic transformation H Celik, C Mallaney, A Kothari, EL Ostrander, E Eultgen, A Martens, ... Blood, The Journal of the American Society of Hematology 125 (4), 619-628, 2015 | 108 | 2015 |
Neoantigen-targeted CD8+ T cell responses with PD-1 blockade therapy C Puig-Saus, B Sennino, S Peng, CL Wang, Z Pan, B Yuen, B Purandare, ... Nature 615 (7953), 697-704, 2023 | 99 | 2023 |
Standard operating procedure for somatic variant refinement of sequencing data with paired tumor and normal samples EK Barnell, P Ronning, KM Campbell, K Krysiak, BJ Ainscough, LM Sheta, ... Genetics in Medicine 21 (4), 972-981, 2019 | 93 | 2019 |
Genome modeling system: a knowledge management platform for genomics M Griffith, OL Griffith, SM Smith, A Ramu, MB Callaway, AM Brummett, ... PLoS computational biology 11 (7), e1004274, 2015 | 90 | 2015 |