eRNAs promote transcription by establishing chromatin accessibility at defined genomic loci K Mousavi, H Zare, S Dell’Orso, L Grontved, G Gutierrez-Cruz, A Derfoul, ... Molecular cell 51 (5), 606-617, 2013 | 528 | 2013 |
Collagen density regulates the activity of tumor-infiltrating T cells DE Kuczek, AMH Larsen, ML Thorseth, M Carretta, A Kalvisa, ... Journal for immunotherapy of cancer 7, 1-15, 2019 | 363 | 2019 |
Interactome maps of mouse gene regulatory domains reveal basic principles of transcriptional regulation KR Kieffer-Kwon, Z Tang, E Mathe, J Qian, MH Sung, G Li, W Resch, ... Cell 155 (7), 1507-1520, 2013 | 358 | 2013 |
Steroid receptors reprogram FoxA1 occupancy through dynamic chromatin transitions EE Swinstead, TB Miranda, V Paakinaho, S Baek, I Goldstein, M Hawkins, ... Cell 165 (3), 593-605, 2016 | 316 | 2016 |
C/EBP maintains chromatin accessibility in liver and facilitates glucocorticoid receptor recruitment to steroid response elements L Grøntved, S John, S Baek, Y Liu, JR Buckley, C Vinson, G Aguilera, ... The EMBO journal 32 (11), 1568-1583, 2013 | 258 | 2013 |
Reprogramming the chromatin landscape: interplay of the estrogen and glucocorticoid receptors at the genomic level TB Miranda, TC Voss, MH Sung, S Baek, S John, M Hawkins, L Grøntved, ... Cancer research 73 (16), 5130-5139, 2013 | 152 | 2013 |
Live Cell Imaging Unveils Multiple Domain Requirements for In Vivo Dimerization of the Glucocorticoid Receptor DM Presman, MF Ogara, M Stortz, LD Alvarez, JR Pooley, RL Schiltz, ... PLoS biology 12 (3), e1001813, 2014 | 142 | 2014 |
The transcription factor encyclopedia D Yusuf, SL Butland, MI Swanson, E Bolotin, A Ticoll, WA Cheung, ... Genome biology 13, 1-25, 2012 | 141 | 2012 |
Noncanonical thyroid hormone signaling mediates cardiometabolic effects in vivo GS Hönes, H Rakov, J Logan, XH Liao, E Werbenko, AS Pollard, ... Proceedings of the National Academy of Sciences 114 (52), E11323-E11332, 2017 | 128 | 2017 |
Transcriptional activation by the thyroid hormone receptor through ligand-dependent receptor recruitment and chromatin remodelling L Grøntved, JJ Waterfall, DW Kim, S Baek, MH Sung, L Zhao, JW Park, ... Nature communications 6 (1), 7048, 2015 | 128 | 2015 |
The gene encoding the acyl-CoA-binding protein is activated by peroxisome proliferator-activated receptor γ through an intronic response element functionally conserved between … T Helledie, L Grøntved, SS Jensen, P Kiilerich, L Rietveld, T Albrektsen, ... Journal of Biological Chemistry 277 (30), 26821-26830, 2002 | 128 | 2002 |
Tumor-associated macrophages derived from circulating inflammatory monocytes degrade collagen through cellular uptake DH Madsen, HJ Jürgensen, MS Siersbæk, DE Kuczek, LG Cloud, S Liu, ... Cell reports 21 (13), 3662-3671, 2017 | 122 | 2017 |
Collagen density modulates the immunosuppressive functions of macrophages AMH Larsen, DE Kuczek, A Kalvisa, MS Siersbæk, ML Thorseth, ... The Journal of Immunology 205 (5), 1461-1472, 2020 | 102 | 2020 |
Peroxisome proliferator-activated receptor subtype-and cell-type-specific activation of genomic target genes upon adenoviral transgene delivery R Nielsen, L Grøntved, HG Stunnenberg, S Mandrup Molecular and Cellular Biology 26 (15), 5698-5714, 2006 | 98 | 2006 |
High fat diet-induced changes of mouse hepatic transcription and enhancer activity can be reversed by subsequent weight loss M Siersbæk, L Varticovski, S Yang, S Baek, R Nielsen, S Mandrup, ... Scientific Reports 7 (1), 40220, 2017 | 88 | 2017 |
MED14 tethers mediator to the N-terminal domain of peroxisome proliferator-activated receptor γ and is required for full transcriptional activity and adipogenesis L Grøntved, MS Madsen, M Boergesen, RG Roeder, S Mandrup Molecular and cellular biology, 2010 | 83 | 2010 |
C57BL/6J substrain differences in response to high-fat diet intervention MS Siersbæk, N Ditzel, EK Hejbøl, SM Præstholm, LK Markussen, ... Scientific reports 10 (1), 14052, 2020 | 80 | 2020 |
Blockade of beta-adrenergic receptors reduces cancer growth and enhances the response to anti-CTLA4 therapy by modulating the tumor microenvironment KY Fjæstad, AMA Rømer, V Goitea, AZ Johansen, ML Thorseth, ... Oncogene 41 (9), 1364-1375, 2022 | 75 | 2022 |
The adipogenic acetyltransferase Tip60 targets activation function 1 of peroxisome proliferator-activated receptor γ O van Beekum, AB Brenkman, L Grøntved, N Hamers, NJF van den Broek, ... Endocrinology 149 (4), 1840-1849, 2008 | 73 | 2008 |
The PPARγ2 A/B-domain plays a gene-specific role in transactivation and cofactor recruitment A Bugge, L Grøntved, MM Aagaard, R Borup, S Mandrup Molecular endocrinology 23 (6), 794-808, 2009 | 70 | 2009 |