XPB, a subunit of TFIIH, is a target of the natural product triptolide DV Titov, B Gilman, QL He, S Bhat, WK Low, Y Dang, M Smeaton, ... Nature chemical biology 7 (3), 182-188, 2011 | 519 | 2011 |
Characterization of the azinomycin B biosynthetic gene cluster revealing a different iterative type I polyketide synthase for naphthoate biosynthesis Q Zhao, Q He, W Ding, M Tang, Q Kang, Y Yu, W Deng, Q Zhang, J Fang, ... Chemistry & biology 15 (7), 693-705, 2008 | 130 | 2008 |
Highly enantioselective Friedel–Crafts reaction of 4, 7‐dihydroindoles with β, γ‐unsaturated α‐keto esters by chiral Brønsted acids M Zeng, Q Kang, QL He, SL You Advanced Synthesis & Catalysis 350 (14‐15), 2169-2173, 2008 | 124 | 2008 |
Triptolide: reflections on two decades of research and prospects for the future L Tong, Q Zhao, E Datan, GQ Lin, I Minn, MG Pomper, B Yu, D Romo, ... Natural product reports 38 (4), 843-860, 2021 | 113 | 2021 |
Enantioselective synthesis of unsymmetrical triarylmethanes by chiral brønsted acids FL Sun, XJ Zheng, Q Gu, QL He, SL You European Journal of Organic Chemistry 2010 (1), 47-50, 2010 | 113 | 2010 |
Covalent modification of a cysteine residue in the XPB subunit of the general transcription factor TFIIH through single epoxide cleavage of the transcription inhibitor triptolide QL He, DV Titov, J Li, M Tan, Z Ye, Y Zhao, D Romo, JO Liu Angewandte Chemie International Edition 54 (6), 1859-1863, 2015 | 94 | 2015 |
N-Heterocyclic Carbene-Catalyzed Cross-Coupling of Aldehydes with Arylsulfonyl Indoles Y Li, FQ Shi, QL He, SL You Organic Letters 11 (15), 3182-3185, 2009 | 85 | 2009 |
Targeted delivery and sustained antitumor activity of triptolide through glucose conjugation QL He, I Minn, Q Wang, P Xu, SA Head, E Datan, B Yu, MG Pomper, ... Angewandte Chemie 128 (39), 12214-12218, 2016 | 77 | 2016 |
Brønsted Acid Catalyzed Synthesis of Unsymmetrical Arylbis (3-indolyl)-methanes QL He, FL Sun, XJ Zheng, SL You Synlett 2009 (07), 1111-1114, 2009 | 66 | 2009 |
Characterization of Yatakemycin Gene Cluster Revealing a Radical S-Adenosylmethionine Dependent Methyltransferase and Highlighting Spirocyclopropane … W Huang, H Xu, Y Li, F Zhang, XY Chen, QL He, Y Igarashi, GL Tang Journal of the American Chemical Society 134 (21), 8831-8840, 2012 | 59 | 2012 |
Insights into bacterial 6-methylsalicylic acid synthase and its engineering to orsellinic acid synthase for spirotetronate generation W Ding, C Lei, Q He, Q Zhang, Y Bi, W Liu Chemistry & biology 17 (5), 495-503, 2010 | 47 | 2010 |
Self‐resistance to an antitumor antibiotic: a DNA glycosylase triggers the base‐excision repair system in yatakemycin biosynthesis H Xu, W Huang, QL He, ZX Zhao, F Zhang, R Wang, J Kang, GL Tang Angewandte Chemie International Edition 51 (42), 10532-10536, 2012 | 40 | 2012 |
Diazo Reagents with Small Steric Footprints for Simultaneous Arming/SAR Studies of Alcohol-Containing Natural Products via O–H Insertion S Chamni, QL He, Y Dang, S Bhat, JO Liu, D Romo ACS chemical biology 6 (11), 1175-1181, 2011 | 40 | 2011 |
Identification of an old antibiotic clofoctol as a novel activator of unfolded protein response pathways and an inhibitor of prostate cancer M Wang, JS Shim, RJ Li, Y Dang, Q He, M Das, JO Liu British journal of pharmacology 171 (19), 4478-4489, 2014 | 35 | 2014 |
Dissection of Two Acyl‐Transfer Reactions Centered on Acyl‐S‐Carrier Protein Intermediates for Incorporating 5‐Chloro‐6‐methyl‐O‐methylsalicyclic Acid into … QL He, XY Jia, MC Tang, ZH Tian, GL Tang, W Liu ChemBioChem 10 (5), 813-819, 2009 | 33 | 2009 |
Bio-inspired engineering of thiopeptide antibiotics advances the expansion of molecular diversity and utility Z Lin, Q He, W Liu Current Opinion in Biotechnology 48, 210-219, 2017 | 28 | 2017 |
Application of CRISPR in filamentous fungi and macrofungi: from component function to development potentiality JY Shen, Q Zhao, QL He ACS Synthetic Biology 12 (7), 1908-1923, 2023 | 18 | 2023 |
A glucose-triptolide conjugate selectively targets cancer cells under hypoxia E Datan, I Minn, P Xu, QL He, HH Ahn, B Yu, MG Pomper, JO Liu Iscience 23 (9), 2020 | 16 | 2020 |
Unsymmetrically regioselective homodimerization depends on the subcellular colocalization of laccase/fasciclin protein in the biosynthesis of phlegmacins Q Zhao, Z Zhuang, T Liu, Q Yang, QL He, W Liu, GQ Lin ACS Chemical Biology 17 (4), 791-796, 2022 | 13 | 2022 |
Insights into the Functionalization of the Methylsalicyclic Moiety during the Biosynthesis of Chlorothricin by Comparative Kinetic Assays of the Activities of Two KAS III‐like … X Yi, Q Zhao, Z Tian, X Jia, W Cao, W Liu, QL He Chinese Journal of Chemistry 37 (8), 821-826, 2019 | 12 | 2019 |