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G Michael Blackburn
G Michael Blackburn
Professor of Chemical Biology, University of Sheffield
Zweryfikowany adres z sheffield.ac.uk - Strona główna
Tytuł
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Cytowane przez
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Nucleic acids in chemistry and biology
GM Blackburn
Royal Society of Chemistry, 2006
13632006
The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design
RJ Russell, LF Haire, DJ Stevens, PJ Collins, YP Lin, GM Blackburn, ...
Nature 443 (7107), 45-49, 2006
10142006
Clodronate and liposome‐encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5′‐(β, γ‐dichloromethylene) triphosphate, by mammalian cells in vitro
JC Frith, J Mönkkönen, GM Blackburn, RGG Russell, MJ Rogers
Journal of Bone and Mineral Research 12 (9), 1358-1367, 1997
6301997
Structure and catalytic mechanism of the human histone methyltransferase SET7/9
B Xiao, C Jing, JR Wilson, PA Walker, N Vasisht, G Kelly, S Howell, ...
Nature 421 (6923), 652-656, 2003
4862003
Uracil-DNA glycosylase–DNA substrate and product structures: Conformational strain promotes catalytic efficiency by coupled stereoelectronic effects
SS Parikh, G Walcher, GD Jones, G Slupphaug, HE Krokan, ...
Proceedings of the National Academy of Sciences 97 (10), 5083-5088, 2000
3252000
Crystal structure and functional analysis of the histone methyltransferase SET7/9
JR Wilson, C Jing, PA Walker, SR Martin, SA Howell, GM Blackburn, ...
Cell 111 (1), 105-115, 2002
2932002
Uracil-DNA glycosylase acts by substrate autocatalysis
AR Dinner, GM Blackburn, M Karplus
Nature 413 (6857), 752-755, 2001
2712001
The synthesis and metal binding characteristics of novel, isopolar phosphonate analogues of nucleotides
GM Blackburn, DE Kent, F Kolkmann
Journal of the Chemical Society, Perkin Transactions 1, 1119-1125, 1984
2701984
Why did Nature select phosphate for its dominant roles in biology?
MW Bowler, MJ Cliff, JP Waltho, GM Blackburn
New Journal of Chemistry 34 (5), 784-794, 2010
2072010
Phosphonates as analogues of biological phosphates
GM Blackburn
1981981
The mechanism of the aminolysis of methyl formate
GM Blackburn, WP Jencks
Journal of the American Chemical Society 90 (10), 2638-2645, 1968
1861968
Genetic, biochemical, and crystallographic characterization of Fhit–substrate complexes as the active signaling form of Fhit
HC Pace, PN Garrison, AK Robinson, LD Barnes, A Draganescu, ...
Proceedings of the National Academy of Sciences 95 (10), 5484-5489, 1998
1841998
Monofluoro-and difluoro-methylenebisphosphonic acids: isopolar analogues of pyrophosphoric acid
GM Blackburn, DA England, F Kolkmann
Journal of the Chemical Society, Chemical Communications, 930-932, 1981
1801981
Antibiotic recognition by binuclear metallo-β-lactamases revealed by X-ray crystallography
J Spencer, J Read, RB Sessions, S Howell, GM Blackburn, SJ Gamblin
Journal of the American Chemical Society 127 (41), 14439-14444, 2005
1562005
Toward antibody-directed" abzyme" prodrug therapy, ADAPT: carbamate prodrug activation by a catalytic antibody and its in vitro application to human tumor cell killing.
P Wentworth, A Datta, D Blakey, T Boyle, LJ Partridge, GM Blackburn
Proceedings of the National Academy of Sciences 93 (2), 799-803, 1996
1561996
Bisphosphonates are incorporated into adenine nucleotides by human aminoacyl-tRNA synthetase enzymes
MJ Rogers, RJ Brown, V Hodkin, GM Blackburn, RGG Russell, DJ Watts
Biochemical and biophysical research communications 224 (3), 863-869, 1996
1521996
Synthesis of α-and γ-fluoroalkylphosphonates
GM Blackburn, DE Kent
Journal of the Chemical Society, Perkin Transactions 1, 913-917, 1986
1421986
Incorporation of bisphosphonates into adenine nucleotides by amoebae of the cellular slime mould Dictyostelium discoideum
MJ Rogers, X Ji, RGG Russell, GM Blackburn, MP Williamson, AV Bayless, ...
Biochemical Journal 303 (1), 303-311, 1994
1361994
Derivatives of tamoxifen. Dependence of antiestrogenicity on the 4-substituent
R McCague, G Leclercq, N Legros, J Goodman, GM Blackburn, M Jarman, ...
Journal of medicinal chemistry 32 (12), 2527-2533, 1989
1211989
Isopolar vs isosteric phosphonate analogues of nucleotides
GM Blackburn, F Eckstein, DE Kent, TD Perrée
Nucleosides, Nucleotides & Nucleic Acids 4 (1-2), 165-167, 1985
1121985
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