Manfred Jung

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Wolfgang SipplProfessor of Medicinal ChemistryZweryfikowany adres z pharmazie.uni-halle.de
Martin MarekResearch Scientist & Team Leader, Loschmidt Laboratories, Masaryk UniversityZweryfikowany adres z recetox.muni.cz
Eric VerdinCEO & President, Buck Institute for Research on AgingZweryfikowany adres z buckinstitute.org
Attila LehotzkyInstitute of Enzymology, HUN-RESZweryfikowany adres z ttk.hu
Guilherme OliveiraInstituto Tecnológico ValeZweryfikowany adres z itv.org
Lucia Altucci, MD, PhDSeconda Università di NapoliZweryfikowany adres z unina2.it
Stefan GüntherProfessor for Pharmaceutical Bioinformatics, Freiburg UniversityZweryfikowany adres z pharmazie.uni-freiburg.de
David ChristiansonProfessor of Chemistry, University of PennsylvaniaZweryfikowany adres z sas.upenn.edu
Antonello MaiProfessore di Chimica Farmaceutica, Sapienza Università di RomaZweryfikowany adres z uniroma1.it
Bernhard BreitAlbert-Ludwigs-Universität FreiburgZweryfikowany adres z chemie.uni-freiburg.de
Brian J. NorthCreighton University School of MedicineZweryfikowany adres z creighton.edu
Clarissa GerhauserGroup Leader, German Cancer Research Center (dkfz.) HeidelbergZweryfikowany adres z dkfz.de
Melanie OttZweryfikowany adres z gladstone.ucsf.edu
Dante Rotili, PhDFull Professor of Medicinal Chemistry, Department of Science,"Roma Tre" University of RomeZweryfikowany adres z uniroma3.it
Xavier LucasComputational medicinal chemist at Monte Rosa Therapeutics, BaselZweryfikowany adres z monterosatx.com
Matthias KassackProfessorZweryfikowany adres z uni-duesseldorf.de
Martin PippelBioinformatician, NBIS - National Bioinformatics Infrastructure SwedenZweryfikowany adres z nbis.se
Suhaib ShekfehMartin-Luther-University Medicinal ChemistryZweryfikowany adres z pharmazie.uni-hale.de
David A. SinclairHarvard Medical School (Genetics)Zweryfikowany adres z hms.harvard.edu
Huanbiao MoProfessor of Nutrition, Georgia State UniversityZweryfikowany adres z gsu.edu

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Manfred Jung

Institute of Pharmaceutical Sciences, University of Freiburg; former University of Münster, Ottawa

Zweryfikowany adres z pharmazie.uni-freiburg.de - Strona główna

Medicinal Chemistry Chemical Biology: Chemical Epigenetics Histone acetyltransferases deacetylases methyltransferases


Tytuł Sortuj wg cytatów Sortuj wg roku Sortuj wg tytułu	Cytowane przez Cytowane przez	Rok
Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy K Keller, M Jung Epigenetic Therapy of Cancer: Preclinical Models and Treatment Approaches …, 2013	472	2013
Targeting histone methyltransferases and demethylases in clinical trials for cancer therapy L Morera, M Lübbert, M Jung Clinical epigenetics 8, 1-16, 2016	440	2016
SIRT1 regulates HIV transcription via Tat deacetylation S Pagans, A Pedal, BJ North, K Kaehlcke, BL Marshall, A Dorr, ... PLoS biology 3 (2), e41, 2005	433	2005
Chemically induced degradation of sirtuin 2 (Sirt2) by a proteolysis targeting chimera (PROTAC) based on sirtuin rearranging ligands (SirReals) M Schiedel, D Herp, S Hammelmann, S Swyter, A Lehotzky, D Robaa, ... Journal of medicinal chemistry 61 (2), 482-491, 2018	314	2018
HDAC8: a multifaceted target for therapeutic interventions A Chakrabarti, I Oehme, O Witt, G Oliveira, W Sippl, C Romier, RJ Pierce, ... Trends in pharmacological sciences 36 (7), 481-492, 2015	301	2015
Selective Sirt2 inhibition by ligand-induced rearrangement of the active site T Rumpf, M Schiedel, B Karaman, C Roessler, BJ North, A Lehotzky, ... Nature communications 6 (1), 6263, 2015	298	2015
Inhibitors of histone deacetylase as new anticancer agents M Jung Current Medicinal Chemistry 8 (12), 1505-1511, 2001	288	2001
Amide analogues of trichostatin A as inhibitors of histone deacetylase and inducers of terminal cell differentiation M Jung, G Brosch, D Kölle, H Scherf, C Gerhäuser, P Loidl Journal of Medicinal Chemistry 42 (22), 4669-4679, 1999	272	1999
Structure–Activity Studies on Suramin Analogues as Inhibitors of NAD⁺‐Dependent Histone Deacetylases (Sirtuins) J Trapp, R Meier, D Hongwiset, MU Kassack, W Sippl, M Jung ChemMedChem: Chemistry Enabling Drug Discovery 2 (10), 1419-1431, 2007	245	2007
The emerging therapeutic potential of histone methyltransferase and demethylase inhibitors A Spannhoff, AT Hauser, R Heinke, W Sippl, M Jung ChemMedChem: Chemistry Enabling Drug Discovery 4 (10), 1568-1582, 2009	207	2009
Structure–activity studies on splitomicin derivatives as sirtuin inhibitors and computational prediction of binding mode RC Neugebauer, U Uchiechowska, R Meier, H Hruby, V Valkov, E Verdin, ... Journal of medicinal chemistry 51 (5), 1203-1213, 2008	207	2008
Structural Basis for the Inhibition of Histone Deacetylase 8 (HDAC8), a Key Epigenetic Player in the Blood Fluke Schistosoma mansoni M Marek, S Kannan, AT Hauser, M Moraes Mourão, S Caby, V Cura, ... PLoS pathogens 9 (9), e1003645, 2013	206	2013
Adenosine mimetics as inhibitors of NAD+-dependent histone deacetylases, from kinase to sirtuin inhibition J Trapp, A Jochum, R Meier, L Saunders, B Marshall, C Kunick, E Verdin, ... Journal of medicinal chemistry 49 (25), 7307-7316, 2006	206	2006
Target-based approach to inhibitors of histone arginine methyltransferases A Spannhoff, R Heinke, I Bauer, P Trojer, E Metzger, R Gust, R Schüle, ... Journal of medicinal chemistry 50 (10), 2319-2325, 2007	176	2007
Enhancement of radiation sensitivity of human squamous carcinoma cells by histone deacetylase inhibitors Y Zhang, M Jung, A Dritschilo, M Jung Radiation research 161 (6), 667-674, 2004	176	2004
Inhibitors of human histone deacetylase: synthesis and enzyme and cellular activity of straight chain hydroxamates SW Remiszewski, LC Sambucetti, P Atadja, KW Bair, WD Cornell, ... Journal of medicinal chemistry 45 (4), 753-757, 2002	170	2002
Subtype selective substrates for histone deacetylases B Heltweg, F Dequiedt, BL Marshall, C Brauch, M Yoshida, N Nishino, ... Journal of medicinal chemistry 47 (21), 5235-5243, 2004	162	2004
Impairment of prostate cancer cell growth by a selective and reversible LSD1 inhibitor D Willmann, S Lim, S Wetzel, E Metzger, A Jandausch, W Wilk, M Jung, ... International Journal of Cancer 128, 574-586, 2012	157*	2012
In vitro assays for the determination of histone deacetylase activity B Heltweg, J Trapp, M Jung Methods 36 (4), 332-337, 2005	156	2005
Histone acetyltransferase inhibitors block neuroblastoma cell growth in vivo JM Gajer, SD Furdas, A Gründer, M Gothwal, U Heinicke, K Keller, ... Oncogenesis 4 (2), e137-e137, 2015	152	2015

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