Increased ketone body oxidation provides additional energy for the failing heart without improving cardiac efficiency KL Ho, L Zhang, C Wagg, R Al Batran, K Gopal, J Levasseur, T Leone, ... Cardiovascular research 115 (11), 1606-1616, 2019 | 181 | 2019 |
Impaired branched chain amino acid oxidation contributes to cardiac insulin resistance in heart failure GM Uddin, L Zhang, S Shah, A Fukushima, CS Wagg, K Gopal, ... Cardiovascular diabetology 18, 1-12, 2019 | 156 | 2019 |
Targeting ceramide metabolism in obesity H Aburasayn, R Al Batran, JR Ussher American Journal of Physiology-Endocrinology And Metabolism 311 (2), E423-E435, 2016 | 121 | 2016 |
Chronically elevating circulating ketones can reduce cardiac inflammation and blunt the development of heart failure NJ Byrne, S Soni, S Takahara, M Ferdaoussi, R Al Batran, AM Darwesh, ... Circulation: Heart Failure 13 (6), e006573, 2020 | 89 | 2020 |
Glucagon-like peptide-1 receptor action in the vasculature M Almutairi, R Al Batran, JR Ussher Peptides 111, 26-32, 2019 | 76 | 2019 |
FoxO1 regulates myocardial glucose oxidation rates via transcriptional control of pyruvate dehydrogenase kinase 4 expression K Gopal, B Saleme, R Al Batran, H Aburasayn, A Eshreif, KL Ho, WK Ma, ... American Journal of Physiology-Heart and Circulatory Physiology 313 (3 …, 2017 | 66 | 2017 |
The GLP-1 receptor agonist liraglutide increases myocardial glucose oxidation rates via indirect mechanisms and mitigates experimental diabetic cardiomyopathy M Almutairi, K Gopal, AA Greenwell, A Young, R Gill, H Aburasayn, ... Canadian Journal of Cardiology 37 (1), 140-150, 2021 | 64 | 2021 |
Pimozide alleviates hyperglycemia in diet-induced obesity by inhibiting skeletal muscle ketone oxidation R Al Batran, K Gopal, ME Capozzi, JJ Chahade, B Saleme, ... Cell Metabolism 31 (5), 909-919. e8, 2020 | 57 | 2020 |
FoxO1 inhibition alleviates type 2 diabetes-related diastolic dysfunction by increasing myocardial pyruvate dehydrogenase activity K Gopal, R Al Batran, TR Altamimi, AA Greenwell, CT Saed, SAT Dakhili, ... Cell Reports 35 (1), 2021 | 53 | 2021 |
Cardiac-specific Deletion of Pyruvate Dehydrogenase impairs glucose Oxidation rates and induces Diastolic Dysfunction K Gopal, M Almutairi, R Al Batran, F Eaton, M Gandhi, JR Ussher Frontiers in cardiovascular medicine 5, 17, 2018 | 45 | 2018 |
Cytosolic carnitine acetyltransferase as a source of cytosolic acetyl-CoA: a possible mechanism for regulation of cardiac energy metabolism TR Altamimi, PD Thomas, AM Darwesh, N Fillmore, MU Mahmoud, ... Biochemical Journal 475 (5), 959-976, 2018 | 39 | 2018 |
Glucagon-like peptide-1 receptor mediated control of cardiac energy metabolism R Al Batran, M Almutairi, JR Ussher Peptides 100, 94-100, 2018 | 30 | 2018 |
l‐Citrulline supplementation improves glucose and exercise tolerance in obese male mice A Eshreif, R Al Batran, KL Jamieson, AM Darwesh, K Gopal, ... Experimental Physiology 105 (2), 270-281, 2020 | 21 | 2020 |
The antianginal ranolazine mitigates obesity-induced nonalcoholic fatty liver disease and increases hepatic pyruvate dehydrogenase activity R Al Batran, K Gopal, H Aburasayn, A Eshreif, M Almutairi, AA Greenwell, ... JCI insight 4 (1), 2019 | 20 | 2019 |
Dietary-induced obesity, hepatic cytochrome P450, and lidocaine metabolism: comparative effects of high-fat diets in mice and rats and reversibility of effects with … HM Al Nebaihi, R Al Batran, JR Ussher, ZH Maayah, AOS El-Kadi, ... Journal of Pharmaceutical Sciences 109 (2), 1199-1210, 2020 | 17 | 2020 |
Role of cytochrome p450 and soluble epoxide hydrolase enzymes and their associated metabolites in the pathogenesis of diabetic cardiomyopathy ZH Maayah, E McGinn, R Al Batran, K Gopal, JR Ussher, AOS El-Kadi Journal of Cardiovascular Pharmacology 74 (3), 235-245, 2019 | 14 | 2019 |
Barth syndrome-related cardiomyopathy is associated with a reduction in myocardial glucose oxidation AA Greenwell, K Gopal, TR Altamimi, CT Saed, F Wang, ... American Journal of Physiology-Heart and Circulatory Physiology 320 (6 …, 2021 | 13 | 2021 |
The antipsychotic dopamine 2 receptor antagonist diphenylbutylpiperidines improve glycemia in experimental obesity by inhibiting succinyl-CoA: 3-ketoacid CoA transferase SA Tabatabaei Dakhili, AA Greenwell, K Yang, R Abou Farraj, CT Saed, ... Diabetes 72 (1), 126-134, 2023 | 11 | 2023 |
An isoproteic cocoa butter-based ketogenic diet fails to improve glucose homeostasis and promote weight loss in obese mice AA Greenwell, CT Saed, SAT Dakhili, KL Ho, K Gopal, JSF Chan, ... American Journal of Physiology-Endocrinology and Metabolism, 2022 | 10 | 2022 |
Skeletal muscle-specific Cre recombinase expression, controlled by the human α-skeletal actin promoter, improves glucose tolerance in mice fed a high-fat diet R Al Batran, K Gopal, MD Martin, KL Ho, M Almutairi, H Aburasayn, ... Diabetologia 61, 1849-1855, 2018 | 10 | 2018 |