Investigation of the effect of hepatic metabolism on off-target cardiotoxicity in a multi-organ human-on-a-chip system C Oleaga, A Riu, S Rothemund, A Lavado, CW McAleer, CJ Long, ... Biomaterials 182, 176-190, 2018 | 159 | 2018 |
Multi-organ system for the evaluation of efficacy and off-target toxicity of anticancer therapeutics CW McAleer, CJ Long, D Elbrecht, T Sasserath, LR Bridges, JW Rumsey, ... Science translational medicine 11 (497), eaav1386, 2019 | 150 | 2019 |
Stem cell derived phenotypic human neuromuscular junction model for dose response evaluation of therapeutics N Santhanam, L Kumanchik, X Guo, F Sommerhage, Y Cai, M Jackson, ... Biomaterials 166, 64-78, 2018 | 117 | 2018 |
On the potential of in vitro organ-chip models to define temporal pharmacokinetic-pharmacodynamic relationships CW McAleer, A Pointon, CJ Long, RL Brighton, BD Wilkin, LR Bridges, ... Scientific reports 9 (1), 9619, 2019 | 95 | 2019 |
Differential monocyte actuation in a three‐organ functional innate immune system‐on‐a‐chip T Sasserath, JW Rumsey, CW McAleer, LR Bridges, CJ Long, D Elbrecht, ... Advanced science 7 (13), 2000323, 2020 | 77 | 2020 |
Microphysiological heart–liver body-on-a-chip system with a skin mimic for evaluating topical drug delivery CPP de Mello, C Carmona-Moran, CW McAleer, J Perez, EA Coln, ... Lab on a Chip 20 (4), 749-759, 2020 | 73 | 2020 |
Self-contained, low-cost Body-on-a-Chip systems for drug development YI Wang, C Oleaga, CJ Long, MB Esch, CW McAleer, PG Miller, ... Experimental biology and medicine 242 (17), 1701-1713, 2017 | 71 | 2017 |
A phenotypic in vitro model for the main determinants of human whole heart function M Stancescu, P Molnar, CW McAleer, W McLamb, CJ Long, C Oleaga, ... Biomaterials 60, 20-30, 2015 | 69 | 2015 |
Validation of an adipose-liver human-on-a-chip model of NAFLD for preclinical therapeutic efficacy evaluation VL Slaughter, JW Rumsey, R Boone, D Malik, Y Cai, NN Sriram, CJ Long, ... Scientific Reports 11 (1), 13159, 2021 | 50 | 2021 |
A multiplexed chip-based assay system for investigating the functional development of human skeletal myotubes in vitro AST Smith, CJ Long, K Pirozzi, S Najjar, C McAleer, HH Vandenburgh, ... Journal of biotechnology 185, 15-18, 2014 | 41 | 2014 |
Classical complement pathway inhibition in a “Human‐On‐A‐Chip” model of autoimmune demyelinating neuropathies JW Rumsey, C Lorance, M Jackson, T Sasserath, CW McAleer, CJ Long, ... Advanced therapeutics 5 (6), 2200030, 2022 | 40 | 2022 |
A human‐based functional NMJ system for personalized ALS modeling and drug testing X Guo, V Smith, M Jackson, M Tran, M Thomas, A Patel, E Lorusso, ... Advanced therapeutics 3 (11), 2000133, 2020 | 39 | 2020 |
Functional skeletal muscle model derived from SOD1-mutant ALS patient iPSCs recapitulates hallmarks of disease progression A Badu-Mensah, X Guo, CW McAleer, JW Rumsey, JJ Hickman Scientific reports 10 (1), 14302, 2020 | 37 | 2020 |
Correlation of embryonic skeletal muscle myotube physical characteristics with contractile force generation on an atomic force microscope-based bio-microelectromechanical … KL Pirozzi, CJ Long, CW McAleer, AST Smith, JJ Hickman Applied physics letters 103 (8), 2013 | 37 | 2013 |
Microphysiological systems and low-cost microfluidic platform with analytics AST Smith, CJ Long, BJ Berry, C McAleer, M Stancescu, P Molnar, ... Stem cell research & therapy 4, 1-5, 2013 | 35 | 2013 |
Characterization of functional human skeletal myotubes and neuromuscular junction derived—from the same induced pluripotent stem cell source X Guo, A Badu-Mensah, MC Thomas, CW McAleer, JJ Hickman Bioengineering 7 (4), 133, 2020 | 29 | 2020 |
Mechanistic investigation of adult myotube response to exercise and drug treatment in vitro using a multiplexed functional assay system CW McAleer, AST Smith, S Najjar, K Pirozzi, CJ Long, JJ Hickman Journal of Applied Physiology 117 (11), 1398-1405, 2014 | 27 | 2014 |
Utilization of microscale silicon cantilevers to assess cellular contractile function in vitro AST Smith, CJ Long, C McAleer, N Bobbitt, B Srinivasan, JJ Hickman Journal of visualized experiments: JoVE, 51866, 2014 | 22 | 2014 |
Functional myotube formation from adult rat satellite cells in a defined serum‐free system CW McAleer, JW Rumsey, M Stancescu, JJ Hickman Biotechnology progress 31 (4), 997-1003, 2015 | 21 | 2015 |
Nanoclay suspension-enabled extrusion bioprinting of three-dimensional soft structures Y Jin, R Xiong, PJ Antonelli, CJ Long, CW McAleer, JJ Hickman, Y Huang Journal of Manufacturing Science and Engineering 143 (12), 121004, 2021 | 17 | 2021 |