Global genetic analysis in mice unveils central role for cilia in congenital heart disease Y Li, NT Klena, GC Gabriel, X Liu, AJ Kim, K Lemke, Y Chen, B Chatterjee, ... Nature 521 (7553), 520-524, 2015 | 442 | 2015 |
DYX1C1 is required for axonemal dynein assembly and ciliary motility A Tarkar, NT Loges, CE Slagle, R Francis, GW Dougherty, JV Tamayo, ... Nature genetics 45 (9), 995-1003, 2013 | 331 | 2013 |
IFT27 links the BBSome to IFT for maintenance of the ciliary signaling compartment T Eguether, JT San Agustin, BT Keady, JA Jonassen, Y Liang, R Francis, ... Developmental cell 31 (3), 279-290, 2014 | 294 | 2014 |
Connexin43 associated with an N-cadherin-containing multiprotein complex is required for gap junction formation in NIH3T3 cells CJ Wei, R Francis, X Xu, CW Lo Journal of Biological Chemistry 280 (20), 19925-19936, 2005 | 262 | 2005 |
High prevalence of respiratory ciliary dysfunction in congenital heart disease patients with heterotaxy N Nakhleh, R Francis, RA Giese, X Tian, Y Li, MA Zariwala, H Yagi, ... Circulation 125 (18), 2232-2242, 2012 | 203 | 2012 |
Connexin 43-mediated modulation of polarized cell movement and the directional migration of cardiac neural crest cells X Xu, R Francis, CJ Wei, KL Linask, CW Lo Oxford University Press for The Company of Biologists Limited 133 (18), 3629 …, 2006 | 198 | 2006 |
Refining rodent husbandry: the mouse: report of the Rodent Refinement Working Party M Jennings, GR Batchelor, PF Brain, A Dick, H Elliott, RJ Francis, ... Laboratory animals 32 (3), 233-259, 1998 | 179 | 1998 |
Discovery of four recessive developmental disorders using probabilistic genotype and phenotype matching among 4,125 families Nature Genetics 47 (11), 1363-9, 2015 | 178 | 2015 |
ARMC4 mutations cause primary ciliary dyskinesia with randomization of left/right body asymmetry R Hjeij, A Lindstrand, R Francis, MA Zariwala, X Liu, Y Li, R Damerla, ... The American Journal of Human Genetics 93 (2), 357-367, 2013 | 177 | 2013 |
Connexin43 modulates cell polarity and directional cell migration by regulating microtubule dynamics R Francis, X Xu, H Park, CJ Wei, S Chang, B Chatterjee, C Lo PloS one 6 (10), e26379, 2011 | 137 | 2011 |
DNAH6 and Its Interactions with PCD Genes in Heterotaxy and Primary Ciliary Dyskinesia Y Li, H Yagi, EO Onuoha, RR Damerla, R Francis, Y Furutani, M Tariq, ... PLoS genetics 12 (2), e1005821, 2016 | 126 | 2016 |
Heterotaxy and complex structural heart defects in a mutant mouse model of primary ciliary dyskinesia SY Tan, J Rosenthal, XQ Zhao, RJ Francis, B Chatterjee, SL Sabol, ... The Journal of clinical investigation 117 (12), 3742-3752, 2007 | 126 | 2007 |
Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton C Cui, B Chatterjee, TP Lozito, Z Zhang, RJ Francis, H Yagi, LM Swanhart, ... PLoS biology 11 (11), e1001720, 2013 | 122 | 2013 |
Connexin 43 regulates epicardial cell polarity and migration in coronary vascular development DY Rhee, XQ Zhao, RJB Francis, GY Huang, JD Mably, CW Lo Development 136 (18), 3185-3193, 2009 | 107 | 2009 |
Disruption of Mks1 localization to the mother centriole causes cilia defects and developmental malformations in Meckel-Gruber syndrome C Cui, B Chatterjee, D Francis, Q Yu, JT SanAgustin, R Francis, T Tansey, ... Disease models & mechanisms 4 (1), 43-56, 2011 | 102 | 2011 |
Massively parallel sequencing identifies the gene Megf8 with ENU-induced mutation causing heterotaxy Z Zhang, D Alpert, R Francis, B Chatterjee, Q Yu, T Tansey, SL Sabol, ... Proceedings of the National Academy of Sciences 106 (9), 3219-3224, 2009 | 82 | 2009 |
Refinement and reduction in production of genetically modified mice V Robinson, DB Morton, D Anderson, JFA Carver Laboratory Animals 37, 1, 2003 | 78 | 2003 |
Increased postoperative respiratory complications in heterotaxy congenital heart disease patients with respiratory ciliary dysfunction B Harden, X Tian, R Giese, N Nakhleh, S Kureshi, R Francis, ... The Journal of thoracic and cardiovascular surgery 147 (4), 1291-1298. e2, 2014 | 70 | 2014 |
Bves directly interacts with GEFT, and controls cell shape and movement through regulation of Rac1/Cdc42 activity TK Smith, HA Hager, R Francis, DM Kilkenny, CW Lo, DM Bader Proceedings of the National Academy of Sciences 105 (24), 8298-8303, 2008 | 69 | 2008 |
Congenital heart disease and the specification of left-right asymmetry RJB Francis, A Christopher, WA Devine, L Ostrowski, C Lo American Journal of Physiology-Heart and Circulatory Physiology 302 (10 …, 2012 | 68 | 2012 |