Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer’s disease B Zhang, C Gaiteri, LG Bodea, Z Wang, J McElwee, AA Podtelezhnikov, ... Cell 153 (3), 707-720, 2013 | 1838 | 2013 |
Dissecting self-renewal in stem cells with RNA interference N Ivanova, R Dobrin, R Lu, I Kotenko, J Levorse, C DeCoste, X Schafer, ... Nature 442 (7102), 533-538, 2006 | 1273 | 2006 |
The topological relationship between the large-scale attributes and local interaction patterns of complex networks A Vazquez, R Dobrin, D Sergi, JP Eckmann, ZN Oltvai, AL Barabási Proceedings of the National Academy of Sciences 101 (52), 17940-17945, 2004 | 385 | 2004 |
Aggregation of topological motifs in the Escherichia coli transcriptional regulatory network R Dobrin, QK Beg, AL Barabási, ZN Oltvai BMC bioinformatics 5, 1-8, 2004 | 297 | 2004 |
A functional genomics predictive network model identifies regulators of inflammatory bowel disease LA Peters, J Perrigoue, A Mortha, A Iuga, W Song, EM Neiman, ... Nature genetics 49 (10), 1437-1449, 2017 | 271 | 2017 |
NDEx, the network data exchange D Pratt, J Chen, D Welker, R Rivas, R Pillich, V Rynkov, K Ono, C Miello, ... Cell systems 1 (4), 302-305, 2015 | 265 | 2015 |
A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma A Sharma, J Menche, CC Huang, T Ort, X Zhou, M Kitsak, N Sahni, ... Human molecular genetics 24 (11), 3005-3020, 2015 | 219 | 2015 |
A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort DM Greenawalt, R Dobrin, E Chudin, IJ Hatoum, C Suver, J Beaulaurier, ... Genome research 21 (7), 1008-1016, 2011 | 216 | 2011 |
Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes H Zhong, J Beaulaurier, PY Lum, C Molony, X Yang, DJ MacNeil, ... PLoS genetics 6 (5), e1000932, 2010 | 206 | 2010 |
STK11 and KEAP1 mutations as prognostic biomarkers in an observational real-world lung adenocarcinoma cohort S Papillon-Cavanagh, P Doshi, R Dobrin, J Szustakowski, AM Walsh ESMO open 5 (2), e000706, 2020 | 197 | 2020 |
Multi-tissue coexpression networks reveal unexpected subnetworks associated with disease R Dobrin, J Zhu, C Molony, C Argman, ML Parrish, S Carlson, MF Allan, ... Genome biology 10, 1-13, 2009 | 182 | 2009 |
Common body mass index-associated variants confer risk of extreme obesity C Cotsapas, EK Speliotes, IJ Hatoum, DM Greenawalt, R Dobrin, PY Lum, ... Human molecular genetics 18 (18), 3502-3507, 2009 | 154 | 2009 |
The arrestin domain-containing 3 protein regulates body mass and energy expenditure P Patwari, V Emilsson, EE Schadt, WA Chutkow, S Lee, A Marsili, ... Cell metabolism 14 (5), 671-683, 2011 | 138 | 2011 |
Variants in TRIM22 that affect NOD2 signaling are associated with very-early-onset inflammatory bowel disease Q Li, CH Lee, LA Peters, LA Mastropaolo, C Thoeni, A Elkadri, T Schwerd, ... Gastroenterology 150 (5), 1196-1207, 2016 | 113 | 2016 |
Pparγ2 is a key driver of longevity in the mouse C Argmann, R Dobrin, S Heikkinen, A Auburtin, L Pouilly, TA Cock, ... PLoS genetics 5 (12), e1000752, 2009 | 98 | 2009 |
Integrative genomic deconvolution of rheumatoid arthritis GWAS loci into gene and cell type associations AM Walsh, JW Whitaker, CC Huang, Y Cherkas, SL Lamberth, ... Genome biology 17, 1-16, 2016 | 83 | 2016 |
Integrating personalized gene expression profiles into predictive disease-associated gene pools J Menche, E Guney, A Sharma, PJ Branigan, MJ Loza, F Baribaud, ... NPJ systems biology and applications 3 (1), 10, 2017 | 67 | 2017 |
Synthesis of 53 tissue and cell line expression QTL datasets reveals master eQTLs X Zhang, HJ Gierman, D Levy, A Plump, R Dobrin, HHH Goring, ... BMC genomics 15, 1-19, 2014 | 63 | 2014 |
Inverse regulation of inflammation and mitochondrial function in adipose tissue defines extreme insulin sensitivity in morbidly obese patients M Qatanani, Y Tan, R Dobrin, DM Greenawalt, G Hu, W Zhao, JM Olefsky, ... Diabetes 62 (3), 855-863, 2013 | 54 | 2013 |
High-throughput characterization of blood serum proteomics of IBD patients with respect to aging and genetic factors AF Di Narzo, SE Telesco, C Brodmerkel, C Argmann, LA Peters, K Li, ... PLoS genetics 13 (1), e1006565, 2017 | 52 | 2017 |