Targeting mitochondrial oxidative phosphorylation eradicates therapy-resistant chronic myeloid leukemia stem cells EM Kuntz, P Baquero, AM Michie, K Dunn, S Tardito, TL Holyoake, ... Nature medicine 23 (10), 1234-1240, 2017 | 511 | 2017 |
Regulation of thymocyte differentiation: pre-TCR signals and β-selection AM Michie, JC Zúñiga-Pflücker Seminars in immunology 14 (5), 311-323, 2002 | 338 | 2002 |
Obligatory role for cooperative signaling by pre-TCR and Notch during thymocyte differentiation M Ciofani, TM Schmitt, A Ciofani, AM Michie, N Cuburu, A Aublin, ... The Journal of Immunology 172 (9), 5230-5239, 2004 | 329 | 2004 |
Identification of a novel developmental stage marking lineage commitment of progenitor thymocytes JR Carlyle, AM Michie, C Furlonger, T Nakano, MJ Lenardo, CJ Paige, ... The Journal of experimental medicine 186 (2), 173-182, 1997 | 183 | 1997 |
Duration and strength of extracellular signal-regulated kinase signals are altered during positive versus negative thymocyte selection S Mariathasan, A Zakarian, D Bouchard, AM Michie, JC Zúñiga-Pflücker, ... The Journal of Immunology 167 (9), 4966-4973, 2001 | 159 | 2001 |
Branching out to gain control: how the pre-TCR is linked to multiple functions AM Kruisbeek, MC Haks, M Carleton, DL Wiest, AM Michie, ... Immunology today 21 (12), 637-644, 2000 | 153 | 2000 |
Death‐associated protein kinase (DAPK) and signal transduction: regulation in cancer AM Michie, AM McCaig, R Nakagawa, M Vukovic The FEBS journal 277 (1), 74-80, 2010 | 149 | 2010 |
Clonal characterization of a bipotent T cell and NK cell progenitor in the mouse fetal thymus AM Michie, JR Carlyle, TM Schmitt, B Ljutic, SK Cho, Q Fong, ... The Journal of Immunology 164 (4), 1730-1733, 2000 | 143 | 2000 |
Targeting quiescent leukemic stem cells using second generation autophagy inhibitors P Baquero, A Dawson, A Mukhopadhyay, EM Kuntz, R Mitchell, ... Leukemia 33 (4), 981-994, 2019 | 130 | 2019 |
Megakaryocytes assemble podosomes that degrade matrix and protrude through basement membrane H Schachtner, SDJ Calaminus, A Sinclair, J Monypenny, MP Blundell, ... Blood, The Journal of the American Society of Hematology 121 (13), 2542-2552, 2013 | 129 | 2013 |
Rapid regulation of PDE-2 and PDE-4 cyclic AMP phosphodiesterase activity following ligation of the T cell antigen receptor on thymocytes: analysis using the selective … AM Michie, M Lobban, T Müller, MM Harnett, MD Houslay Cellular signalling 8 (2), 97-110, 1996 | 108 | 1996 |
The link between PKCα regulation and cellular transformation AM Michie, R Nakagawa Immunology letters 96 (2), 155-162, 2005 | 97 | 2005 |
Complement deficiencies limit CD20 monoclonal antibody treatment efficacy in CLL O Middleton, E Cosimo, E Dobbin, AM McCaig, C Clarke, AM Brant, ... Leukemia 29 (1), 107-114, 2015 | 89 | 2015 |
Dasatinib inhibits B cell receptor signalling in chronic lymphocytic leukaemia but novel combination approaches are required to overcome additional pro‐survival … AM MCCaig, E Cosimo, MT Leach, AM Michie British journal of haematology 153 (2), 199-211, 2011 | 89 | 2011 |
Natural killer cell development and function precede αβ T cell differentiation in mouse fetal thymic ontogeny JR Carlyle, AM Michie, SK Cho, JC Zúñiga-Pflücker The Journal of Immunology 160 (2), 744-753, 1998 | 85 | 1998 |
CML cells actively evade host immune surveillance through cytokine-mediated downregulation of MHC-II expression A Tarafdar, LEM Hopcroft, P Gallipoli, F Pellicano, J Cassels, A Hair, ... Blood, The Journal of the American Society of Hematology 129 (2), 199-208, 2017 | 82 | 2017 |
Allelic exclusion and differentiation by protein kinase C-mediated signals in immature thymocytes AM Michie, JW Soh, RG Hawley, IB Weinstein, JC Zúñiga-Pflücker Proceedings of the National Academy of Sciences 98 (2), 609-614, 2001 | 71 | 2001 |
CXCR2 and CXCL4 regulate survival and self-renewal of hematopoietic stem/progenitor cells A Sinclair, L Park, M Shah, M Drotar, S Calaminus, LEM Hopcroft, ... Blood, The Journal of the American Society of Hematology 128 (3), 371-383, 2016 | 70 | 2016 |
Extracellular Signal–regulated Kinase (ERK) Activation by the Pre-T Cell Receptor in Developing Thymocytes In Vivo AM Michie, S Trop, DL Wiest, JC Zúñiga-Pflücker The Journal of experimental medicine 190 (11), 1647-1656, 1999 | 68 | 1999 |
Subversion of Protein Kinase Cα Signaling in Hematopoietic Progenitor Cells Results in the Generation of a B-Cell Chronic Lymphocytic Leukemia–Like Population In vivo R Nakagawa, JW Soh, AM Michie Cancer Research 66 (1), 527-534, 2006 | 55 | 2006 |