Artykuły udostępnione publicznie: - Richard KocheWięcej informacji
Niedostępne w żadnym miejscu: 3
Sprawdź
Reply to "Uveal melanoma cells are resistant to EZH2 inhibition regardless of BAP1 status"
LM LaFave, W Béguelin, R Koche, M Teater, B Spitzer, A Chramiec, ...
Nature medicine 22 (6), 578-579, 2016
Upoważnienia: US National Institutes of Health, National Institute of Health and Medical …
Sprawdź
TGF-β and RAS jointly unmask primed enhancers to drive metastasis
JH Lee, FJ Sánchez-Rivera, L He, H Basnet, FX Chen, E Spina, L Li, ...
Cell 187 (22), 6182-6199. e29, 2024
Upoważnienia: Howard Hughes Medical Institute
Sprawdź
CRISPR Dependency Screens in Primary Hematopoietic Stem Cells Identify KDM3B as a Genotype-specific Vulnerability in IDH2- and TET2-mutant Cells
MR Waarts, S Mowla, M Boileau, AR Martinez Benitez, J Sango, M Bagish, ...
Cancer Discovery 14 (10), 1860-1878, 2024
Upoważnienia: Fonds de recherche du Québec - Santé
Dostępne w jakimś miejscu: 130
Sprawdź
Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains
M Ku, RP Koche, E Rheinbay, EM Mendenhall, M Endoh, TS Mikkelsen, ...
PLoS genetics 4 (10), e1000242, 2008
Upoważnienia: US National Institutes of Health
Sprawdź
ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression
O Abdel-Wahab, M Adli, LM LaFave, J Gao, T Hricik, AH Shih, S Pandey, ...
Cancer cell 22 (2), 180-193, 2012
Upoważnienia: US National Institutes of Health, Howard Hughes Medical Institute
Sprawdź
GC-rich sequence elements recruit PRC2 in mammalian ES cells
EM Mendenhall, RP Koche, T Truong, VW Zhou, B Issac, AS Chi, M Ku, ...
PLoS genetics 6 (12), e1001244, 2010
Upoważnienia: US National Institutes of Health, Howard Hughes Medical Institute
Sprawdź
Reprogramming factor expression initiates widespread targeted chromatin remodeling
RP Koche, ZD Smith, M Adli, H Gu, M Ku, A Gnirke, BE Bernstein, ...
Cell stem cell 8 (1), 96-105, 2011
Upoważnienia: US National Institutes of Health, Howard Hughes Medical Institute
Sprawdź
Loss of BAP1 function leads to EZH2-dependent transformation
LM LaFave, W Béguelin, R Koche, M Teater, B Spitzer, A Chramiec, ...
Nature medicine 21 (11), 1344-1349, 2015
Upoważnienia: US National Institutes of Health
Sprawdź
Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo
O Abdel-Wahab, J Gao, M Adli, A Dey, T Trimarchi, YR Chung, C Kuscu, ...
Journal of Experimental Medicine 210 (12), 2641-2659, 2013
Upoważnienia: US National Institutes of Health, Howard Hughes Medical Institute
Sprawdź
Dual targeting of oncogenic activation and inflammatory signaling increases therapeutic efficacy in myeloproliferative neoplasms
M Kleppe, R Koche, L Zou, P van Galen, CE Hill, L Dong, S De Groote, ...
Cancer cell 33 (1), 29-43. e7, 2018
Upoważnienia: US National Institutes of Health, European Molecular Biology Laboratory
Sprawdź
Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma
RP Koche, E Rodriguez-Fos, K Helmsauer, M Burkert, IC MacArthur, ...
Nature genetics 52 (1), 29-34, 2020
Upoważnienia: US National Institutes of Health, German Research Foundation
Sprawdź
DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling
OA Guryanova, K Shank, B Spitzer, L Luciani, RP Koche, ...
Nature medicine 22 (12), 1488-1495, 2016
Upoważnienia: US National Institutes of Health, Austrian Science Fund, Wellcome Trust
Sprawdź
α-Ketoglutarate links p53 to cell fate during tumour suppression
JP Morris IV, JJ Yashinskie, R Koche, R Chandwani, S Tian, CC Chen, ...
Nature 573 (7775), 595-599, 2019
Upoważnienia: US National Institutes of Health, Howard Hughes Medical Institute …
Sprawdź
Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia
MWM Kühn, E Song, Z Feng, A Sinha, CW Chen, AJ Deshpande, ...
Cancer discovery 6 (10), 1166-1181, 2016
Upoważnienia: US National Institutes of Health, German Research Foundation, UK Medical …
Sprawdź
DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia
CW Chen, RP Koche, AU Sinha, AJ Deshpande, N Zhu, R Eng, ...
Nature medicine 21 (4), 335-343, 2015
Upoważnienia: US National Institutes of Health
Sprawdź
A UTX-MLL4-p300 transcriptional regulatory network coordinately shapes active enhancer landscapes for eliciting transcription
SP Wang, Z Tang, CW Chen, M Shimada, RP Koche, LH Wang, ...
Molecular cell 67 (2), 308-321. e6, 2017
Upoważnienia: US National Institutes of Health, Human Frontier Science Program
Sprawdź
A gene–environment-induced epigenetic program initiates tumorigenesis
D Alonso-Curbelo, YJ Ho, C Burdziak, JLV Maag, JP Morris IV, ...
Nature 590 (7847), 642-648, 2021
Upoważnienia: US National Institutes of Health, Howard Hughes Medical Institute, Banking …
Sprawdź
L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer
K Ganesh, H Basnet, Y Kaygusuz, AM Laughney, L He, R Sharma, ...
Nature cancer 1 (1), 28-45, 2020
Upoważnienia: US Department of Defense, US National Institutes of Health, Wellcome Trust …
Sprawdź
Targeting MYCN-driven transcription by BET-bromodomain inhibition
A Henssen, K Althoff, A Odersky, A Beckers, R Koche, F Speleman, ...
Clinical Cancer Research 22 (10), 2470-2481, 2016
Upoważnienia: Research Foundation (Flanders)
Sprawdź
AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes
AJ Deshpande, A Deshpande, AU Sinha, L Chen, J Chang, A Cihan, ...
Cancer cell 26 (6), 896-908, 2014
Upoważnienia: US National Institutes of Health
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