The intracellular environment affects protein–protein interactions SL Speer, W Zheng, X Jiang, IT Chu, AJ Guseman, M Liu, GJ Pielak, C Li Proceedings of the National Academy of Sciences 118 (11), e2019918118, 2021 | 76 | 2021 |
The G-quadruplex fluorescent probe 3, 6-bis (1-methyl-2-vinyl-pyridinium) carbazole diiodide as a biosensor for human cancers TY Tseng, WW Chen, IT Chu, CL Wang, CC Chang, MC Lin, PJ Lou, ... Scientific Reports 8 (1), 16082, 2018 | 44 | 2018 |
Expression of the human telomerase reverse transcriptase gene is modulated by quadruplex formation in its first exon due to DNA methylation PT Li, ZF Wang, IT Chu, YM Kuan, MH Li, MC Huang, PC Chiang, ... Journal of Biological Chemistry 292 (51), 20859-20870, 2017 | 42 | 2017 |
Binding of Small Molecules to G-quadruplex DNA in Cells Revealed by Fluorescence Lifetime Imaging Microscopy of o-BMVC Foci TY Tseng, IT Chu, SJ Lin, J Li, TC Chang Molecules 24 (1), 35, 2018 | 23 | 2018 |
Rheostatic control of protein expression using Tuner cells IT Chu, SL Speer, GJ Pielak Biochemistry 59 (6), 733-735, 2020 | 12 | 2020 |
Macromolecular crowding by polyethylene glycol reduces protein breathing IT Chu, BO Hutcheson, HR Malsch, GJ Pielak The Journal of Physical Chemistry Letters 14 (10), 2599-2605, 2023 | 11 | 2023 |
A G-Quadruplex Structure in the Promoter Region of CLIC4 Functions as a Regulatory Element for Gene Expression MC Huang, IT Chu, ZF Wang, S Lin, TC Chang, CT Chen International Journal of Molecular Sciences 19 (9), 2678, 2018 | 11 | 2018 |
Effects of Length and Loop Composition on Structural Diversity and Similarity of (G3TG3NmG3TG3) G-Quadruplexes J Li, IT Chu, TA Yeh, DY Chen, CL Wang, TC Chang Molecules 25 (8), 1779, 2020 | 10 | 2020 |
Cytosine epigenetic modification modulates the formation of an unprecedented G4 structure in the WNT1 promoter ZF Wang, MH Li, IT Chu, FR Winnerdy, AT Phan, TC Chang Nucleic acids research 48 (3), 1120-1130, 2020 | 10 | 2020 |
A Difference between In Vitro and In-Cell Protein Dimer Formation IT Chu, CJ Stewart, SL Speer, GJ Pielak Biochemistry 61 (6), 409-412, 2022 | 9 | 2022 |
Using NMR-detected hydrogen-deuterium exchange to quantify protein stability in cosolutes, under crowded conditions in vitro and in cells IT Chu, GJ Pielak Magnetic Resonance Letters 3 (4), 319-326, 2023 | 7 | 2023 |
G-quadruplex formation by single-base mutation or deletion of mitochondrial DNA sequences IT Chu, CC Wu, TC Chang Biochimica et Biophysica Acta (BBA)-General Subjects 1863 (2), 418-425, 2019 | 6 | 2019 |
A tetramer of BCL11A is required for stable protein production and fetal hemoglobin silencing G Zheng, M Yin, S Mehta, IT Chu, S Wang, A AlShaye, K Drainville, ... Science 386 (6725), 1010-1018, 2024 | 1 | 2024 |
Comparison and elucidation of structural diversity and variation of G-rich sequences with a single G-base difference IT Chu, TY Tseng, TC Chang The Journal of Physical Chemistry B 123 (26), 5423-5431, 2019 | 1 | 2019 |
Protein Stability in Cells and Under Crowded Conditions in Vitro IT Chu The University of North Carolina at Chapel Hill, 2023 | | 2023 |
Protein dimer formation in vitro and in cells IT Chu, C Stewart, S Speer, G Pielak PROTEIN SCIENCE 32, 2023 | | 2023 |
Fluorescence of carbazole derivatives for screening of human cancer TY Tseng, WW Chen, IT Chu, CL Wang, CC Chang, MC Lin, PJ Lou, ... Optical Imaging, Therapeutics, and Advanced Technology in Head and Neck …, 2019 | | 2019 |