| Integrative Clinical Genomics of Advanced Prostate Cancer D Robinson, EM Van Allen, YM Wu, N Schultz, RJ Lonigro, JM Mosquera, ... Cell 161 (5), 1215-1228, 2015 | 3963 | 2015 |
| The molecular taxonomy of primary prostate cancer A Abeshouse, J Ahn, R Akbani, A Ally, S Amin, CD Andry, M Annala, ... Cell 163 (4), 1011-1025, 2015 | 2813 | 2015 |
| Evolution of genes and genomes on the Drosophila phylogeny AG Clark, MB Eisen, DR Smith, CM Bergman, B Oliver, TA Markow, ... Nature 450 (7167), 203-218, 2007 | 2283 | 2007 |
| < i> Braveheart</i>, a Long Noncoding RNA Required for Cardiovascular Lineage Commitment CA Klattenhoff, JC Scheuermann, LE Surface, RK Bradley, PA Fields, ... Cell 152 (3), 570-583, 2013 | 1070 | 2013 |
| RNA splicing factors as oncoproteins and tumour suppressors H Dvinge, E Kim, O Abdel-Wahab, RK Bradley Nature Reviews Cancer 16 (7), 413-430, 2016 | 705 | 2016 |
| SRSF2 mutations contribute to myelodysplasia by mutant-specific effects on exon recognition E Kim, JO Ilagan, Y Liang, GM Daubner, SCW Lee, A Ramakrishnan, Y Li, ... Cancer Cell 27 (5), 617-630, 2015 | 650 | 2015 |
| Fast statistical alignment RK Bradley, A Roberts, M Smoot, S Juvekar, J Do, C Dewey, I Holmes, ... PLoS computational biology 5 (5), e1000392, 2009 | 422 | 2009 |
| Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins SCW Lee, H Dvinge, E Kim, H Cho, JB Micol, YR Chung, BH Durham, ... Nature medicine 22 (6), 672-678, 2016 | 392 | 2016 |
| Widespread intron retention diversifies most cancer transcriptomes H Dvinge, RK Bradley Genome Medicine 7 (1), 45, 2015 | 367 | 2015 |
| U2AF1 mutations alter splice site recognition in hematological malignancies JO Ilagan, A Ramakrishnan, B Hayes, ME Murphy, AS Zebari, P Bradley, ... Genome research 25 (1), 14-26, 2015 | 330 | 2015 |
| RNA splicing dysregulation and the hallmarks of cancer RK Bradley, O Anczuków Nature Reviews Cancer, 1-21, 2023 | 250 | 2023 |
| Binding site turnover produces pervasive quantitative changes in transcription factor binding between closely related Drosophila species RK Bradley, XY Li, C Trapnell, S Davidson, L Pachter, HC Chu, LA Tonkin, ... PLoS biology 8 (3), e1000343, 2010 | 239 | 2010 |
| Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations SCW Lee, K North, E Kim, E Jang, E Obeng, SX Lu, B Liu, D Inoue, ... Cancer Cell 34 (2), 225-241. e8, 2018 | 231 | 2018 |
| Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis A Yoshimi, KT Lin, DH Wiseman, MA Rahman, A Pastore, B Wang, ... Nature 574 (7777), 273-277, 2019 | 212 | 2019 |
| Spliceosomal disruption of the non-canonical BAF complex in cancer D Inoue, GL Chew, B Liu, BC Michel, J Pangallo, AR D’Avino, T Hitchman, ... Nature 574 (7778), 432-436, 2019 | 211 | 2019 |
| Pharmacologic modulation of RNA splicing enhances anti-tumor immunity SX Lu, E De Neef, JD Thomas, E Sabio, B Rousseau, M Gigoux, DA Knorr, ... Cell 184 (15), 4032-4047. e31, 2021 | 206 | 2021 |
| Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer LF Escobar-Hoyos, A Penson, R Kannan, H Cho, CH Pan, RK Singh, ... Cancer cell 38 (2), 198-211. e8, 2020 | 153 | 2020 |
| Massive Mitochondrial Gene Transfer in a Parasitic Flowering Plant Clade Z Xi, Y Wang, RK Bradley, M Sugumaran, CJ Marx, JS Rest, CC Davis PLOS Genetics 9 (2), e1003265, 2013 | 149 | 2013 |
| RNA components of the spliceosome regulate tissue-and cancer-specific alternative splicing H Dvinge, J Guenthoer, PL Porter, RK Bradley Genome research 29 (10), 1591-1604, 2019 | 148 | 2019 |
| Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF5A CG Hubert, RK Bradley, Y Ding, CM Toledo, J Herman, K Skutt-Kakaria, ... Genes & development 27 (9), 1032-1045, 2013 | 141 | 2013 |
