Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression G Lagger, D O'Carroll, M Rembold, H Khier, J Tischler, G Weitzer, ... The EMBO journal 21 (11), 2672-2681, 2002 | 998 | 2002 |
Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways B Lehner, C Crombie, J Tischler, A Fortunato, AG Fraser Nature genetics 38 (8), 896-903, 2006 | 606 | 2006 |
Negative and positive regulation of gene expression by mouse histone deacetylase 1 G Zupkovitz, J Tischler, M Posch, I Sadzak, K Ramsauer, G Egger, ... Molecular and cellular biology 26 (21), 7913-7928, 2006 | 377 | 2006 |
Dynamic heterogeneity and DNA methylation in embryonic stem cells ZS Singer, J Yong, J Tischler, JA Hackett, A Altinok, MA Surani, L Cai, ... Molecular cell 55 (2), 319-331, 2014 | 315 | 2014 |
The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene G Lagger, A Doetzlhofer, B Schuettengruber, E Haidweger, E Simboeck, ... Molecular and cellular biology 23 (8), 2669-2679, 2003 | 259 | 2003 |
The cyclin-dependent kinase inhibitor p21 is a crucial target for histone deacetylase 1 as a regulator of cellular proliferation G Zupkovitz, R Grausenburger, R Brunmeir, S Senese, J Tischler, J Jurkin, ... Molecular and cellular biology 30 (5), 1171-1181, 2010 | 180 | 2010 |
Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation N Grabole, J Tischler, JA Hackett, S Kim, F Tang, HG Leitch, ... EMBO reports 14 (7), 629-637, 2013 | 177 | 2013 |
RNAi screens in Caenorhabditis elegans in a 96-well liquid format and their application to the systematic identification of genetic interactions B Lehner, J Tischler, AG Fraser Nature protocols 1 (3), 1617-1620, 2006 | 155 | 2006 |
Evolutionary plasticity of genetic interaction networks J Tischler, B Lehner, AG Fraser Nature genetics 40 (4), 390-391, 2008 | 152 | 2008 |
Combinatorial RNA interference in Caenorhabditis elegans reveals that redundancy between gene duplicates can be maintained for more than 80 million years of evolution J Tischler, B Lehner, N Chen, AG Fraser Genome biology 7 (8), 1-13, 2006 | 118 | 2006 |
Loss of LIN-35, the Caenorhabditis elegansortholog of the tumor suppressor p105Rb, results in enhanced RNA interference B Lehner, A Calixto, C Crombie, J Tischler, A Fortunato, M Chalfie, ... Genome biology 7 (1), 1-10, 2006 | 110 | 2006 |
Metabolic regulation of pluripotency and germ cell fate through α‐ketoglutarate J Tischler, WH Gruhn, J Reid, E Allgeyer, F Buettner, C Marr, F Theis, ... The EMBO journal 38 (1), e99518, 2019 | 99 | 2019 |
Single inner cell masses yield embryonic stem cell lines differing in lifr expression and their developmental potential M Lauss, M Stary, J Tischler, G Egger, S Puz, A Bader-Allmer, C Seiser, ... Biochemical and biophysical research communications 331 (4), 1577-1586, 2005 | 43 | 2005 |
Investigating transcriptional states at single-cell-resolution J Tischler, MA Surani Current opinion in biotechnology 24 (1), 69-78, 2013 | 40 | 2013 |
A sporadic super state A Surani, J Tischler Nature 487 (7405), 43-44, 2012 | 31 | 2012 |
An automated do-it-yourself system for dynamic stem cell and organoid culture in standard multi-well plates J Tischler, Z Swank, HA Hsiung, S Vianello, MP Lutolf, SJ Maerkl Cell reports methods 2 (7), 100244, 2022 | 13 | 2022 |
Systems biology: where it's at in 2005 B Lehner, J Tischler, AG Fraser Genome Biology 6 (8), 1-4, 2005 | 9 | 2005 |