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Ludmil B. Alexandrov
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Signatures of mutational processes in human cancer
LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ...
Nature 500 (7463), 415-421, 2013
106242013
The repertoire of mutational signatures in human cancer
LB Alexandrov, J Kim, NJ Haradhvala, MN Huang, AW Tian Ng, Y Wu, ...
Nature 578 (7793), 94-101, 2020
30612020
Landscape of somatic mutations in 560 breast cancer whole-genome sequences
S Nik-Zainal, H Davies, J Staaf, M Ramakrishna, D Glodzik, X Zou, ...
Nature 534 (7605), 47-54, 2016
23642016
Mutational Processes Molding the Genomes of 21 Breast Cancers
S Nik-Zainal, LB Alexandrov, DC Wedge, P Van Loo, CD Greenman, ...
Cell 149 (5), 979-993, 2012
21752012
High burden and pervasive positive selection of somatic mutations in normal human skin
I Martincorena, A Roshan, M Gerstung, P Ellis, P Van Loo, S McLaren, ...
Science 348 (6237), 880-886, 2015
18832015
Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets
K Schulze, S Imbeaud, E Letouzé, LB Alexandrov, J Calderaro, ...
Nature Genetics 47 (5), 505–511, 2015
17922015
Pan-cancer analysis of whole genomes
Nature 578 (7793), 82-93, 2020
17582020
The Life History of 21 Breast Cancers
S Nik-Zainal, P Van Loo, DC Wedge, LB Alexandrov, CD Greenman, ...
Cell 149 (5), 994-1007, 2012
16392012
The evolutionary history of lethal metastatic prostate cancer
G Gundem, P Van Loo, B Kremeyer, LB Alexandrov, JMC Tubio, ...
Nature 520 (7547), 353–357, 2015
15322015
Whole-genome landscapes of major melanoma subtypes
NK Hayward, JS Wilmott, N Waddell, PA Johansson, MA Field, K Nones, ...
Nature 545, 175–180, 2017
14162017
Deciphering Signatures of Mutational Processes Operative in Human Cancer
LB Alexandrov, S Nik-Zainal, DC Wedge, PJ Campbell, MR Stratton
Cell Reports 3 (1), 246-259, 2013
13452013
Mutational signatures associated with tobacco smoking in human cancer
LB Alexandrov, YS Ju, K Haase, P Van Loo, I Martincorena, S Nik-Zainal, ...
Science 354 (6312), 618-622, 2016
11392016
Clock-like mutational processes in human somatic cells
LB Alexandrov, PH Jones, DC Wedge, JE Sale, PJ Campbell, ...
Nature Genetics 47 (12), 1402–1407, 2015
10762015
Heterogeneity of genomic evolution and mutational profiles in multiple myeloma
N Bolli, H Avet-Loiseau, DC Wedge, P Van Loo, LB Alexandrov, ...
Nature Communications 5 (2997), 2014
10282014
Timing, rates and spectra of human germline mutation
R Rahbari, A Wuster, SJ Lindsay, RJ Hardwick, LB Alexandrov, S Al Turki, ...
Nature Genetics 48, 126–133, 2016
9712016
Subclonal diversification of primary breast cancer revealed by multiregion sequencing
LR Yates, M Gerstung, S Knappskog, C Desmedt, G Gundem, P Van Loo, ...
Nature Medicine 21 (7), 751-759, 2015
8702015
Whole-genome and epigenomic landscapes of etiologically distinct subtypes of cholangiocarcinoma
A Jusakul, I Cutcutache, CH Yong, JQ Lim, MN Huang, N Padmanabhan, ...
Cancer discovery 7 (10), 1116-1135, 2017
8412017
Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours
X Ma, YU Liu, Y Liu, LB Alexandrov, MN Edmonson, C Gawad, X Zhou, ...
Nature 555 (7696), 371-376, 2018
8272018
Genomic evolution of breast cancer metastasis and relapse
LR Yates, S Knappskog, D Wedge, JHR Farmery, S Gonzalez, ...
Cancer cell 32 (2), 169-184. e7, 2017
7152017
A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns
F Notta, M Chan-Seng-Yue, M Lemire, Y Li, GW Wilson, AA Connor, ...
Nature 538, 378–382, 2016
6062016
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