Traver Hart

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Jason MoffatSenior Scientist & Program Head, Genetics & Genome Biology, Sickkids Hospital; Professor, UofTZweryfikowany adres z utoronto.ca
Stephane AngersDirector and Professor, Donnelly Centre, University of TorontoZweryfikowany adres z utoronto.ca
Edward MarcotteProfessor of Molecular Biosciences, University of Texas at AustinZweryfikowany adres z utexas.edu
Zachary SteinhartGladstone-UCSF Institute of Genomic ImmunologyZweryfikowany adres z gladstone.ucsf.edu
Kevin R BrownHospital for Sick ChildrenZweryfikowany adres z sickkids.ca
Daniel DurocherThe Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital and Department of MolecularZweryfikowany adres z lunenfeld.ca
Graham MacLeodUniversity of TorontoZweryfikowany adres z mail.utoronto.ca
Michael AreggerNational Cancer Institute (NCI), National Institutes of Health (NIH)Zweryfikowany adres z nih.gov
Amélie Fradet-TurcotteAssociate professor, Dept. of Molecular Biology, Medical Biochemistry and Pathology, UniversitéZweryfikowany adres z crchudequebec.ulaval.ca
Daniel R. BoutzHouston Methodist Research InstituteZweryfikowany adres z houstonmethodist.org
Olivia RisslandUniversity of Colorado School of MedicineZweryfikowany adres z ucdenver.edu
Frederick P (Fritz) RothUniversity of Pittsburgh School of Medicine, Department of Computational & Systems BiologyZweryfikowany adres z pitt.edu
Alberto PaccanaroProfessor at Royal Holloway, University of LondonZweryfikowany adres z cs.rhul.ac.uk
Peggy I WangNational Cancer InstituteZweryfikowany adres z nih.gov
Tamás NepuszDepartment of Biological Physics, Eötvös Loránd UniversityZweryfikowany adres z hal.elte.hu
Sadhna PhanseSenior Analyst, University of Regina, Oregon Health and Science UniversityZweryfikowany adres z ohsu.edu
Andrew EllingtonProfessor of Molecular Biosciences, Center for Systems and Synthetic Biology, University of Texas at AustinZweryfikowany adres z austin.utexas.edu
Arun Kumar RamaniInvitae

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Traver Hart

The University of Texas MD Anderson Cancer Center

Zweryfikowany adres z mdanderson.org - Strona główna

computational biology cancer genomics gene essentiality CRISPR/Cas9 screening


Tytuł Sortuj wg cytatów Sortuj wg roku Sortuj wg tytułu	Cytowane przez Cytowane przez	Rok
High-resolution CRISPR screens reveal fitness genes and genotype-specific cancer liabilities T Hart, M Chandrashekhar, M Aregger, Z Steinhart, KR Brown, ... Cell 163 (6), 1515-1526, 2015	1720	2015
A census of human soluble protein complexes PC Havugimana, GT Hart, T Nepusz, H Yang, AL Turinsky, Z Li, PI Wang, ... Cell 150 (5), 1068-1081, 2012	980	2012
The shieldin complex mediates 53BP1-dependent DNA repair SM Noordermeer, S Adam, D Setiaputra, M Barazas, SJ Pettitt, AK Ling, ... Nature 560 (7716), 117-121, 2018	615	2018
Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis X Liu, L Nie, Y Zhang, Y Yan, C Wang, M Colic, K Olszewski, A Horbath, ... Nature cell biology 25 (3), 404-414, 2023	608	2023
Evaluation and design of genome-wide CRISPR/SpCas9 knockout screens T Hart, AHY Tong, K Chan, J Van Leeuwen, A Seetharaman, M Aregger, ... G3: Genes, Genomes, Genetics 7 (8), 2719-2727, 2017	557	2017
How complete are current yeast and human protein-interaction networks? GT Hart, AK Ramani, EM Marcotte Genome biology 7, 1-9, 2006	532	2006
Measuring error rates in genomic perturbation screens: gold standards for human functional genomics T Hart, KR Brown, F Sircoulomb, R Rottapel, J Moffat Mol Syst Biol 10, 733, 2014	404	2014
CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions M Zimmermann, O Murina, MAM Reijns, A Agathanggelou, R Challis, ... Nature 559 (7713), 285-289, 2018	382	2018
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells KA Lawson, CM Sousa, X Zhang, E Kim, R Akthar, JJ Caumanns, Y Yao, ... Nature 586 (7827), 120-126, 2020	337	2020
Genome-wide CRISPR screens reveal a Wnt–FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors Z Steinhart, Z Pavlovic, M Chandrashekhar, T Hart, X Wang, X Zhang, ... Nature medicine 23 (1), 60-68, 2017	335	2017
A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality GT Hart, I Lee, EM Marcotte BMC bioinformatics 8, 1-11, 2007	291	2007
Finding the active genes in deep RNA-seq gene expression studies T Hart, HK Komori, S LaMere, K Podshivalova, DR Salomon BMC genomics 14, 1-7, 2013	280	2013
BAGEL: a computational framework for identifying essential genes from pooled library screens T Hart, J Moffat BMC bioinformatics 17, 1-7, 2016	275	2016
Genome-wide CRISPR-Cas9 screens expose genetic vulnerabilities and mechanisms of temozolomide sensitivity in glioblastoma stem cells G MacLeod, DA Bozek, N Rajakulendran, V Monteiro, M Ahmadi, ... Cell reports 27 (3), 971-986. e9, 2019	230	2019
HumanNet v2: human gene networks for disease research S Hwang, CY Kim, S Yang, E Kim, T Hart, EM Marcotte, I Lee Nucleic acids research 47 (D1), D573-D580, 2019	214	2019
Identifying chemogenetic interactions from CRISPR screens with drugZ M Colic, G Wang, M Zimmermann, K Mascall, M McLaughlin, L Bertolet, ... Genome medicine 11 (1), 1-12, 2019	197	2019
Genome-wide CRISPR-Cas9 screens reveal loss of redundancy between PKMYT1 and WEE1 in glioblastoma stem-like cells CM Toledo, Y Ding, P Hoellerbauer, RJ Davis, R Basom, EJ Girard, E Lee, ... Cell reports 13 (11), 2425-2439, 2015	192	2015
Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer L Aubert, N Nandagopal, Z Steinhart, G Lavoie, S Nourreddine, J Berman, ... Nature communications 11 (1), 3701, 2020	181	2020
Natural variation in gene expression modulates the severity of mutant phenotypes V Vu, AJ Verster, M Schertzberg, T Chuluunbaatar, M Spensley, D Pajkic, ... Cell 162 (2), 391-402, 2015	158	2015
Genome-wide CRISPR screens reveal synthetic lethality of RNASEH2 deficiency and ATR inhibition C Wang, G Wang, X Feng, P Shepherd, J Zhang, M Tang, Z Chen, ... Oncogene 38 (14), 2451-2463, 2019	131	2019

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