| The quest to slow ageing through drug discovery L Partridge, M Fuentealba, BK Kennedy Nature Reviews Drug Discovery 19 (8), 513-532, 2020 | 389 | 2020 |
| Common genetic associations between age-related diseases HM Dönertaş, DK Fabian, M Fuentealba, L Partridge, JM Thornton Nature aging 1 (4), 400-412, 2021 | 186 | 2021 |
| Gene expression‐based drug repurposing to target aging HM Dönertaş, M Fuentealba Valenzuela, L Partridge, JM Thornton Aging cell 17 (5), e12819, 2018 | 64 | 2018 |
| Functional conservation in genes and pathways linking ageing and immunity DK Fabian, M Fuentealba, HM Dönertaş, L Partridge, JM Thornton Immunity & Ageing 18 (1), 1-18, 2021 | 56 | 2021 |
| Using the drug-protein interactome to identify anti-ageing compounds for humans M Fuentealba, HM Dönertaş, R Williams, J Labbadia, JM Thornton, ... PLoS computational biology 15 (1), e1006639, 2019 | 45 | 2019 |
| Unfolded protein response IRE1/XBP1 signaling is required for healthy mammalian brain aging F Cabral‐Miranda, G Tamburini, G Martinez, AO Ardiles, DB Medinas, ... The EMBO Journal 41 (22), e111952, 2022 | 41 | 2022 |
| The unfolded protein response transcription factor XBP1s ameliorates Alzheimer’s disease by improving synaptic function and proteostasis C Duran-Aniotz, N Poblete, C Rivera-Krstulovic, ÁO Ardiles, ... Molecular Therapy, 2023 | 31 | 2023 |
| The Space Omics and Medical Atlas (SOMA) and international astronaut biobank EG Overbey, JK Kim, BT Tierney, J Park, N Houerbi, AG Lucaci, ... Nature, 1-3, 2024 | 27 | 2024 |
| Identifying potential ageing-modulating drugs in silico HM Dönertaş, M Fuentealba, L Partridge, JM Thornton Trends in Endocrinology & Metabolism 30 (2), 118-131, 2019 | 25 | 2019 |
| Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight JK Kim, BT Tierney, EG Overbey, E Dantas, M Fuentealba, J Park, ... Nature Communications 15 (1), 4954, 2024 | 24 | 2024 |
| The neuronal receptor tyrosine kinase Alk is a target for longevity NS Woodling, B Aleyakpo, MC Dyson, LJ Minkley, A Rajasingam, ... Aging Cell 19 (5), e13137, 2020 | 24 | 2020 |
| Modeling the interfacial interactions between CrtS and CrtR from Xanthophyllomyces dendrorhous, a P450 system involved in astaxanthin production J Alcaı́no, M Fuentealba, R Cabrera, M Baeza, V Cifuentes Journal of agricultural and food chemistry 60 (35), 8640-8647, 2012 | 23 | 2012 |
| Metabolic impact of an NADH-producing glucose-6-phosphate dehydrogenase in Escherichia coli K Olavarria, J De Ingeniis, DC Zielinski, M Fuentealba, R Muñoz, ... Microbiology 160 (12), 2780-2793, 2014 | 22 | 2014 |
| Determinants of Cofactor Specificity for the Glucose-6-Phosphate Dehydrogenase from Escherichia coli: Simulation, Kinetics and Evolutionary Studies M Fuentealba, R Muñoz, P Maturana, A Krapp, R Cabrera PloS one 11 (3), e0152403, 2016 | 18 | 2016 |
| Single-cell analysis identifies conserved features of immune dysfunction in simulated microgravity and spaceflight F Wu, H Du, E Overbey, JK Kim, P Makhijani, N Martin, CA Lerner, ... Nature Communications 15 (1), 4795, 2024 | 12 | 2024 |
| Transcriptomic profiling of long-and short-lived mutant mice implicates mitochondrial metabolism in ageing and shows signatures of normal ageing in progeroid mice M Fuentealba, DK Fabian, HM Dönertaş, JM Thornton, L Partridge Mechanisms of ageing and development 194, 111437, 2021 | 10 | 2021 |
| Polyol specificity of recombinant Arabidopsis thaliana sorbitol dehydrogenase studied by enzyme kinetics and in silico modeling MF Aguayo, JC Cáceres, M Fuentealba, R Muñoz, C Stange, R Cabrera, ... Frontiers in plant science 6, 91, 2015 | 9 | 2015 |
| Transposable Element Landscape in Drosophila Populations Selected for Longevity DK Fabian, HM Dönertaş, M Fuentealba, L Partridge, JM Thornton Genome biology and evolution 13 (4), evab031, 2021 | 7 | 2021 |
| Crystal structure of the 6-phosphogluconate dehydrogenase from Gluconobacter oxydans reveals tetrameric 6PGDHs as the crucial intermediate in the … P Maturana, E Tobar-Calfucoy, M Fuentealba, P Roversi, R Garratt, ... Wellcome Open Research 6, 48, 2021 | 5 | 2021 |
| Human NLRC4 promotes cancer survival and is associated to type-I interferon signaling and immune infiltration C Domblides, S Crampton, H Liu, JM Bartleson, A Nguyen, C Champagne, ... The Journal of Clinical Investigation, 2024 | 3 | 2024 |