Microbiota transplantation restores normal fecal bile acid composition in recurrent Clostridium difficile infection AR Weingarden, C Chen, A Bobr, D Yao, Y Lu, VM Nelson, MJ Sadowsky, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 306 (4 …, 2014 | 555 | 2014 |
Activation of antioxidant-response element (ARE), mitogen-activated protein kinases (MAPKs) and caspases by major green tea polyphenol components during cell survival and death C Chen, R Yu, ED Owuor, AN Tony Kong Archives of pharmacal research 23, 605-612, 2000 | 530 | 2000 |
Induction of xenobiotic enzymes by the map kinase pathway and the antioxidant or electrophile response element (ARE/EpRE),†,‡ ANT Kong, E Owuor, R Yu, V Hebbar, C Chen, R Hu, S Mandlekar Drug metabolism reviews 33 (3-4), 255-271, 2001 | 429 | 2001 |
Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism R Yu, C Chen, YY Mo, V Hebbar, ED Owuor, TH Tan, ANT Kong Journal of Biological Chemistry 275 (51), 39907-39913, 2000 | 420 | 2000 |
Suppression of NF-κB and NF-κB-regulated gene expression by sulforaphane and PEITC through IκBα, IKK pathway in human prostate cancer PC-3 cells C Xu, G Shen, C Chen, C Gélinas, ANT Kong Oncogene 24 (28), 4486-4495, 2005 | 384* | 2005 |
Dietary cancer-chemopreventive compounds: from signaling and gene expression to pharmacological effects C Chen, ANT Kong Trends in pharmacological sciences 26 (6), 318-326, 2005 | 370 | 2005 |
Induction of detoxifying enzymes by garlic organosulfur compounds through transcription factor Nrf2: effect of chemical structure and stress signals C Chen, D Pung, V Leong, V Hebbar, G Shen, S Nair, W Li, ANT Kong Free Radical Biology and Medicine 37 (10), 1578-1590, 2004 | 352 | 2004 |
Signal transduction events elicited by natural products: role of MAPK and caspase pathways in homeostatic response and induction of apoptosis ANT Kong, R Yu, C Chen, S Mandlekar, T Primiano Archives of pharmacal research 23, 1-16, 2000 | 338 | 2000 |
LC-MS-based metabolomics in drug metabolism C Chen, FJ Gonzalez, JR Idle Drug metabolism reviews 39 (2-3), 581-597, 2007 | 325 | 2007 |
Epigallocatechin-3-gallate-induced stress signals in HT-29 human colon adenocarcinoma cells C Chen, G Shen, V Hebbar, R Hu, ED Owuor, ANT Kong Carcinogenesis 24 (8), 1369-1378, 2003 | 311 | 2003 |
Phytochemicals: cancer chemoprevention and suppression of tumor onset and metastasis L Shu, KL Cheung, TO Khor, C Chen, AN Kong Cancer and Metastasis Reviews 29, 483-502, 2010 | 307 | 2010 |
Dietary chemopreventive compounds and ARE/EpRE signaling C Chen, ANT Kong Free Radical Biology and Medicine 36 (12), 1505-1516, 2004 | 304 | 2004 |
In vivo pharmacokinetics and regulation of gene expression profiles by isothiocyanate sulforaphane in the rat R Hu, V Hebbar, BR Kim, C Chen, B Winnik, B Buckley, P Soteropoulos, ... The Journal of pharmacology and experimental therapeutics 310 (1), 263-271, 2004 | 283 | 2004 |
Opioid-induced gut microbial disruption and bile dysregulation leads to gut barrier compromise and sustained systemic inflammation S Banerjee, G Sindberg, F Wang, J Meng, U Sharma, L Zhang, P Dauer, ... Mucosal immunology 9 (6), 1418-1428, 2016 | 270 | 2016 |
Low-fat, high-fiber diet reduces markers of inflammation and dysbiosis and improves quality of life in patients with ulcerative colitis J Fritsch, L Garces, MA Quintero, J Pignac-Kobinger, AM Santander, ... Clinical gastroenterology and hepatology 19 (6), 1189-1199. e30, 2021 | 248 | 2021 |
Morphine induces changes in the gut microbiome and metabolome in a morphine dependence model F Wang, J Meng, L Zhang, T Johnson, C Chen, S Roy Scientific reports 8 (1), 3596, 2018 | 238 | 2018 |
Signal transduction events elicited by cancer prevention compounds ANT Kong, R Yu, V Hebbar, C Chen, E Owuor, R Hu, R Ee, S Mandlekar Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 480 …, 2001 | 217 | 2001 |
Cancer chemoprevention of intestinal polyposis in ApcMin/+ mice by sulforaphane, a natural product derived from cruciferous vegetable R Hu, TO Khor, G Shen, WS Jeong, V Hebbar, C Chen, C Xu, B Reddy, ... Carcinogenesis 27 (10), 2038-2046, 2006 | 216 | 2006 |
Serum metabolomics reveals irreversible inhibition of fatty acid β-oxidation through the suppression of PPARα activation as a contributing mechanism of acetaminophen-induced … C Chen, KW Krausz, YM Shah, JR Idle, FJ Gonzalez Chemical research in toxicology 22 (4), 699-707, 2009 | 203 | 2009 |
Metabolism, oral bioavailability and pharmacokinetics of chemopreventive kaempferol in rats A Barve, C Chen, V Hebbar, J Desiderio, CLL Saw, AN Kong Biopharmaceutics & drug disposition 30 (7), 356-365, 2009 | 198 | 2009 |