SirT1 regulates energy metabolism and response to caloric restriction in mice G Boily, EL Seifert, L Bevilacqua, XH He, G Sabourin, C Estey, C Moffat, ... PloS one 3 (3), e1759, 2008 | 561 | 2008 |
MICU1 controls both the threshold and cooperative activation of the mitochondrial Ca2+ uniporter G Csordás, T Golenár, EL Seifert, KJ Kamer, Y Sancak, F Perocchi, ... Cell metabolism 17 (6), 976-987, 2013 | 521 | 2013 |
Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics I Irrcher, H Aleyasin, EL Seifert, SJ Hewitt, S Chhabra, M Phillips, AK Lutz, ... Human molecular genetics 19 (19), 3734-3746, 2010 | 472 | 2010 |
Mitochondrial functions modulate neuroendocrine, metabolic, inflammatory, and transcriptional responses to acute psychological stress. WDC Picard M, McManus MJ, Gray JD, Nasca C, Moffat C, Kopinski PK, Seifert ... Proc Natl Acad Sci U S A 112, E6614-23, 2015 | 287* | 2015 |
Electron transport chain-dependent and-independent mechanisms of mitochondrial H2O2 emission during long-chain fatty acid oxidation EL Seifert, C Estey, JY Xuan, ME Harper Journal of Biological Chemistry 285 (8), 5748-5758, 2010 | 284 | 2010 |
Thyroid hormone effects on mitochondrial energetics ME Harper, EL Seifert Thyroid 18 (2), 145-156, 2008 | 227 | 2008 |
MICU1 regulation of mitochondrial Ca2+ uptake dictates survival and tissue regeneration AN Antony, M Paillard, C Moffat, E Juskeviciute, J Correnti, B Bolon, ... Nature communications 7 (1), 10955, 2016 | 210 | 2016 |
Tissue-specific mitochondrial decoding of cytoplasmic Ca2+ signals is controlled by the stoichiometry of MICU1/2 and MCU M Paillard, G Csordás, G Szanda, T Golenár, V Debattisti, A Bartok, ... Cell reports 18 (10), 2291-2300, 2017 | 204 | 2017 |
Glutathionylation acts as a control switch for uncoupling proteins UCP2 and UCP3 RJ Mailloux, EL Seifert, F Bouillaud, C Aguer, S Collins, ME Harper Journal of Biological Chemistry 286 (24), 21865-21875, 2011 | 202 | 2011 |
Uncoupling protein‐3: clues in an ongoing mitochondrial mystery V Bézaire, EL Seifert, ME Harper The FASEB Journal 21 (2), 312-324, 2007 | 176 | 2007 |
The retinal pigment epithelium utilizes fatty acids for ketogenesis: implications for metabolic coupling with the outer retina J Adijanto, J Du, C Moffat, EL Seifert, JB Hurley, NJ Philp Journal of Biological Chemistry 289 (30), 20570-20582, 2014 | 166 | 2014 |
Essential role for uncoupling protein-3 in mitochondrial adaptation to fasting but not in fatty acid oxidation or fatty acid anion export EL Seifert, V Bezaire, C Estey, ME Harper Journal of Biological Chemistry 283 (37), 25124-25131, 2008 | 125 | 2008 |
Posttranscriptional upregulation of IDH1 by HuR establishes a powerful survival phenotype in pancreatic cancer cells M Zarei, S Lal, SJ Parker, A Nevler, A Vaziri-Gohar, K Dukleska, ... Cancer research 77 (16), 4460-4471, 2017 | 115 | 2017 |
Hypoxia promotes noncanonical autophagy in nucleus pulposus cells independent of MTOR and HIF1A signaling H Choi, C Merceron, L Mangiavini, EL Seifert, E Schipani, IM Shapiro, ... Autophagy 12 (9), 1631-1646, 2016 | 113 | 2016 |
The SIRT1 deacetylase protects mice against the symptoms of metabolic syndrome AZ Caron, X He, W Mottawea, EL Seifert, K Jardine, D Dewar‐Darch, ... The FASEB Journal 28 (3), 1306-1316, 2014 | 97 | 2014 |
Decreased left ventricular function, myocarditis, and coronary arteriolar medial thickening following monocrotaline administration in adult rats F Akhavein, EJ St.-Michel, E Seifert, CV Rohlicek Journal of Applied Physiology 103 (1), 287-295, 2007 | 97 | 2007 |
Dysregulation of mitochondrial Ca2+ uptake and sarcolemma repair underlie muscle weakness and wasting in patients and mice lacking MICU1 V Debattisti, A Horn, R Singh, EL Seifert, MW Hogarth, DA Mazala, ... Cell reports 29 (5), 1274-1286. e6, 2019 | 94 | 2019 |
Acyl-CoA thioesterase-2 facilitates mitochondrial fatty acid oxidation in the liver C Moffat, L Bhatia, T Nguyen, P Lynch, M Wang, D Wang, OR Ilkayeva, ... Journal of lipid research 55 (12), 2458-2470, 2014 | 91 | 2014 |
Hypoxic depression of circadian rhythms in adult rats JP Mortola, EL Seifert Journal of Applied Physiology 88 (2), 365-368, 2000 | 91 | 2000 |
OxPhos defects cause hypermetabolism and reduce lifespan in cells and in patients with mitochondrial diseases G Sturm, KR Karan, AS Monzel, B Santhanam, T Taivassalo, C Bris, ... Communications biology 6 (1), 22, 2023 | 83 | 2023 |