The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING EJ Diner, DL Burdette, SC Wilson, KM Monroe, CA Kellenberger, ... Cell reports 3 (5), 1355-1361, 2013 | 840 | 2013 |
The cytosolic sensor cGAS detects Mycobacterium tuberculosis DNA to induce type I interferons and activate autophagy RO Watson, SL Bell, DA MacDuff, JM Kimmey, EJ Diner, J Olivas, ... Cell host & microbe 17 (6), 811-819, 2015 | 660 | 2015 |
A widespread family of polymorphic contact-dependent toxin delivery systems in bacteria SK Aoki, EJ Diner, CK de Roodenbeke, BR Burgess, SJ Poole, ... Nature 468 (7322), 439-442, 2010 | 358 | 2010 |
Identification of functional toxin/immunity genes linked to contact-dependent growth inhibition (CDI) and rearrangement hotspot (Rhs) systems SJ Poole, EJ Diner, SK Aoki, BA Braaten, C t'Kint de Roodenbeke, ... PLoS genetics 7 (8), e1002217, 2011 | 238 | 2011 |
Identification of a target cell permissive factor required for contact-dependent growth inhibition (CDI) EJ Diner, CM Beck, JS Webb, DA Low, CS Hayes Genes & development 26 (5), 515-525, 2012 | 128 | 2012 |
The toxin/immunity network of Burkholderia pseudomallei contact‐dependent growth inhibition (CDI) systems K Nikolakakis, S Amber, JS Wilbur, EJ Diner, SK Aoki, SJ Poole, ... Molecular microbiology 84 (3), 516-529, 2012 | 116 | 2012 |
Cyclic di-nucleotide induction of type i interferon RE Vance, MC Hammond, D Burdette, EJ Diner, SC Wilson US Patent App. 14/268,967, 2014 | 77 | 2014 |
Recombineering reveals a diverse collection of ribosomal proteins L4 and L22 that confer resistance to macrolide antibiotics EJ Diner, CS Hayes Journal of molecular biology 386 (2), 300-315, 2009 | 69 | 2009 |
Analysis of aminoacyl-and peptidyl-tRNAs by gel electrophoresis BD Janssen, EJ Diner, CS Hayes Bacterial Regulatory RNA: Methods and Protocols, 291-309, 2012 | 57 | 2012 |
APOBEC-1 and AID are nucleo-cytoplasmic trafficking proteins but APOBEC3G cannot traffic RP Bennett, E Diner, MP Sowden, JA Lees, JE Wedekind, HC Smith Biochemical and biophysical research communications 350 (1), 214-219, 2006 | 52 | 2006 |
The F pilus mediates a novel pathway of CDI toxin import CM Beck, EJ Diner, JJ Kim, DA Low, CS Hayes Molecular microbiology 93 (2), 276-290, 2014 | 26 | 2014 |
Taking the STING out of cytosolic DNA sensing EJ Diner, RE Vance Trends in immunology 35 (1), 1-2, 2014 | 20 | 2014 |
Genome engineering using targeted oligonucleotide libraries and functional selection EJ Diner, F Garza-Sánchez, CS Hayes Strain Engineering: Methods and Protocols, 71-82, 2011 | 12 | 2011 |
Cyclic Di-Nucleotide Induction of Type I Interferon RE Vance, MC Hammond, D Burdette, EJ Diner, SC Wilson US Patent App. 16/279,950, 2019 | 2 | 2019 |
Modified STING-activating cyclic dinucleotide derivatives significantly enhance the anti-tumor activity of therapeutic vaccines M Leong, D Kanne, L Glickman, E Lemmens, P Lauer, K Metchette, ... Journal for ImmunoTherapy of Cancer 1, 1-1, 2013 | 2 | 2013 |
Cyclic di-nucleotide induction of type i interferon D BURDETTE, RE Vance, MC HAMMOND, EJ DINER, SC Wilson | | 2014 |
Biochemical Characterization of Toxic Effector Domains from Contact-dependent Growth Inhibition (CDI) Systems EJ Diner University of California, Santa Barbara, 2011 | | 2011 |