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Frederik Eisele
Frederik Eisele
AstraZeneca
Zweryfikowany adres z gu.se
Tytuł
Cytowane przez
Cytowane przez
Rok
The cytoplasmic Hsp70 chaperone machinery subjects misfolded and endoplasmic reticulum import-incompetent proteins to degradation via the ubiquitin–proteasome system
SH Park, N Bolender, F Eisele, Z Kostova, J Takeuchi, P Coffino, DH Wolf
Molecular biology of the cell 18 (1), 153-165, 2007
2112007
Degradation of misfolded protein in the cytoplasm is mediated by the ubiquitin ligase Ubr1
F Eisele, DH Wolf
FEBS letters 582 (30), 4143-4146, 2008
1972008
FMN reduces Amyloid-β toxicity in yeast by regulating redox status and cellular metabolism
X Chen, B Ji, X Hao, X Li, F Eisele, T Nyström, D Petranovic
Nature Communications 11 (1), 867, 2020
632020
Opposing roles of U bp3‐dependent deubiquitination regulate replicative life span and heat resistance
D Öling, F Eisele, K Kvint, T Nyström
The EMBO journal 33 (7), 747-761, 2014
622014
Syntaxin 5 is required for the formation and clearance of protein inclusions during proteostatic stress
R Babazadeh, D Ahmadpour, S Jia, X Hao, P Widlund, K Schneider, ...
Cell reports 28 (8), 2096-2110. e8, 2019
412019
Bacterial genotoxin triggers FEN1-dependent RhoA activation, cytoskeleton remodeling and cell survival
L Guerra, R Guidi, I Slot, S Callegari, R Sompallae, CL Pickett, S Åström, ...
Journal of cell science 124 (16), 2735-2742, 2011
372011
An Hsp90 co-chaperone links protein folding and degradation and is part of a conserved protein quality control
F Eisele, AM Eisele-Bürger, X Hao, LL Berglund, JL Höög, B Liu, ...
Cell reports 35 (13), 2021
282021
Mutants of the deubiquitinating enzyme Ubp14 decipher pathway diversity of ubiquitin–proteasome linked protein degradation
F Eisele, B Braun, T Pfirrmann, DH Wolf
Biochemical and biophysical research communications 350 (2), 329-333, 2006
262006
Differential role of cytosolic Hsp70s in longevity assurance and protein quality control
R Andersson, AM Eisele-Bürger, S Hanzén, K Vielfort, D Öling, F Eisele, ...
PLoS genetics 17 (1), e1008951, 2021
222021
The Cdc48–Ufd1–Npl4 complex is central in ubiquitin–proteasome triggered catabolite degradation of fructose-1, 6-bisphosphatase
L Barbin, F Eisele, O Santt, DH Wolf
Biochemical and biophysical research communications 394 (2), 335-341, 2010
222010
Arabidopsis metacaspase MC1 localizes in stress granules, clears protein aggregates, and delays senescence
N Ruiz-Solaní, J Salguero-Linares, L Armengot, J Santos, I Pallarès, ...
The Plant Cell 35 (9), 3325-3344, 2023
162023
Rapid PROTAC discovery platform: nanomole-scale array synthesis and direct screening of reaction mixtures
MP Plesniak, EK Taylor, F Eisele, CMBK Kourra, IN Michaelides, A Oram, ...
ACS Medicinal Chemistry Letters 14 (12), 1882-1890, 2023
152023
Using reporters of different misfolded proteins reveals differential strategies in processing protein aggregates
KL Schneider, D Ahmadpour, KS Keuenhof, AM Eisele-Bürger, ...
Journal of Biological Chemistry 298 (11), 2022
122022
Ubiquitylation in the ERAD pathway
F Eisele, A Schäfer, DH Wolf
Conjugation and Deconjugation of Ubiquitin Family Modifiers: Subcellular …, 2010
112010
Optimization of Potent Ligands for the E3 Ligase DCAF15 and Evaluation of Their Use in Heterobifunctional Degraders
SCC Lucas, A Ahmed, SN Ashraf, A Argyrou, MR Bauer, GM De Donatis, ...
Journal of Medicinal Chemistry 67 (7), 5538-5566, 2024
32024
Components and mechanisms of cytoplasmic protein quality control and elimination of regulatory enzymes
F Eisele
32011
Calmodulin regulates protease versus co-chaperone activity of a metacaspase
AM Eisele-Bürger, F Eisele, SM Hill, X Hao, KL Schneider, R Imamoglu, ...
Cell Reports 42 (11), 2023
12023
Rapid PROTAC discovery platform: nanomole scale array synthesis and direct screening of reaction mixtures to facilitate the expedited discovery and follow-up of PROTAC hits.
M Plesniak, EK Taylor, F Eisele, CMBK Kourra, I Michaelides, A Oram, ...
12023
The cytoplasmic Hsp70 chaperone machinery subjects misfolded and ER import incompetent proteins to degradation via the ubiquitin-proteasome system.
SH Park, N Bolender, F Eisele, Z Kostova, J Takeuchi, P Coffino, DH Wolf
1
Unveiling the Power of PROTAC Valency: Navigating Cell Type-Specific Hook Effects
A Chitsazan, F Eisele, P Rabieifar, H Park, M Nordberg, J Liu, ...
bioRxiv, 2024.06. 12.598404, 2024
2024
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