NLRP3 inflammasome regulates development of systemic inflammatory response and compensatory anti-inflammatory response syndromes in mice with acute pancreatitis M Sendler, C van den Brandt, J Glaubitz, A Wilden, J Golchert, FU Weiss, ... Gastroenterology 158 (1), 253-269. e14, 2020 | 286 | 2020 |
Metabolic biomarker signature to differentiate pancreatic ductal adenocarcinoma from chronic pancreatitis J Mayerle, H Kalthoff, R Reszka, B Kamlage, E Peter, B Schniewind, ... Gut 67 (1), 128-137, 2018 | 270 | 2018 |
Cathepsin B-mediated activation of trypsinogen in endocytosing macrophages increases severity of pancreatitis in mice M Sendler, FU Weiss, J Golchert, G Homuth, C van den Brandt, ... Gastroenterology 154 (3), 704-718. e10, 2018 | 257 | 2018 |
Immune cell and stromal signature associated with progression-free survival of patients with resected pancreatic ductal adenocarcinoma UM Mahajan, E Langhoff, E Goni, E Costello, W Greenhalf, C Halloran, ... Gastroenterology 155 (5), 1625-1639. e2, 2018 | 178 | 2018 |
Complement component 5 mediates development of fibrosis, via activation of stellate cells, in 2 mouse models of chronic pancreatitis M Sendler, G Beyer, UM Mahajan, V Kauschke, S Maertin, C Schurmann, ... Gastroenterology 149 (3), 765-776. e10, 2015 | 104 | 2015 |
Tumour-specific delivery of siRNA-coupled superparamagnetic iron oxide nanoparticles, targeted against PLK1, stops progression of pancreatic cancer UM Mahajan, S Teller, M Sendler, R Palankar, C van den Brandt, ... Gut 65 (11), 1838-1849, 2016 | 95 | 2016 |
Development and validation of a chronic pancreatitis prognosis score in 2 independent cohorts G Beyer, UM Mahajan, C Budde, TJ Bulla, T Kohlmann, L Kuhlmann, ... Gastroenterology 153 (6), 1544-1554. e2, 2017 | 65 | 2017 |
Current strategies and future perspectives for precision medicine in pancreatic cancer I Regel, J Mayerle, M Ujjwal Mukund Cancers 12 (4), 1024, 2020 | 63 | 2020 |
Multifunctional gold nanorods for selective plasmonic photothermal therapy in pancreatic cancer cells using ultra-short pulse near-infrared laser irradiation T Patino, U Mahajan, R Palankar, N Medvedev, J Walowski, ... Nanoscale 7 (12), 5328-5337, 2015 | 55 | 2015 |
Identification and validation of a multivariable prediction model based on blood plasma and serum metabolomics for the distinction of chronic pancreatitis subjects from non … MG Adam, G Beyer, N Christiansen, B Kamlage, C Pilarsky, M Distler, ... Gut 70 (11), 2150-2158, 2021 | 44 | 2021 |
Ring1b-dependent epigenetic remodelling is an essential prerequisite for pancreatic carcinogenesis S Benitz, T Straub, UM Mahajan, J Mutter, S Czemmel, T Unruh, ... Gut 68 (11), 2007-2018, 2019 | 37 | 2019 |
Aptamers: a novel targeted theranostic platform for pancreatic ductal adenocarcinoma Q Li, SH Maier, P Li, J Peterhansl, C Belka, J Mayerle, UM Mahajan Radiation Oncology 15 (1), 189, 2020 | 34 | 2020 |
Tumor-specific delivery of 5-fluorouracil–incorporated epidermal growth factor receptor–targeted aptamers as an efficient treatment in pancreatic ductal adenocarcinoma models UM Mahajan, Q Li, A Alnatsha, J Maas, M Orth, SH Maier, J Peterhansl, ... Gastroenterology 161 (3), 996-1010. e1, 2021 | 33 | 2021 |
Independent validation and assay standardization of improved metabolic biomarker signature to differentiate pancreatic ductal adenocarcinoma from chronic pancreatitis UM Mahajan, B Oehrle, S Sirtl, A Alnatsha, E Goni, I Regel, G Beyer, ... Gastroenterology 163 (5), 1407-1422, 2022 | 29 | 2022 |
Alteration in inflammatory/apoptotic pathway and histone modifications by nordihydroguaiaretic acid prevents acute pancreatitis in swiss albino mice UM Mahajan, C Gupta, PR Wagh, PA Karpe, K Tikoo Apoptosis 16, 1138-1149, 2011 | 25 | 2011 |
Prediction of COVID-19 deterioration in high-risk patients at diagnosis: an early warning score for advanced COVID-19 developed by machine learning CEM Jakob, UM Mahajan, M Oswald, M Stecher, M Schons, J Mayerle, ... Infection, 1-12, 2021 | 24 | 2021 |
Early trypsin activation develops independently of autophagy in caerulein-induced pancreatitis in mice SR Malla, B Krueger, T Wartmann, M Sendler, UM Mahajan, FU Weiss, ... Cellular and Molecular Life Sciences 77, 1811-1825, 2020 | 23 | 2020 |
Epigenetic drug screening defines a PRMT5 inhibitor–sensitive pancreatic cancer subtype F Orben, K Lankes, C Schneeweis, Z Hassan, H Jakubowsky, L Krauß, ... JCI insight 7 (10), e151353, 2022 | 21 | 2022 |
Prevalence, resistance rates, and risk factors of pathogens in routine bile cultures obtained during endoscopic retrograde cholangiography FP Reiter, W Obermeier, J Jung, G Denk, UM Mahajan, EN De Toni, ... Digestive Diseases 39 (1), 42-51, 2021 | 20 | 2021 |
Downregulation of SFRP1 is a protumorigenic event in hepatoblastoma and correlates with beta-catenin mutations I Regel, M Eichenmüller, UM Mahajan, B Hagl, S Benitz, B Häberle, ... Journal of Cancer Research and Clinical Oncology 146, 1153-1167, 2020 | 20 | 2020 |