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Kelsey L. Swingle
Tytuł
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An ionizable lipid toolbox for RNA delivery
X Han, H Zhang, K Butowska, KL Swingle, MG Alameh, D Weissman, ...
Nature communications 12 (1), 7233, 2021
3832021
Orthogonal design of experiments for optimization of lipid nanoparticles for mRNA engineering of CAR T cells
MM Billingsley, AG Hamilton, D Mai, SK Patel, KL Swingle, NC Sheppard, ...
Nano letters 22 (1), 533-542, 2021
1172021
Nanoparticle protein corona: from structure and function to therapeutic targeting
G Bashiri, MS Padilla, KL Swingle, SJ Shepherd, MJ Mitchell, K Wang
Lab on a Chip 23 (6), 1432-1466, 2023
982023
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy
KL Swingle, HC Safford, HC Geisler, AG Hamilton, AS Thatte, ...
Journal of the American Chemical Society 145 (8), 4691-4706, 2023
912023
Lipid nanoparticle-mediated delivery of mRNA therapeutics and vaccines
KL Swingle*, AG Hamilton*, MJ Mitchell
Trends in molecular medicine 27 (6), 616-617, 2021
862021
Hydroxycholesterol substitution in ionizable lipid nanoparticles for mRNA delivery to T cells
SK Patel, MM Billingsley, C Frazee, X Han, KL Swingle, J Qin, MG Alameh, ...
Journal of Controlled Release 347, 521-532, 2022
762022
Platelet-mimicking procoagulant nanoparticles augment hemostasis in animal models of bleeding
UDS Sekhon, KL Swingle, A Girish, N Luc, M de la Fuente, J Alvikas, ...
Science translational medicine 14 (629), eabb8975, 2022
542022
Amniotic fluid stabilized lipid nanoparticles for in utero intra-amniotic mRNA delivery
KL Swingle, MM Billingsley, SK Bose, B White, R Palanki, A Dave, ...
Journal of Controlled Release 341, 616-633, 2022
542022
In vivo mRNA CAR T cell engineering via targeted ionizable lipid nanoparticles with extrahepatic tropism
MM Billingsley, N Gong, AJ Mukalel, AS Thatte, R El‐Mayta, SK Patel, ...
Small 20 (11), 2304378, 2024
532024
Ionizable Lipid Nanoparticles with Integrated Immune Checkpoint Inhibition for mRNA CAR T Cell Engineering
AG Hamilton, KL Swingle, RA Joseph, D Mai, N Gong, MM Billingsley, ...
Advanced Healthcare Materials, 2301515, 2023
452023
Ionizable lipid nanoparticles for therapeutic base editing of congenital brain disease
R Palanki, SK Bose, A Dave, BM White, C Berkowitz, V Luks, F Yaqoob, ...
ACS nano 17 (14), 13594-13610, 2023
422023
Biotechnology: overcoming biological barriers to nucleic acid delivery using lipid nanoparticles
AG Hamilton*, KL Swingle*, MJ Mitchell
PLoS Biology 21 (4), e3002105, 2023
332023
RGD peptide-based lipids for targeted mRNA delivery and gene editing applications
J Qin, L Xue, N Gong, H Zhang, SJ Shepherd, RM Haley, KL Swingle, ...
RSC advances 12 (39), 25397-25404, 2022
332022
Delivery technologies for women’s health applications
KL Swingle, AS Ricciardi, WH Peranteau, MJ Mitchell
Nature Reviews Bioengineering 1 (6), 408-425, 2023
292023
Orthogonal design of experiments for engineering of lipid nanoparticles for mRNA delivery to the placenta
HC Safford, KL Swingle, HC Geisler, AG Hamilton, AS Thatte, ...
Small 20 (41), 2303568, 2024
212024
mRNA Lipid Nanoparticles for Ex Vivo Engineering of Immunosuppressive T Cells for Autoimmunity Therapies
AS Thatte, AG Hamilton, BE Nachod, AJ Mukalel, MM Billingsley, ...
Nano Letters 23 (22), 10179-10188, 2023
132023
EGFR-targeted ionizable lipid nanoparticles enhance in vivo mRNA delivery to the placenta
HC Geisler, AA Ghalsasi, HC Safford, KL Swingle, AS Thatte, AJ Mukalel, ...
Journal of Controlled Release 371, 455-469, 2024
112024
High-Throughput In Vivo Screening Identifies Differential Influences on mRNA Lipid Nanoparticle Immune Cell Delivery by Administration Route
AG Hamilton, KL Swingle, AS Thatte, AJ Mukalel, HC Safford, ...
ACS nano 18 (25), 16151-16165, 2024
72024
Combinatorial design of siloxane-incorporated lipid nanoparticles augments intracellular processing for tissue-specific mRNA therapeutic delivery
L Xue, G Zhao, N Gong, X Han, SJ Shepherd, X Xiong, Z Xiao, R Palanki, ...
Nature Nanotechnology 20 (1), 132-143, 2025
52025
In utero delivery of targeted ionizable lipid nanoparticles facilitates in vivo gene editing of hematopoietic stem cells
R Palanki, JS Riley, SK Bose, V Luks, A Dave, N Kus, BM White, ...
Proceedings of the National Academy of Sciences 121 (32), e2400783121, 2024
52024
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