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Barrett Steinberg, Ph.D.
Barrett Steinberg, Ph.D.
Tessera Therapeutics, previously Editas Medicine, Johns Hopkins University
Zweryfikowany adres z tesseratx.com
Tytuł
Cytowane przez
Cytowane przez
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Environmental changes bridge evolutionary valleys
B Steinberg, M Ostermeier
Science advances 2 (1), e1500921, 2016
1282016
Shifting fitness and epistatic landscapes reflect trade-offs along an evolutionary pathway
B Steinberg, M Ostermeier
Journal of molecular biology 428 (13), 2730-2743, 2016
562016
Methods and compositions for modulating a genome
JR Rubens, GA Von Maltzahn, RJ Citorik, BE Steinberg, D Li, ...
US Patent 12,031,129, 2024
522024
Identification of guide-intrinsic determinants of Cas9 specificity
NC Huston, J Tycko, EL Tillotson, CJ Wilson, VE Myer, H Jayaram, ...
The CRISPR journal 2 (3), 172-185, 2019
192019
SMOOT libraries and phage-induced directed evolution of Cas9 to engineer reduced off-target activity
D Cerchione, K Loveluck, EL Tillotson, F Harbinski, J DaSilva, CP Kelley, ...
PLoS One 15 (4), e0231716, 2020
182020
Consequences of a telomerase-related fitness defect and chromosome substitution technology in yeast synIX strains
LH McCulloch, V Sambasivam, AL Hughes, N Annaluru, S Ramalingam, ...
Cell Genomics 3 (11), 2023
142023
Methods and compositions for modulating a genome
AH Bothmer, CGS Cotta-Ramusino, WE Salomon, JR Rubens, RJ Citorik, ...
US Patent App. 17/929,116, 2023
82023
Methods and compositions for modulating a genome
BE Steinberg, AH Bothmer, WE Salomon, I Shcherbakova, ...
US Patent App. 17/929,124, 2023
82023
Methods and compositions for modulating a genome
AH Bothmer, CGS Cotta-Ramusino, WE Salomon, JR Rubens, RJ Citorik, ...
US Patent App. 17/992,519, 2023
72023
Engineered Cas9 nucleases
BE Steinberg, D Cerchione
US Patent 10,428,319, 2019
72019
Systems and methods for one-shot guide RNA (ogRNA) targeting of endogenous and source DNA
AE Friedland, H Jayaram, BE Steinberg
US Patent 9,963,719, 2018
72018
Systems and methods for one-shot guide RNA (ogRNA) targeting of endogenous and source DNA
AE Friedland, H Jayaram, BE Steinberg
US Patent 10,006,054, 2018
52018
Methods and compositions for modulating a genome
RC Altshuler, AH Bothmer, CGS Cotta-Ramusino, RM Kotlar, ...
US Patent 12,037,617, 2024
42024
Methods and compositions for modulating a genome
RC Altshuler, AH Bothmer, CGS Cotta-Ramusino, RM Kotlar, ...
US Patent 12,031,162, 2024
42024
Methods and compositions for modulating a genome
S Cleaver, BE Steinberg, JR Rubens, RJ Citorik, WE Salomon, ZJ Wang
US Patent App. 17/929,455, 2024
42024
Engineered Cas9 nucleases
BE Steinberg, D Cerchione
US Patent 11,098,297, 2021
42021
Methods and compositions for modulating a genome
AH Bothmer, CGS Cotta-Ramusino, WE Salomon, JR Rubens, RJ Citorik, ...
US Patent App. 18/355,017, 2024
32024
Cftr-modulating compositions and methods
RC Altshuler, AH Bothmer, DR Chee, CGS Cotta-Ramusino, K Kim, ...
US Patent App. 18/470,687, 2024
22024
Pah-modulating compositions and methods
RC Altshuler, AH Bothmer, DR Chee, CGS Cotta-Ramusino, K Kim, ...
US Patent App. 18/495,276, 2024
22024
Serpina-modulating compositions and methods
RC Altshuler, AH Bothmer, DR Chee, CGS Cotta-Ramusino, K Kim, ...
US Patent App. 18/469,344, 2024
22024
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