| Deciding whether to go with the flow: evaluating the merits of flow reactors for synthesis RL Hartman, JP McMullen, KF Jensen Angewandte Chemie International Edition 50 (33), 7502-7519, 2011 | 1172 | 2011 |
| Integrated microreactors for reaction automation: new approaches to reaction development JP McMullen, KF Jensen Annual review of analytical chemistry 3 (1), 19-42, 2010 | 446 | 2010 |
| An integrated microreactor system for self‐optimization of a heck reaction: From micro‐to mesoscale flow systems JP McMullen, MT Stone, SL Buchwald, KF Jensen Angewandte Chemie 39 (122), 7230-7234, 2010 | 274 | 2010 |
| Palladium-catalyzed amination reactions in flow: overcoming the challenges of clogging via acoustic irradiation T Noël, JR Naber, RL Hartman, JP McMullen, KF Jensen, SL Buchwald Chemical Science 2 (2), 287-290, 2011 | 258 | 2011 |
| Rapid determination of reaction kinetics with an automated microfluidic system JP McMullen, KF Jensen Organic Process Research & Development 15 (2), 398-407, 2011 | 212 | 2011 |
| An automated microfluidic system for online optimization in chemical synthesis JP McMullen, KF Jensen Organic process research & development 14 (5), 1169-1176, 2010 | 178 | 2010 |
| Development of an automated microfluidic reaction platform for multidimensional screening: reaction discovery employing bicyclo [3.2. 1] octanoid scaffolds JR Goodell, JP McMullen, N Zaborenko, JR Maloney, CX Ho, KF Jensen, ... The Journal of organic chemistry 74 (16), 6169-6180, 2009 | 135 | 2009 |
| Pro und kontra Strömungsreaktoren in der Synthese RL Hartman, JP McMullen, KF Jensen Angewandte Chemie 123 (33), 7642-7661, 2011 | 130 | 2011 |
| Photon Equivalents as a Parameter for Scaling Photoredox Reactions in Flow: Translation of Photocatalytic C− N Cross‐Coupling from Lab Scale to Multikilogram Scale EB Corcoran, JP McMullen, F Lévesque, MK Wismer, JR Naber Angewandte Chemie International Edition 59 (29), 11964-11968, 2020 | 113 | 2020 |
| Manufacturing process development for belzutifan, part 2: a continuous flow visible-light-induced benzylic bromination C Bottecchia, F Levesque, JP McMullen, Y Ji, M Reibarkh, F Peng, L Tan, ... Organic Process Research & Development 26 (3), 516-524, 2021 | 65 | 2021 |
| Advancing flow chemistry portability: a simplified approach to scaling up flow chemistry F Lévesque, NJ Rogus, G Spencer, P Grigorov, JP McMullen, ... Organic Process Research & Development 22 (8), 1015-1021, 2018 | 43 | 2018 |
| Using flow to outpace fast proton transfer in an organometallic reaction for the manufacture of verubecestat (MK-8931) DA Thaisrivongs, JR Naber, JP McMullen Organic Process Research & Development 20 (11), 1997-2004, 2016 | 41 | 2016 |
| Multidimensional dynamic experiments for data-rich process development of reactions in flow BM Wyvratt, JP McMullen, ST Grosser Reaction Chemistry & Engineering 4 (9), 1637-1645, 2019 | 39 | 2019 |
| Benzylic photobromination for the synthesis of belzutifan: elucidation of reaction mechanisms using in situ LED-NMR Y Ji, C Bottecchia, F Lévesque, K Narsimhan, D Lehnherr, JP McMullen, ... The Journal of Organic Chemistry 87 (4), 2055-2062, 2021 | 29 | 2021 |
| Studies Toward the Scaling of Gas‐Liquid Photocycloadditions EB Corcoran, F Lévesque, JP McMullen, JR Naber ChemPhotoChem 2 (10), 931-937, 2018 | 26 | 2018 |
| Engineering Hydroxylase Activity, Selectivity, and Stability for a Scalable Concise Synthesis of a Key Intermediate to Belzutifan WL Cheung‐Lee, JN Kolev, JA McIntosh, AA Gil, W Pan, L Xiao, ... Angewandte Chemie International Edition 63 (13), e202316133, 2024 | 25 | 2024 |
| Effective control of crystal size via an integrated crystallization, wet milling, and annealing recirculation system W Meng, E Sirota, H Feng, JP McMullen, L Codan, AS Cote Organic Process Research & Development 24 (11), 2639-2650, 2020 | 24 | 2020 |
| Constrained version of the dynamic response surface methodology for modeling pharmaceutical reactions Y Dong, C Georgakis, J Mustakis, JM Hawkins, L Han, K Wang, ... Industrial & Engineering Chemistry Research 58 (30), 13611-13621, 2019 | 23 | 2019 |
| Development and scale-up of a continuous reaction for production of an active pharmaceutical ingredient intermediate JP McMullen, CH Marton, BD Sherry, G Spencer, J Kukura, NS Eyke Organic Process Research & Development 22 (9), 1208-1213, 2018 | 23 | 2018 |
| Manufacturing process development for belzutifan, part 6: ensuring scalability for a deoxyfluorination reaction M Pirnot, K Stone, TJ Wright, DJ Lamberto, J Schoell, Y Lam, K Zawatzky, ... Organic Process Research & Development 26 (3), 551-559, 2021 | 21 | 2021 |
