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Epithelial-mesenchymal transition in cancer: parallels between normal development and tumor progression DS Micalizzi, SM Farabaugh, HL Ford Journal of mammary gland biology and neoplasia 15, 117-134, 2010 | 1395 | 2010 |
A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancer J Lamb, S Ramaswamy, HL Ford, B Contreras, RV Martinez, FS Kittrell, ... Cell 114 (3), 323-334, 2003 | 495 | 2003 |
Drg-1 as a differentiation-related, putative metastatic suppressor gene in human colon cancer RJ Guan, HL Ford, Y Fu, Y Li, LM Shaw, AB Pardee Cancer research 60 (3), 749-755, 2000 | 461 | 2000 |
The miR-106b-25 cluster targets Smad7, activates TGF-β signaling, and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast cancer AL Smith, R Iwanaga, DJ Drasin, DS Micalizzi, RL Vartuli, AC Tan, ... Oncogene 31 (50), 5162-5171, 2012 | 369 | 2012 |
On the TRAIL to successful cancer therapy? Predicting and counteracting resistance against TRAIL-based therapeutics LY Dimberg, CK Anderson, R Camidge, K Behbakht, A Thorburn, HL Ford Oncogene 32 (11), 1341-1350, 2013 | 344 | 2013 |
The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-β signaling DS Micalizzi, KL Christensen, P Jedlicka, RD Coletta, AE Barón, ... The Journal of clinical investigation 119 (9), 2678-2690, 2009 | 286 | 2009 |
The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1 RD Coletta, K Christensen, KJ Reichenberger, J Lamb, D Micomonaco, ... Proceedings of the National Academy of Sciences 101 (17), 6478-6483, 2004 | 265 | 2004 |
Molecular pathways: targeting the TGF-β pathway for cancer therapy AL Smith, TP Robin, HL Ford Clinical Cancer Research 18 (17), 4514-4521, 2012 | 253 | 2012 |
Abrogation of the G2 cell cycle checkpoint associated with overexpression of HSIX1: A possible mechanism of breast carcinogenesis HL Ford, EN Kabingu, EA Bump, GL Mutter, AB Pardee Proceedings of the National Academy of Sciences 95 (21), 12608-12613, 1998 | 226 | 1998 |
Epithelial–mesenchymal transition and tumor suppression are controlled by a reciprocal feedback loop between ZEB1 and Grainyhead-like-2 B Cieply, J Farris, J Denvir, HL Ford, SM Frisch Cancer research 73 (20), 6299-6309, 2013 | 213 | 2013 |
Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition EL McCoy, R Iwanaga, P Jedlicka, NS Abbey, LA Chodosh, KA Heichman, ... The Journal of clinical investigation 119 (9), 2663-2677, 2009 | 212 | 2009 |
Six1 overexpression in ovarian carcinoma causes resistance to TRAIL-mediated apoptosis and is associated with poor survival K Behbakht, L Qamar, CS Aldridge, RD Coletta, SA Davidson, A Thorburn, ... Cancer research 67 (7), 3036-3042, 2007 | 206 | 2007 |
Breast cancer epithelial-to-mesenchymal transition: examining the functional consequences of plasticity DJ Drasin, TP Robin, HL Ford Breast Cancer Research 13, 1-13, 2011 | 205 | 2011 |
TRAIL receptor-targeted therapeutics: resistance mechanisms and strategies to avoid them A Thorburn, K Behbakht, H Ford Drug Resistance Updates 11 (1-2), 17-24, 2008 | 203 | 2008 |
Epithelial–mesenchymal transition in development and cancer DS Micalizzi, HL Ford Future oncology 5 (8), 1129-1143, 2009 | 183 | 2009 |
Structure-function analyses of the human SIX1–EYA2 complex reveal insights into metastasis and BOR syndrome AN Patrick, JH Cabrera, AL Smith, XS Chen, HL Ford, R Zhao Nature structural & molecular biology 20 (4), 447-453, 2013 | 172 | 2013 |
The six family of homeobox genes in development and cancer KL Christensen, AN Patrick, EL McCoy, HL Ford Advances in cancer research 101, 93-126, 2008 | 172 | 2008 |
EMT cells increase breast cancer metastasis via paracrine GLI activation in neighbouring tumour cells D Neelakantan, H Zhou, MUJ Oliphant, X Zhang, LM Simon, DM Henke, ... Nature communications 8 (1), 15773, 2017 | 170 | 2017 |
Eya2 is required to mediate the pro-metastatic functions of Six1 via the induction of TGF-β signaling, epithelial–mesenchymal transition, and cancer stem cell properties SM Farabaugh, DS Micalizzi, P Jedlicka, R Zhao, HL Ford Oncogene 31 (5), 552-562, 2012 | 161 | 2012 |