| Reactive astrocytes transduce inflammation in a blood-brain barrier model through a TNF-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin H Kim, K Leng, J Park, AG Sorets, S Kim, A Shostak, RJ Embalabala, ... Nature Communications 13 (1), 6581, 2022 | 106 | 2022 |
| Highly efficient neuronal gene knockout in vivo by CRISPR-Cas9 via neonatal intracerebroventricular injection of AAV in mice S Hana, M Peterson, H McLaughlin, E Marshall, AJ Fabian, O McKissick, ... Gene therapy 28 (10), 646-658, 2021 | 43 | 2021 |
| A microengineered Brain-Chip to model neuroinflammation in humans I Pediaditakis, KR Kodella, DV Manatakis, CY Le, S Barthakur, A Sorets, ... Iscience 25 (8), 2022 | 41 | 2022 |
| Caveolae-mediated transport at the injured blood–brain barrier as an underexplored pathway for central nervous system drug delivery AG Sorets, JC Rosch, CL Duvall, ES Lippmann Current opinion in chemical engineering 30, 86-95, 2020 | 19 | 2020 |
| Core polymer optimization of ternary siRNA nanoparticles enhances in vivo safety, pharmacokinetics, and tumor gene silencing SS Patel, EN Hoogenboezem, F Yu, CR DeJulius, RB Fletcher, AG Sorets, ... Biomaterials 297, 122098, 2023 | 14 | 2023 |
| Albumin-binding RNAi conjugate for carrier free treatment of arthritis JM Colazo, EN Hoogenboezem, MC Keech, N Francini, V Shah, F Yu, ... BioRxiv, 2023.05. 31.542971, 2023 | 9 | 2023 |
| Albumin-binding aptamer chimeras for improved siRNA bioavailability JC Rosch, EN Hoogenboezem, AG Sorets, CL Duvall, ES Lippmann Cellular and Molecular Bioengineering 15 (2), 161-173, 2022 | 9 | 2022 |
| LIPOPHILIC SIRNA CONJUGATES FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES CL Duvall, ES Lippmann, AG Sorets US Patent App. 18/737,720, 2024 | | 2024 |
| Fabrication of endothelialized capillary-like microchannel networks using sacrificial thermoresponsive microfibers JA Rector IV, L McBride, CM Weber, K Grossman, A Sorets, ... Biofabrication 17 (1), 015023, 2024 | | 2024 |
| Synthesis and characterization of chloroquine-modified albumin-binding siRNA-lipid conjugates for improved intracellular delivery and gene silencing in cancer cells JH Lo, EF Gbur, N Francini, J Ma, AG Sorets, RB Fletcher, F Yu, R D’Arcy, ... bioRxiv, 2024.10. 14.618042, 2024 | | 2024 |
| Lipid-siRNA conjugate accesses perivascular transport and achieves durable knockdown throughout the central nervous system AG Sorets, KR Schwensen, N Francini, A Kjar, AM Abdulrahman, ... bioRxiv, 2024 | | 2024 |
| IQGAP2 regulates blood-brain barrier immune dynamics KA Katdare, A Kjar, NM O’Brown, EH Neal, AG Sorets, A Shostak, ... iScience, 2023 | | 2023 |
