Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy G Luxán, JC Casanova, B Martínez-Poveda, B Prados, G D'amato, ... Nature medicine 19 (2), 193-201, 2013 | 376 | 2013 |
Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation L Luna-Zurita, B Prados, J Grego-Bessa, G Luxán, G Del Monte, ... The Journal of clinical investigation 120 (10), 3493-3507, 2010 | 282 | 2010 |
SARS-CoV-2 infects and induces cytotoxic effects in human cardiomyocytes D Bojkova, JUG Wagner, M Shumliakivska, GS Aslan, U Saleem, ... Cardiovascular research 116 (14), 2207-2215, 2020 | 267 | 2020 |
Endocardial notch signaling in cardiac development and disease G Luxán, G D’Amato, D MacGrogan, JL de la Pompa Circulation research 118 (1), e1-e18, 2016 | 262 | 2016 |
Single cell sequencing reveals endothelial plasticity with transient mesenchymal activation after myocardial infarction LS Tombor, D John, SF Glaser, G Luxán, E Forte, M Furtado, N Rosenthal, ... Nature communications 12 (1), 681, 2021 | 221 | 2021 |
Sequential Notch activation regulates ventricular chamber development G D’Amato, G Luxán, G del Monte-Nieto, B Martínez-Poveda, C Torroja, ... Nature cell biology 18 (1), 7-20, 2016 | 208 | 2016 |
Notch activation stimulates migration of breast cancer cells and promotes tumor growth V Bolós, E Mira, B Martínez-Poveda, G Luxán, M Cañamero, C Martínez-A, ... Breast Cancer Research 15 (4), 1-15, 2013 | 167 | 2013 |
Characterization of isolated ventricular myocytes from adult zebrafish (Danio rerio) F Brette, G Luxan, C Cros, H Dixey, C Wilson, HA Shiels Biochemical and biophysical research communications 374 (1), 143-146, 2008 | 129 | 2008 |
Sequential ligand-dependent notch signaling activation regulates valve primordium formation and morphogenesis D MacGrogan, G D’Amato, S Travisano, B Martinez-Poveda, G Luxán, ... Circulation research 118 (10), 1480-1497, 2016 | 126 | 2016 |
How to make a heart valve: from embryonic development to bioengineering of living valve substitutes D MacGrogan, G Luxán, A Driessen-Mol, C Bouten, F Baaijens, ... Cold Spring Harbor perspectives in medicine 4 (11), a013912, 2014 | 97 | 2014 |
Notch signalling in ventricular chamber development and cardiomyopathy G D'Amato, G Luxán, JL de la Pompa The FEBS journal 283 (23), 4223-4237, 2016 | 91 | 2016 |
Morphogenesis of myocardial trabeculae in the mouse embryo G Captur, R Wilson, MF Bennett, G Luxán, A Nasis, JL de la Pompa, ... Journal of anatomy 229 (2), 314-325, 2016 | 76 | 2016 |
Aging impairs the neurovascular interface in the heart JUG Wagner, LS Tombor, PF Malacarne, LM Kettenhausen, J Panthel, ... Science 381 (6660), 897-906, 2023 | 52 | 2023 |
Fibroblast‐mediated intercellular crosstalk in the healthy and diseased heart L Nicin, JUG Wagner, G Luxán, S Dimmeler FEBS letters 596 (5), 638-654, 2022 | 52 | 2022 |
Endothelial EphB4 maintains vascular integrity and transport function in adult heart G Luxán, J Stewen, N Díaz, K Kato, SK Maney, A Aravamudhan, ... elife 8, e45863, 2019 | 51 | 2019 |
Increased susceptibility of human endothelial cells to infections by SARS-CoV-2 variants JUG Wagner, D Bojkova, M Shumliakivska, G Luxán, L Nicin, GS Aslan, ... Basic Research in Cardiology 116 (1), 1-12, 2021 | 48 | 2021 |
The vasculature: a therapeutic target in heart failure? G Luxán, S Dimmeler Cardiovascular Research 118 (1), 53-64, 2022 | 41 | 2022 |
Myocardial Bmp2 gain causes ectopic EMT and promotes cardiomyocyte proliferation and immaturity B Prados, P Gómez-Apiñániz, T Papoutsi, G Luxán, S Zaffran, ... Cell death & disease 9 (3), 399, 2018 | 38 | 2018 |
Post-myocardial infarction heart failure dysregulates the bone vascular niche J Hoffmann, G Luxán, WT Abplanalp, SF Glaser, T Rasper, A Fischer, ... Nature Communications 12 (1), 3964, 2021 | 37 | 2021 |
DNMT3A clonal hematopoiesis-driver mutations induce cardiac fibrosis by paracrine activation of fibroblasts M Shumliakivska, G Luxán, I Hemmerling, M Scheller, X Li, ... Nature Communications 15 (1), 606, 2024 | 26 | 2024 |