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Nathan Skene
Nathan Skene
Lecturer ; UKRI Future Leaders Fellow ; UK DRI group leader at the UK Dementia Research Institute
E-mail confirmado em imperial.ac.uk - Página inicial
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Molecular architecture of the mouse nervous system
A Zeisel, H Hochgerner, P Lönnerberg, A Johnsson, F Memic, ...
Cell 174 (4), 999-1014. e22, 2018
24472018
Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk
IE Jansen, JE Savage, K Watanabe, J Bryois, DM Williams, S Steinberg, ...
Nature genetics 51 (3), 404-413, 2019
21992019
Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence
JE Savage, PR Jansen, S Stringer, K Watanabe, J Bryois, CA De Leeuw, ...
Nature genetics 50 (7), 912-919, 2018
12582018
Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways
PR Jansen, K Watanabe, S Stringer, N Skene, J Bryois, ...
Nature genetics 51 (3), 394-403, 2019
7972019
Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways
M Nagel, PR Jansen, S Stringer, K Watanabe, CA De Leeuw, J Bryois, ...
Nature genetics 50 (7), 920-927, 2018
7102018
Genetic identification of brain cell types underlying schizophrenia
NG Skene, J Bryois, TE Bakken, G Breen, JJ Crowley, HA Gaspar, ...
Nature genetics 50 (6), 825-833, 2018
6232018
Identification of Vulnerable Cell Types in Major Brain Disorders Using Single Cell Transcriptomes and Expression Weighted Cell Type Enrichment
N Skene, S Grant
Frontiers in Neuroscience, 2016
3262016
Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease
J Bryois, NG Skene, TF Hansen, LJA Kogelman, HJ Watson, Z Liu, ...
Nature genetics 52 (5), 482-493, 2020
2962020
Classes and continua of hippocampal CA1 inhibitory neurons revealed by single-cell transcriptomics
KD Harris, H Hochgerner, NG Skene, L Magno, L Katona, ...
PLoS biology 16 (6), e2006387, 2018
2892018
Single-nucleus RNA-seq is not suitable for detection of microglial activation genes in humans
N Thrupp, CS Frigerio, L Wolfs, NG Skene, N Fattorelli, S Poovathingal, ...
Cell reports 32 (13), 2020
2672020
Diversity of interneurons in the dorsal striatum revealed by single-cell RNA sequencing and PatchSeq
AB Muñoz-Manchado, CB Gonzales, A Zeisel, H Munguba, B Bekkouche, ...
Cell reports 24 (8), 2179-2190. e7, 2018
2252018
Probabilistic cell typing enables fine mapping of closely related cell types in situ
X Qian, KD Harris, T Hauling, D Nicoloutsopoulos, AB Muñoz-Manchado, ...
Nature methods 17 (1), 101-106, 2020
2222020
Architecture of the mouse brain synaptome
F Zhu, M Cizeron, Z Qiu, R Benavides-Piccione, MV Kopanitsa, NG Skene, ...
Neuron 99 (4), 781-799. e10, 2018
2212018
Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income
WD Hill, NM Davies, SJ Ritchie, NG Skene, J Bryois, S Bell, ...
Nature communications 10 (1), 5741, 2019
1882019
TNiK is required for postsynaptic and nuclear signaling pathways and cognitive function
MP Coba, NH Komiyama, J Nithianantharajah, MV Kopanitsa, ...
Journal of Neuroscience 32 (40), 13987-13999, 2012
1132012
Altered perivascular fibroblast activity precedes ALS disease onset
A Månberg, N Skene, F Sanders, M Trusohamn, J Remnestål, ...
Nature medicine 27 (4), 640-646, 2021
1012021
A genomic lifespan program that reorganises the young adult brain is targeted in schizophrenia
NG Skene, M Roy, SGN Grant
Elife 6, e17915, 2017
872017
Proteomic analysis of postsynaptic proteins in regions of the human neocortex
M Roy, O Sorokina, N Skene, C Simonnet, F Mazzo, R Zwart, E Sher, ...
Nature neuroscience 21 (1), 130-138, 2018
822018
MungeSumstats: a Bioconductor package for the standardization and quality control of many GWAS summary statistics
AE Murphy, BM Schilder, NG Skene
Bioinformatics 37 (23), 4593-4596, 2021
812021
Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals
JRI Coleman, J Bryois, HA Gaspar, PR Jansen, JE Savage, N Skene, ...
Molecular psychiatry 24 (2), 182-197, 2019
792019
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