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Daniel Scharf
Daniel Scharf
Postdoc Stanford
Email confirmado em stanford.edu
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Enzymatic carbon–sulfur bond formation in natural product biosynthesis
KL Dunbar, DH Scharf, A Litomska, C Hertweck
Chemical reviews 117 (8), 5521-5577, 2017
5362017
Biosynthesis and function of gliotoxin in Aspergillus fumigatus
DH Scharf, T Heinekamp, N Remme, P Hortschansky, AA Brakhage, ...
Applied microbiology and biotechnology 93, 467-472, 2012
2452012
Human and plant fungal pathogens: the role of secondary metabolites
DH Scharf, T Heinekamp, AA Brakhage
PLoS pathogens 10 (1), e1003859, 2014
1872014
Transannular Disulfide Formation in Gliotoxin Biosynthesis and Its Role in Self-Resistance of the Human Pathogen Aspergillus fumigatus
DH Scharf, N Remme, T Heinekamp, P Hortschansky, AA Brakhage, ...
Journal of the American Chemical Society 132 (29), 10136-10141, 2010
1692010
Gliotoxin–bane or boon?
DH Scharf, AA Brakhage, PK Mukherjee
Environmental Microbiology 18 (4), 1096-1109, 2016
1392016
A Dedicated Glutathione S-Transferase Mediates Carbon–Sulfur Bond Formation in Gliotoxin Biosynthesis
DH Scharf, N Remme, A Habel, P Chankhamjon, K Scherlach, ...
Journal of the American Chemical Society 133 (32), 12322-12325, 2011
1332011
Anion receptors based on halogen bonding with halo-1, 2, 3-triazoliums
R Tepper, B Schulze, M Jäger, C Friebe, DH Scharf, H Görls, ...
The Journal of organic chemistry 80 (6), 3139-3150, 2015
1172015
The CCAAT-binding complex coordinates the oxidative stress response in eukaryotes
M Thön, Q Al Abdallah, P Hortschansky, DH Scharf, M Eisendle, H Haas, ...
Nucleic acids research 38 (4), 1098-1113, 2010
1142010
Opposed Effects of Enzymatic Gliotoxin N- and S-Methylations
DH Scharf, A Habel, T Heinekamp, AA Brakhage, C Hertweck
Journal of the American Chemical Society 136 (33), 11674-11679, 2014
1042014
Aspects on evolution of fungal β-lactam biosynthesis gene clusters and recruitment of trans-acting factors
AA Brakhage, M Thön, P Spröte, DH Scharf, Q Al-Abdallah, SM Wolke, ...
Phytochemistry 70 (15-16), 1801-1811, 2009
1022009
Identification of immunogenic antigens from Aspergillus fumigatus by direct multiparameter characterization of specific conventional and regulatory CD4+ T cells
P Bacher, O Kniemeyer, J Teutschbein, M Thön, M Vödisch, ...
The Journal of Immunology 193 (7), 3332-3343, 2014
842014
Epidithiol formation by an unprecedented twin carbon–sulfur lyase in the gliotoxin pathway
DH Scharf, P Chankhamjon, K Scherlach, T Heinekamp, M Roth, ...
Angewandte Chemie International Edition 51 (40), 10064-10068, 2012
702012
Epidithiodiketopiperazine biosynthesis: A four‐enzyme cascade converts glutathione conjugates into transannular disulfide bridges
DH Scharf, P Chankhamjon, K Scherlach, T Heinekamp, K Willing, ...
Angewandte Chemie International Edition 52 (42), 11092-11095, 2013
662013
DNA minor groove sensing and widening by the CCAAT-binding complex
EM Huber, DH Scharf, P Hortschansky, M Groll, AA Brakhage
Structure 20 (10), 1757-1768, 2012
622012
Flavoenzyme‐catalyzed formation of disulfide bonds in natural products
DH Scharf, M Groll, A Habel, T Heinekamp, C Hertweck, AA Brakhage, ...
Angewandte Chemie International Edition 53 (8), 2221-2224, 2014
562014
Star-shaped drug carriers for doxorubicin with POEGMA and POEtOxMA brush-like shells: a structural, physical, and biological comparison
K Knop, D Pretzel, A Urbanek, T Rudolph, DH Scharf, A Schallon, ...
Biomacromolecules 14 (8), 2536-2548, 2013
452013
Identification of the novel penicillin biosynthesis gene aatB of Aspergillus nidulans and its putative evolutionary relationship to this fungal secondary metabolism …
P Spröte, MJ Hynes, P Hortschansky, E Shelest, DH Scharf, SM Wolke, ...
Molecular microbiology 70 (2), 445-461, 2008
452008
Engineering fungal secondary metabolism: a roadmap to novel compounds
DH Scharf, AA Brakhage
Journal of biotechnology 163 (2), 179-183, 2013
432013
Structural insights into ligand recognition and activation of the melanocortin-4 receptor
H Zhang, LN Chen, D Yang, C Mao, Q Shen, W Feng, DD Shen, A Dai, ...
Cell Research 31 (11), 1163-1175, 2021
412021
Amphiphilic star-shaped block copolymers as unimolecular drug delivery systems: investigations using a novel fungicide
K Knop, GM Pavlov, T Rudolph, K Martin, D Pretzel, BO Jahn, DH Scharf, ...
Soft Matter 9 (3), 715-726, 2013
402013
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