Sebastian Hiller

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Gerhard WagnerHarvard Medical SchoolEmail confirmado em hms.harvard.edu
Björn M. BurmannProfessor, Department of Chemistry & Molecular Biology, Wallenberg Centre (WCMTM)Email confirmado em gu.se
Petr BrozFull Professor, Department of Biochemistry, University of LausanneEmail confirmado em unil.ch
Timm MaierBiozentrum, University of BaselEmail confirmado em unibas.ch
Daniel J MullerETH Zurich, Department of Biosystems Science and EngineeringEmail confirmado em bsse.ethz.ch
Roman P. JakobUniversity of Basel,Email confirmado em unibas.ch
Henning StahlbergProfessor for Physics, EPFL, SwitzerlandEmail confirmado em epfl.ch
Urs JenalBiozentrum - University of BaselEmail confirmado em unibas.ch
Sebastian RühlSenior Researcher at T3 Pharmaceuticals AGEmail confirmado em stjude.org
Rosalie HeiligBeatson Institute for Cancer ResearchEmail confirmado em glasgow.ac.uk
Vladislav Y OrekhovDepartment of Chemistry and Molecular Biology, University of GothenburgEmail confirmado em nmr.gu.se
Badri N DubeyStaff Scientist, Centre for Structural Systems Biology (CSSB) Deutsches Elektronen-SynchrotronEmail confirmado em desy.de
Tim SharpeUniversity of BaselEmail confirmado em unibas.ch
Elia AgustoniUniversity of BaselEmail confirmado em unibas.ch
Kim LewisUniversity Distinguished Professor, Northeastern UniversityEmail confirmado em neu.edu
Guillaume MasBiozentrum - University BaselEmail confirmado em unibas.ch
Peter BondBII A*STAREmail confirmado em bii.a-star.edu.sg
Parthasarathi RathSenior Scientist, R&D Discovery Sciences, AstraZeneca-SwedenEmail confirmado em astrazeneca.com
Seyed Majed ModaresiPostdoctoral researcher, MIT, Broad Institute of MIT & HarvardEmail confirmado em mit.edu
Lichun HeProf. Innovation Academy for Precision Measurement Science and Technology, CASEmail confirmado em apm.ac.cn

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Sebastian Hiller

Professor for Structural Biology and Biophysics, Biozentrum, University Basel, Switzerland

Email confirmado em unibas.ch

Structural Biology NMR Spectroscopy


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GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death L Sborgi, S Rühl, E Mulvihill, J Pipercevic, R Heilig, H Stahlberg, ... The EMBO Journal 35 (16), 1766-1778, 2016	1117	2016
Solution structure of the integral human membrane protein VDAC-1 in detergent micelles S Hiller, RG Garces, TJ Malia, VY Orekhov, M Colombini, G Wagner Science 321 (5893), 1206-1210, 2008	768	2008
A new antibiotic selectively kills Gram-negative pathogens Y Imai, KJ Meyer, A Iinishi, Q Favre-Godal, R Green, S Manuse, M Caboni, ... Nature 576 (7787), 459-464, 2019	682	2019
Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation FL Zhong, O Mamaï, L Sborgi, L Boussofara, R Hopkins, K Robinson, ... Cell 167 (1), 187-202. e17, 2016	428	2016
ASC filament formation serves as a signal amplification mechanism for inflammasomes MS Dick, L Sborgi, S Rühl, S Hiller, P Broz Nature communications 7 (1), 11929, 2016	397	2016
The Gasdermin‐D pore acts as a conduit for IL‐1β secretion in mice R Heilig, MS Dick, L Sborgi, E Meunier, S Hiller, P Broz European journal of immunology 48 (4), 584-592, 2018	390	2018
Chimeric peptidomimetic antibiotics against Gram-negative bacteria A Luther, M Urfer, M Zahn, M Müller, SY Wang, M Mondal, A Vitale, ... Nature 576 (7787), 452-458, 2019	293	2019
Automated projection spectroscopy (APSY) S Hiller, F Fiorito, K Wüthrich, G Wider Proceedings of the National Academy of Sciences of the United States of …, 2005	281	2005
Mechanism of membrane pore formation by human gasdermin‐D E Mulvihill, L Sborgi, SA Mari, M Pfreundschuh, S Hiller, DJ Müller The EMBO journal 37 (14), e98321, 2018	265	2018
Regulation of α-synuclein by chaperones in mammalian cells BM Burmann, JA Gerez, I Matečko-Burmann, S Campioni, P Kumari, ... Nature 577 (7788), 127-132, 2020	247	2020
PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains C Suzuki, RG Garces, KA Edmonds, S Hiller, SG Hyberts, A Marintchev, ... Proceedings of the National Academy of Sciences 105 (9), 3274-3279, 2008	215	2008
Structural and functional characterization of the integral membrane protein VDAC-1 in lipid bilayer nanodiscs T Raschle, S Hiller, TY Yu, AJ Rice, T Walz, G Wagner Journal of the American Chemical Society 131 (49), 17777-17779, 2009	208	2009
Cyclic di-GMP acts as a cell cycle oscillator to drive chromosome replication C Lori, S Ozaki, S Steiner, R Böhm, S Abel, BN Dubey, T Schirmer, ... Nature 523 (7559), 236-239, 2015	205	2015
A Proton‐Detected 4D Solid‐State NMR Experiment for Protein Structure Determination M Huber, S Hiller, P Schanda, M Ernst, A Böckmann, R Verel, BH Meier ChemPhysChem 12 (5), 915-918, 2011	190	2011
The antibiotic darobactin mimics a β-strand to inhibit outer membrane insertase H Kaur, RP Jakob, JK Marzinek, R Green, Y Imai, JR Bolla, E Agustoni, ... Nature 593 (7857), 125-129, 2021	184	2021
Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy L Sborgi, F Ravotti, VP Dandey, MS Dick, A Mazur, S Reckel, M Chami, ... Proceedings of the National Academy of Sciences 112 (43), 13237-13242, 2015	178	2015
Inositol pyrophosphates promote the interaction of SPX domains with the coiled-coil motif of PHR transcription factors to regulate plant phosphate homeostasis MK Ried, R Wild, J Zhu, J Pipercevic, K Sturm, L Broger, RK Harmel, ... Nature communications 12 (1), 384, 2021	163	2021
HP1(Swi6) Mediates the Recognition and Destruction of Heterochromatic RNA Transcripts C Keller, R Adaixo, R Stunnenberg, KJ Woolcock, S Hiller, M Bühler Molecular Cell, 2012	161	2012
NMR structure of the apoptosis-and inflammation-related NALP1 pyrin domain S Hiller, A Kohl, F Fiorito, T Herrmann, G Wider, J Tschopp, MG Grütter, ... Structure 11 (10), 1199-1205, 2003	160	2003
Conformation and dynamics of the periplasmic membrane-protein–chaperone complexes OmpX–Skp and tOmpA–Skp BM Burmann, C Wang, S Hiller Nature Structural and Molecular Biology 20 (11), 1265, 2013	154	2013

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