| Dysbiosis contributes to arthritis development via activation of autoreactive T cells in the intestine Y Maeda, T Kurakawa, E Umemoto, D Motooka, Y Ito, K Gotoh, K Hirota, ... Arthritis & rheumatology 68 (11), 2646-2661, 2016 | 669 | 2016 |
| Oral pathobiont induces systemic inflammation and metabolic changes associated with alteration of gut microbiota K Arimatsu, H Yamada, H Miyazawa, T Minagawa, M Nakajima, MI Ryder, ... Scientific reports 4 (1), 4828, 2014 | 596 | 2014 |
| Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment Y Kitagawa, N Ohkura, Y Kidani, A Vandenbon, K Hirota, R Kawakami, ... Nature immunology 18 (2), 173-183, 2017 | 378 | 2017 |
| Metagenome-wide association study of gut microbiome revealed novel aetiology of rheumatoid arthritis in the Japanese population T Kishikawa, Y Maeda, T Nii, D Motooka, Y Matsumoto, M Matsushita, ... Annals of the rheumatic diseases 79 (1), 103-111, 2020 | 233 | 2020 |
| Lypd8 promotes the segregation of flagellated microbiota and colonic epithelia R Okumura, T Kurakawa, T Nakano, H Kayama, M Kinoshita, D Motooka, ... Nature 532 (7597), 117-121, 2016 | 226 | 2016 |
| Metagenomic analysis reveals dynamic changes of whole gut microbiota in the acute phase of intensive care unit patients M Ojima, D Motooka, K Shimizu, K Gotoh, A Shintani, K Yoshiya, ... Digestive diseases and sciences 61, 1628-1634, 2016 | 220 | 2016 |
| Generation of colonic IgA-secreting cells in the caecal patch K Masahata, E Umemoto, H Kayama, M Kotani, S Nakamura, T Kurakawa, ... Nature communications 5 (1), 3704, 2014 | 203 | 2014 |
| Distinct methylation levels of mature microRNAs in gastrointestinal cancers M Konno, J Koseki, A Asai, A Yamagata, T Shimamura, D Motooka, ... Nature communications 10 (1), 3888, 2019 | 167 | 2019 |
| Gut microbiota–derived short-chain fatty acids promote prostate cancer growth via IGF1 signaling M Matsushita, K Fujita, T Hayashi, H Kayama, D Motooka, H Hase, ... Cancer research 81 (15), 4014-4026, 2021 | 136 | 2021 |
| CCR8-targeted specific depletion of clonally expanded Treg cells in tumor tissues evokes potent tumor immunity with long-lasting memory Y Kidani, W Nogami, Y Yasumizu, A Kawashima, A Tanaka, Y Sonoda, ... Proceedings of the National Academy of Sciences 119 (7), e2114282119, 2022 | 132 | 2022 |
| Performance comparison of second-and third-generation sequencers using a bacterial genome with two chromosomes M Miyamoto, D Motooka, K Gotoh, T Imai, K Yoshitake, N Goto, T Iida, ... BMC genomics 15, 1-9, 2014 | 126 | 2014 |
| Engineered ACE2 receptor therapy overcomes mutational escape of SARS-CoV-2 Y Higuchi, T Suzuki, T Arimori, N Ikemura, E Mihara, Y Kirita, E Ohgitani, ... Nature communications 12 (1), 3802, 2021 | 123 | 2021 |
| Indigo Naturalis ameliorates murine dextran sodium sulfate-induced colitis via aryl hydrocarbon receptor activation S Kawai, H Iijima, S Shinzaki, S Hiyama, T Yamaguchi, M Araki, S Iwatani, ... Journal of gastroenterology 52, 904-919, 2017 | 115 | 2017 |
| Post-Golgi anterograde transport requires GARP-dependent endosome-to-TGN retrograde transport T Hirata, M Fujita, S Nakamura, K Gotoh, D Motooka, Y Murakami, ... Molecular biology of the cell 26 (17), 3071-3084, 2015 | 108 | 2015 |
| Transcriptomics identify thrombospondin‐2 as a biomarker for NASH and advanced liver fibrosis K Kozumi, T Kodama, H Murai, S Sakane, O Govaere, S Cockell, ... Hepatology 74 (5), 2452-2466, 2021 | 107 | 2021 |
| Genome-wide screening uncovers the significance of N-sulfation of heparan sulfate as a host cell factor for chikungunya virus infection A Tanaka, U Tumkosit, S Nakamura, D Motooka, N Kishishita, ... Journal of virology 91 (13), 10.1128/jvi. 00432-17, 2017 | 105 | 2017 |
| Comprehensive subspecies identification of 175 nontuberculous mycobacteria species based on 7547 genomic profiles Y Matsumoto, T Kinjo, D Motooka, D Nabeya, N Jung, K Uechi, T Horii, ... Emerging microbes & infections 8 (1), 1043-1053, 2019 | 102 | 2019 |
| Multiomics identifies the link between intratumor steatosis and the exhausted tumor immune microenvironment in hepatocellular carcinoma H Murai, T Kodama, K Maesaka, S Tange, D Motooka, Y Suzuki, ... Hepatology 77 (1), 77-91, 2023 | 101 | 2023 |
| Regulatory T cell-specific epigenomic region variants are a key determinant of susceptibility to common autoimmune diseases N Ohkura, Y Yasumizu, Y Kitagawa, A Tanaka, Y Nakamura, D Motooka, ... Immunity 52 (6), 1119-1132. e4, 2020 | 100 | 2020 |
| Benchmark of 16S rRNA gene amplicon sequencing using Japanese gut microbiome data from the V1–V2 and V3–V4 primer sets S Kameoka, D Motooka, S Watanabe, R Kubo, N Jung, Y Midorikawa, ... BMC genomics 22 (1), 527, 2021 | 86 | 2021 |
