| Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists H Kanzler, FJ Barrat, EM Hessel, RL Coffman Nature medicine 13 (5), 552-559, 2007 | 1131 | 2007 |
| Functions of T cells in asthma: more than just TH2 cells CM Lloyd, EM Hessel Nature reviews immunology 10 (12), 838-848, 2010 | 771 | 2010 |
| PI3K inhibitors in inflammation, autoimmunity and cancer AK Stark, S Sriskantharajah, EM Hessel, K Okkenhaug Current opinion in pharmacology 23, 82-91, 2015 | 340 | 2015 |
| Membrane-bound TNF supports secondary lymphoid organ structure but is subservient to secreted TNF in driving autoimmune inflammation SR Ruuls, RM Hoek, VN Ngo, T McNeil, LA Lucian, MJ Janatpour, ... Immunity 15 (4), 533-543, 2001 | 323 | 2001 |
| Influenza-induced monocyte-derived alveolar macrophages confer prolonged antibacterial protection H Aegerter, J Kulikauskaite, S Crotta, H Patel, G Kelly, EM Hessel, ... Nature Immunology 21 (2), 145-157, 2020 | 310 | 2020 |
| Lung inflammation and epithelial changes in a murine model of atopic asthma. DI Blyth, MS Pedrick, TJ Savage, EM Hessel, D Fattah American journal of respiratory cell and molecular biology 14 (5), 425-438, 1996 | 289 | 1996 |
| IFNλ is a potent anti‐influenza therapeutic without the inflammatory side effects of IFNα treatment S Davidson, TM McCabe, S Crotta, HH Gad, EM Hessel, S Beinke, ... EMBO Molecular Medicine 8 (9), 1099-1112, 2016 | 272 | 2016 |
| A restricted subset of dendritic cells captures airborne antigens and remains able to activate specific T cells long after antigen exposure V Julia, EM Hessel, L Malherbe, N Glaichenhaus, A O'Garra, RL Coffman Immunity 16 (2), 271-283, 2002 | 269 | 2002 |
| Development of airway hyperresponsiveness is dependent on interferon-gamma and independent of eosinophil infiltration. EM Hessel, AJ Van Oosterhout, I Van Ark, B Van Esch, G Hofman, ... American journal of respiratory cell and molecular biology 16 (3), 325-334, 1997 | 257 | 1997 |
| Obesity and disease severity magnify disturbed microbiome-immune interactions in asthma patients D Michalovich, N Rodriguez-Perez, S Smolinska, M Pirozynski, ... Nature communications 10 (1), 1-14, 2019 | 207 | 2019 |
| Combination immunotherapy with a CpG oligonucleotide (1018 ISS) and rituximab in patients with non-Hodgkin lymphoma: Increased JW Friedberg, H Kim, M McCauley, EM Hessel, P Sims, DC Fisher, ... Blood 105 (2), 489-495, 2005 | 197 | 2005 |
| Immunostimulatory sequences regulate interferon-inducible genes but not allergic airway responses GM Gauvreau, EM Hessel, LP Boulet, RL Coffman, PM O'Byrne American journal of respiratory and critical care medicine 174 (1), 15-20, 2006 | 167 | 2006 |
| Immunostimulatory oligonucleotides block allergic airway inflammation by inhibiting Th2 cell activation and IgE-mediated cytokine induction EM Hessel, M Chu, JO Lizcano, B Chang, N Herman, SA Kell, ... Journal of Experimental Medicine 202 (11), 1563-1573, 2005 | 154 | 2005 |
| Histamine-secreting microbes are increased in the gut of adult asthma patients W Barcik, B Pugin, P Westermann, NR Perez, R Ferstl, M Wawrzyniak, ... Journal of Allergy and Clinical Immunology 138 (5), 1491-1494. e7, 2016 | 153 | 2016 |
| CX3CR1 is required for airway inflammation by promoting T helper cell survival and maintenance in inflamed lung C Mionnet, V Buatois, A Kanda, V Milcent, S Fleury, D Lair, M Langelot, ... Nature medicine 16 (11), 1305-1312, 2010 | 150 | 2010 |
| Acute respiratory distress syndrome neutrophils have a distinct phenotype and are resistant to phosphoinositide 3-kinase inhibition JK Juss, D House, A Amour, M Begg, J Herre, DML Storisteanu, ... American journal of respiratory and critical care medicine 194 (8), 961-973, 2016 | 149 | 2016 |
| Bronchoconstriction and airway hyperresponsiveness after ovalbumin inhalation in sensitized mice EM Hessel, AJM Van Oosterhout, CL Hofstra, JJ De Bie, J Garssen, ... European Journal of Pharmacology: Environmental Toxicology and Pharmacology …, 1995 | 145 | 1995 |
| Airway host-microbiome interactions in chronic obstructive pulmonary disease Z Wang, B Maschera, S Lea, U Kolsum, D Michalovich, S Van Horn, ... Respiratory research 20, 1-14, 2019 | 137 | 2019 |
| Murine CTLA4-IgG treatment inhibits airway eosinophilia and hyperresponsiveness and attenuates IgE upregulation in a murine model of allergic asthma AJM Van Oosterhout, CL Hofstra, R Shields, B Chan, I Van Ark, ... American journal of respiratory cell and molecular biology 17 (3), 386-392, 1997 | 137 | 1997 |
| Characterization of chemokines and chemokine receptors in two murine models of inflammatory bowel disease: IL‐10–/–mice and Rag‐2–/–mice reconstituted with CD4+ CD45RBhigh T cells H Scheerens, E Hessel, R de Waal‐Malefyt, MW Leach, D Rennick European journal of immunology 31 (5), 1465-1474, 2001 | 136 | 2001 |
