| Small-molecule–induced DNA damage identifies alternative DNA structures in human genes R Rodriguez, KM Miller, JV Forment, CR Bradshaw, M Nikan, S Britton, ... Nature chemical biology 8 (3), 301-310, 2012 | 756 | 2012 |
| Salinomycin kills cancer stem cells by sequestering iron in lysosomes TT Mai, A Hamaï, A Hienzsch, T Cañeque, S Müller, J Wicinski, O Cabaud, ... Nature chemistry 9 (10), 1025-1033, 2017 | 541 | 2017 |
| A novel small molecule that alters shelterin integrity and triggers a DNA-damage response at telomeres R Rodriguez, S Müller, JA Yeoman, C Trentesaux, JF Riou, ... Journal of the American Chemical Society 130 (47), 15758-15759, 2008 | 519 | 2008 |
| Chemical inhibition of NAT10 corrects defects of laminopathic cells D Larrieu, S Britton, M Demir, R Rodriguez, SP Jackson Science 344 (6183), 527-532, 2014 | 356 | 2014 |
| Trisubstituted isoalloxazines as a new class of G-quadruplex binding ligands: small molecule regulation of c-kit oncogene expression M Bejugam, S Sewitz, PS Shirude, R Rodriguez, R Shahid, ... Journal of the American Chemical Society 129 (43), 12926-12927, 2007 | 308 | 2007 |
| The transcription factor FOXM1 is a cellular target of the natural product thiostrepton NS Hegde, DA Sanders, R Rodriguez, S Balasubramanian Nature chemistry 3 (9), 725-731, 2011 | 307 | 2011 |
| PML-regulated mitochondrial metabolism enhances chemosensitivity in human ovarian cancers G Gentric, Y Kieffer, V Mieulet, O Goundiam, C Bonneau, F Nemati, ... Cell metabolism 29 (1), 156-173. e10, 2019 | 252 | 2019 |
| A single-molecule platform for investigation of interactions between G-quadruplexes and small-molecule ligands D Koirala, S Dhakal, B Ashbridge, Y Sannohe, R Rodriguez, H Sugiyama, ... Nature chemistry 3 (10), 782-787, 2011 | 245 | 2011 |
| Small-molecule-mediated G-quadruplex isolation from human cells S Müller, S Kumari, R Rodriguez, S Balasubramanian Nature chemistry 2 (12), 1095-1098, 2010 | 228 | 2010 |
| CD44 regulates epigenetic plasticity by mediating iron endocytosis S Müller, F Sindikubwabo, T Cañeque, A Lafon, A Versini, B Lombard, ... Nature chemistry 12 (10), 929-938, 2020 | 197 | 2020 |
| Selective RNAVersus DNA G-Quadruplex Targeting by In Situ Click Chemistry M Di Antonio, G Biffi, A Mariani, EA Raiber, R Rodriguez, ... Angewandte Chemie (International ed. in English) 51 (44), 11073, 2012 | 193 | 2012 |
| G-Quadruplex-Binding Benzo[a]phenoxazines Down-Regulate c-KIT Expression in Human Gastric Carcinoma Cells KIE McLuckie, ZAE Waller, DA Sanders, D Alves, R Rodriguez, J Dash, ... Journal of the American Chemical Society 133 (8), 2658-2663, 2011 | 186 | 2011 |
| Visualizing biologically active small molecules in cells using click chemistry T Cañeque, S Müller, R Rodriguez Nature Reviews Chemistry 2 (9), 202-215, 2018 | 174 | 2018 |
| Persister cancer cells: Iron addiction and vulnerability to ferroptosis R Rodriguez, SL Schreiber, M Conrad Molecular cell 82 (4), 728-740, 2022 | 166 | 2022 |
| Chemistry and biology of ferritin M Plays, S Müller, R Rodriguez Metallomics 13 (5), mfab021, 2021 | 165 | 2021 |
| Pyridostatin analogues promote telomere dysfunction and long-term growth inhibition in human cancer cells S Müller, DA Sanders, M Di Antonio, S Matsis, JF Riou, R Rodriguez, ... Organic & biomolecular chemistry 10 (32), 6537-6546, 2012 | 162 | 2012 |
| Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome G Balmus, D Larrieu, AC Barros, C Collins, M Abrudan, M Demir, ... Nature communications 9 (1), 1700, 2018 | 156 | 2018 |
| Oxazole-based peptide macrocycles: a new class of G-quadruplex binding ligands K Jantos, R Rodriguez, S Ladame, PS Shirude, S Balasubramanian Journal of the American Chemical Society 128 (42), 13662-13663, 2006 | 147 | 2006 |
| Ligand-driven G-quadruplex conformational switching by using an unusual mode of interaction R Rodriguez, GD Pantoş, DPN Gonçalves, JKM Sanders, ... Angewandte Chemie (International ed. in English) 46 (28), 5405, 2007 | 143 | 2007 |
| Click chemistry enables preclinical evaluation of targeted epigenetic therapies DS Tyler, J Vappiani, T Cañeque, EYN Lam, A Ward, O Gilan, YC Chan, ... Science 356 (6345), 1397-1401, 2017 | 142 | 2017 |
Shankar BalasubramanianUniversity of CambridgeAdresă de e-mail confirmată pe cam.ac.uk
