| Single-cell bioluminescence imaging of deep tissue in freely moving animals S Iwano, M Sugiyama, H Hama, A Watakabe, N Hasegawa, T Kuchimaru, ... Science 359 (6378), 935-939, 2018 | 455 | 2018 |
| A luciferin analogue generating near-infrared bioluminescence achieves highly sensitive deep-tissue imaging T Kuchimaru, S Iwano, M Kiyama, S Mitsumata, T Kadonosono, H Niwa, ... Nature communications 7 (1), 11856, 2016 | 250 | 2016 |
| Development of simple firefly luciferin analogs emitting blue, green, red, and near-infrared biological window light S Iwano, R Obata, C Miura, M Kiyama, K Hama, M Nakamura, Y Amano, ... Tetrahedron 69 (19), 3847-3856, 2013 | 139 | 2013 |
| Synthesis and luminescence properties of biphenyl-type firefly luciferin analogs with a new, near-infrared light-emitting bioluminophore C Miura, M Kiyama, S Iwano, K Ito, R Obata, T Hirano, S Maki, H Niwa Tetrahedron 69 (46), 9726-9734, 2013 | 46 | 2013 |
| Functional visualization of NK cell-mediated killing of metastatic single tumor cells H Ichise, S Tsukamoto, T Hirashima, Y Konishi, C Oki, S Tsukiji, S Iwano, ... Elife 11, e76269, 2022 | 42 | 2022 |
| Synthesis of firefly luciferin analogues and evaluation of the luminescent properties S Ioka, T Saitoh, S Iwano, K Suzuki, SA Maki, A Miyawaki, M Imoto, ... Chemistry–A European Journal 22 (27), 9330-9337, 2016 | 34 | 2016 |
| Quantum yield improvement of red-light-emitting firefly luciferin analogues for in vivo bioluminescence imaging M Kiyama, S Iwano, S Otsuka, SW Lu, R Obata, A Miyawaki, T Hirano, ... Tetrahedron 74 (6), 652-660, 2018 | 33 | 2018 |
| Synthesis and Luminescence Properties of Near-Infrared N-Heterocyclic Luciferin Analogues for In Vivo Optical Imaging R Saito, T Kuchimaru, S Higashi, SW Lu, M Kiyama, S Iwano, R Obata, ... Bulletin of the Chemical Society of Japan 92 (3), 608-618, 2019 | 29 | 2019 |
| Spectroscopic studies of the color modulation mechanism of firefly (beetle) bioluminescence with amino-analogs of luciferin and oxyluciferin T Hirano, H Nagai, T Matsuhashi, Y Hasumi, S Iwano, K Ito, S Maki, ... Photochemical & Photobiological Sciences 11, 1281-1284, 2012 | 25 | 2012 |
| Toward bioluminescence in the near-infrared region: Tuning the emission wavelength of firefly luciferin analogues by allyl substitution N Kitada, T Saitoh, Y Ikeda, S Iwano, R Obata, H Niwa, T Hirano, ... Tetrahedron Letters 59 (12), 1087-1090, 2018 | 24 | 2018 |
| DHODH inhibition synergizes with DNA-demethylating agents in the treatment of myelodysplastic syndromes K Kayamori, Y Nagai, C Zhong, S Kaito, D Shinoda, S Koide, ... Blood advances 5 (2), 438-450, 2021 | 23 | 2021 |
| Multicolor bioluminescence obtained using firefly luciferin M Kiyama, R Saito, S Iwano, R Obata, H Niwa, S A Maki Current Topics in Medicinal Chemistry 16 (24), 2648-2655, 2016 | 17 | 2016 |
| Development of near‐infrared firefly luciferin analogue reacted with wild‐type and mutant luciferases N Kitada, R Saito, R Obata, S Iwano, K Karube, A Miyawaki, T Hirano, ... Chirality 32 (7), 922-931, 2020 | 16 | 2020 |
| A non-invasive system to monitor in vivo neural graft activity after spinal cord injury K Ago, N Nagoshi, K Imaizumi, T Kitagawa, M Kawai, K Kajikawa, ... Communications biology 5 (1), 803, 2022 | 13* | 2022 |
| Development of phenyl oligoene-type firefly luciferin analogues with extended π-electronic conjugation for near-infrared bioluminescence G Kamiya, N Kitada, R Saito-Moriya, R Obata, S Iwano, A Miyawaki, ... Chemistry Letters 50 (8), 1523-1525, 2021 | 8 | 2021 |
| Efficacy of the novel tubulin polymerization inhibitor PTC‐028 for myelodysplastic syndrome C Zhong, K Kayamori, S Koide, D Shinoda, M Oshima, ... Cancer Science 111 (12), 4336-4347, 2020 | 7 | 2020 |
| Development of two mouse strains conditionally expressing bright luciferases with distinct emission spectra as new tools for in vivo imaging T Nakashiba, K Ogoh, S Iwano, T Sugiyama, S Mizuno-Iijima, ... Lab Animal 52 (10), 247-257, 2023 | 6 | 2023 |
| Secretory GFP reconstitution labeling of neighboring cells interrogates cell–cell interactions in metastatic niches M Minegishi, T Kuchimaru, K Nishikawa, T Isagawa, S Iwano, K Iida, ... Nature communications 14 (1), 8031, 2023 | 4 | 2023 |
| Akaluc bioluminescence offers superior sensitivity to track in vivo dynamics of SARS-CoV-2 infection T Tamura, H Ito, S Torii, L Wang, R Suzuki, S Tsujino, A Kamiyama, Y Oda, ... Iscience 27 (5), 2024 | 3 | 2024 |
| Metastatic Single Tumor Cells Evade NK Cell-mediated Killing by Thrombin-mediated Loss of the Activating Ligand CD155/PVR/Necl-5 H Ichise, S Tsukamoto, T Hirashima, Y Konishi, C Oki, S Tsukiji, S Iwano, ... bioRxiv, 2021.01. 15.426784, 2021 | 1 | 2021 |