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Mean Ghim
Mean Ghim
Associate Research Scientist at Yale School of Medicine
Adresă de e-mail confirmată pe yale.edu
Titlu
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Understanding mechanobiology in cultured endothelium: A review of the orbital shaker method
CM Warboys, M Ghim, PD Weinberg
Atherosclerosis 285, 170-177, 2019
792019
Visualization of three pathways for macromolecule transport across cultured endothelium and their modification by flow
M Ghim, P Alpresa, SW Yang, ST Braakman, SG Gray, SJ Sherwin, ...
American Journal of Physiology-Heart and Circulatory Physiology 313 (5 …, 2017
562017
A novel method for segmenting growth of cells in sheared endothelial culture reveals the secretion of an anti-inflammatory mediator
M Ghim, KT Pang, M Arshad, X Wang, PD Weinberg
Journal of biological engineering 12, 1-13, 2018
412018
Endothelial cells exposed to atheroprotective flow secrete follistatin-like 1 protein which reduces transcytosis and inflammation
M Ghim, KT Pang, SA Burnap, F Baig, X Yin, M Arshad, M Mayr, ...
Atherosclerosis 333, 56-66, 2021
222021
Homeostatic, non-canonical role of macrophage elastase in vascular integrity
M Salarian, M Ghim, J Toczek, J Han, D Weiss, B Spronck, ...
Circulation research 132 (4), 432-448, 2023
172023
Leucine-rich α-2-glycoprotein 1 suppresses endothelial cell activation through ADAM10-mediated shedding of TNF-α receptor
KT Pang, M Ghim, C Liu, HM Tay, CW Fhu, RN Chia, B Qiu, ...
Frontiers in Cell and Developmental Biology 9, 706143, 2021
162021
The role of tricellular junctions in the transport of macromolecules across endothelium
M Ghim, Y Mohamied, PD Weinberg
Cardiovascular Engineering and Technology 12, 101-113, 2021
162021
Endothelial cells do not align with the mean wall shear stress vector
M Arshad, M Ghim, Y Mohamied, SJ Sherwin, PD Weinberg
Journal of the Royal Society Interface 18 (174), 20200772, 2021
142021
Computed tomography imaging of macrophage phagocytic activity in abdominal aortic aneurysm
J Toczek, P Boodagh, N Sanzida, M Ghim, M Salarian, K Gona, G Kukreja, ...
Theranostics 11 (12), 5876, 2021
132021
Disturbed flow increases endothelial inflammation and permeability via a Frizzled-4-β-catenin-dependent pathway
M Rickman, M Ghim, K Pang, AC von Huelsen Rocha, EM Drudi, ...
Journal of Cell Science 136 (6), jcs260449, 2023
92023
Positron emission tomography imaging of vessel wall matrix metalloproteinase activity in abdominal aortic aneurysm
J Toczek, K Gona, Y Liu, A Ahmad, M Ghim, D Ojha, G Kukreja, ...
Circulation: Cardiovascular Imaging 16 (1), e014615, 2023
92023
Differential BMP signaling mediates the interplay between genetics and leaflet numbers in aortic valve calcification
JJ Jung, AA Ahmad, S Rajendran, L Wei, J Zhang, J Toczek, L Nie, ...
Basic to Translational Science 7 (4), 333-345, 2022
72022
NO synthesis but not apoptosis, mitosis or inflammation can explain correlations between flow directionality and paracellular permeability of cultured endothelium
M Ghim, SW Yang, KRZ David, J Eustaquio, CM Warboys, PD Weinberg
International Journal of Molecular Sciences 23 (15), 8076, 2022
62022
Segmenting growth of endothelial cells in 6-well plates on an orbital shaker for mechanobiological studies
KT Pang, M Ghim, M Arshad, X Wang, PD Weinberg
Journal of Visualized Experiments (JoVE), 2021
62021
Investigation of Nanodroplet Adhesion to Endothelial Cells under Atheroprone Flow Conditions
G Zhang, KT Pang, M Ghim, PD Weinberg, MX Tang
2018 IEEE International Ultrasonics Symposium (IUS), 1-4, 2018
62018
Shear-mediated ALK5 expression regulates endothelial activation
KT Pang, M Ghim, P Sarathchandra, CM Warboys, MH Yacoub, ...
Biochemical and Biophysical Research Communications 642, 90-96, 2023
32023
Effects of multidirectional flow on cultured endothelium
MC Ghim
Imperial College London, 2016
22016
Multimodality Imaging of Aortic Valve Calcification and Function in a Murine Model of Calcific Aortic Valve Disease and Bicuspid Aortic Valve
AA Ahmad, M Ghim, J Toczek, A Neishabouri, D Ojha, Z Zhang, K Gona, ...
Journal of Nuclear Medicine 64 (9), 1487-1494, 2023
12023
Visualization of three pathways for macromolecule transport across cultured endothelium and their modification by flow (vol 313, pg H959, 2017)
M Ghim, P Alpresa, SW Yang, ST Braakman, SG Gray, SJ Sherwin, ...
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 319 (2 …, 2020
12020
LRG1 is a novel regulator of endothelial activation and is shear dependent: A Potential therapeutic target?
PDW KT Pang, CW Fhu, M Ghim, HM Tay, HW Hou, Q Lu, CM Warboys, X Wang
Atherosclerosis 275, 2018
12018
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