NKT Cells Coexpressing a GD2-Specific Chimeric Antigen Receptor and IL15 Show Enhanced In Vivo Persistence and Antitumor Activity against Neuroblastoma X Xu, W Huang, A Heczey, D Liu, L Guo, M Wood, J Jin, AN Courtney, ... Clinical Cancer Research 25 (23), 7126-7138, 2019 | 158 | 2019 |
Anti-GD2 CAR-NKT cells in relapsed or refractory neuroblastoma: updated phase 1 trial interim results A Heczey, X Xu, AN Courtney, G Tian, GA Barragan, L Guo, CM Amador, ... Nature Medicine, 1-10, 2023 | 90 | 2023 |
IL-12 reprograms CAR-expressing natural killer T cells to long-lived Th1-polarized cells with potent antitumor activity E Landoni, MG Woodcock, G Barragan, G Casirati, V Cinella, S Stucchi, ... Nature Communications 15 (1), 89, 2024 | 23 | 2024 |
LEF1 drives a central memory program and supports antitumor activity of natural killer T cells H Ngai, GA Barragán, G Tian, JC Balzeau, C Zhang, AN Courtney, L Guo, ... Cancer Immunology Research, 2022 | 14 | 2022 |
NKT Cells Coexpressing a GD2-Specific Chimeric Antigen Receptor and IL15 Show Enhanced X Xu, W Huang, A Heczey, D Liu, L Guo, M Wood, J Jin, AN Courtney, ... Vivo, 2019 | 13 | 2019 |
Interaction between tumor cell TNFR2 and monocyte membrane-bound TNF-α triggers tumorigenic inflammation in neuroblastoma JA Tomolonis, X Xu, KH Dholakia, C Zhang, L Guo, AN Courtney, S Wang, ... Journal for ImmunoTherapy of Cancer 11 (3), e005478, 2023 | 9 | 2023 |
Refining chimeric antigen receptors via barcoded protein domain combination pooled screening X Rios, O Pardias, MA Morales, P Bhattacharya, YX Chen, L Guo, ... Molecular Therapy, 2023 | 7 | 2023 |
Glypican-3-specific CAR-NKT cells overexpressing BATF3 mediate potent antitumor activity against hepatocellular carcinoma. RS Shaik, P Rathi, A Courtney, N Schneller, L Guo, G Barragan, C Zhang, ... Journal of Clinical Oncology 40 (16_suppl), e14521-e14521, 2022 | 3 | 2022 |
PRDM1 is a key regulator of the natural killer T–cell central memory program and effector function G Tian, GA Barragán, H Yu, C Martinez-Amador, A Adaikkalavan, X Rios, ... Cancer Immunology Research, 2025 | | 2025 |
Hyperleukocytosis in a neuroblastoma patient after treatment with natural killer T cells expressing a GD2-specific chimeric antigen receptor and IL-15 G Tian, AN Courtney, H Yu, S Bhar, X Xu, GA Barragán, CM Amador, ... Journal for ImmunoTherapy of Cancer 13 (1), e010156, 2025 | | 2025 |
GD2-CAR NKTS CAN INDUCE ANTITUMOR RESPONSES IN CHILDREN WITH NEUROBLASTOMA (NB) AND BTG1 REPRESSION CAN FURTHER BOOST THEIR THERAPEUTIC POTENTIAL IN NB MODELS AA Heczey, X Xu, AN Courtney, G Tian, GA Barragan, L Guo, CM Amador, ... PEDIATRIC BLOOD & CANCER 71, S8-S8, 2024 | | 2024 |